Publications

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2016
Faniran, A, Oluwagbenga OOI.  2016.  Creation and Environmental Care for Global Security and Peace: The Theocentric Option. American Journal Academic Research. 1(1):A12-A24. Abstractcreation-and-environmental-care-for-global-security-and-peace-the-theocentric-option.pdfWebsite

The main thrust of this paper is to assess the impacts of the human being on the environment as a result of their perception of the environment mainly as a resource that must be exploited. Particular attention was paid to different strategies adopted by scholars in terms of managing nature both in the past and present with a view to ascertaining the extent of degradation and the tendency of wanton anthropogenic modification of the environment. The study was based on archival research methods and expository review of relevant studies. Suggestions on how environmental sustainability could be attained in the near future were proposed. Finally, as an alternative to ecocentrism and anthropocentrism, a theocentric perspective was suggested since materialism was regarded as one of the most serious dysfunctional values for the ecosystem. Therefore Christians needed to re-orientate their relationship with the material properties.

Olorunfemi, E, Ojo J, Aboyeji OS, Akeju M, Okezie C.  2016.  DETERMINATION OF ELECTROMAGNETIC RADIATION LEVELS FROM CELL PHONES AND GSM MASTS IN ILE-IFE, SOUTHWEST NIGERIA. Ife Journal of Science. 18(4):1041-1051.olorunfemi_et_al_17.pdf
S, L, A I, Asani MA, Bolorunduro KA, Foghi PU, Oke IA.  2016.  EFFECT OF SELECTED FACTORS ON WATER SUPPLY AND ACCESS TO SAFE WATER IN NIGERIA. Ife Journal of Science. 18(3):623-639.lukman_et_al._5.pdf
Adegoke, OJ.  2016.  Effect of Valuation Variance and Inaccuracy on Nigerian Commercial Property Market: An Empirical Study. Journal of Property Investment and Finance,. 34(3)
Sola-Ojo, FE, A AA, F ayeye TR, A BAH, Ibiwoye DI, A FN.  2016.  EFFECTS OF FEEDING PROCESSED BAOBAB (Adansonia digitata) SEED ON THE HEAMATOLOGY AND SERUM BIOCHEMISTRY OF BROILER CHICKS. Ife Journal of Science. 18(4):895-903.sola-ojo_et_al_6.pdf
Ayoola, TJ, Oyerinde AA.  2016.  Efficiency and Financial Distress in the Nigerian Banking Industry. ICAN Journal of Accounting and Finance. 1(1):101-121.
Akinpelu, BA, Apata JT, Iwalewa EO, Oyedapo OO.  2016.  EVALU ATION OF ANTI-HYPERLIPIDEMIC POTENTIAL OF ETHANOLIC LEAF EXTRACT OF CLERODENDRUM VOLUBILE P . BEAUV .. Ife Journal of Science. 18(3):789-800.
L.A, J, E.T O, J.A A, A.A A.  2016.  EXPERIMENT AL INVESTIGATION OF FOULING CHARACTERISTICS OF DIESEL OIL. Ife Journal of Science. 18(3):721-728.jimoda_et_al_13.pdf
Adegoke, BF, Adegoke OJ, Oyedele, J.B.  2016.  Factors Influencing Women Participation in Homeownership in Nigeria. ournal of Property Management. 34(1):67-78.
Oluwagbenga, OOI, Fashae OA, Oke TO, Akinwumiju AS.  2016.  Flood Vulnerability in a Part of Southwestern Nigeria. Academic Journal of Environmental Science. 4(3):055-061.flood_vulnerability_in_a_part_of_southwestern_nigeria.pdf
Adeniyi, TA, Oyebanji OO, Adeonipekun PA.  2016.  FLORAL DIVERSITY IN THE WETLANDS OF IBEJU-LEKKI AREA, LAGOS, NIGERIA. Ife Journal of Science. 18(3):729-737.adeniyi_et_al_14.pdf
Fawole, OG, MacKenzie AR, Cai X.  2016.  Gas flaring and resultant air pollution: A review focusing on black carbon. Environmental Pollution. 216:182-197.
Bienczak, A, Cook A, Wiensner L, Olagunju A, Mulenga V, Kityo C, Kekitiinwa A, Owen A, Walker S, Gibb D, McIlleron H, Burger D, Denti P.  2016.  The impact of genetic polymorphisms on the pharmacokinetics of efavirenz in African children. British Journal of Clinical Pharmacology. doi: 10.1111/bcp.12934(Epub ahead of print) Abstract

AIM: To characterise the efavirenz steady-state pharmacokinetics in African children using model-based approach, quantifying demographic and genotypic effects on the drug's disposition, and conduct simulations allowing prediction of optimised doses of efavirenz in this population.

METHODS: We modelled the steady-state population pharmacokinetics of efavirenz in Ugandan and Zambian children using nonlinear mixed-effects modelling. Individual mid-dose efavirenz concentrations were derived and simulations explored genotype-based dose optimisation strategies.

RESULTS: A 2-compartment model with absorption through transit compartments well described 2086 concentration-time points in 169 children. The combined effect of SNPs 516GT and 983TC explained 44.5% and 14.7% of the variability in efavirenz clearance and bioavailability, respectively. The detected frequencies of composite CYP2B6 genotype were 0.33 for 516GG|983TT, 0.35 for 516GT|983TT, 0.06 for 516GG|983TC, 0.18 for 516TT|983TT, 0.07 516GT|983TC and 0.01 for 516GG|983CC. The corresponding estimated clearance rates were 6.94, 4.90, 3.93, 1.92, 1.36, and 0.74 L/h for a 15.4 kg child and median (95% CI) observed mid-dose concentrations 1.55 (0.51-2.94), 2.20 (0.97-4.40), 2.03 (1.19-4.53), 7.55 (2.40-14.74), 7.79 (3.66-24.59) and 18.22 (11.84-22.76) mg/L, respectively. Simulations showed that wild-type individuals had exposures at the bottom of therapeutic range, while slower metabolisers were over-exposed.

CONCLUSIONS: Dosage guidelines for African children should take into consideration the combined effect of SNPs CYP2B6 516G > T and 983 T > C.