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Conference Paper
Fadahunsi, JT, Sanyaolu ET.  2017.  Using GIS Technique for Assessing the Distribution of the Types of Bedrock in Osun State, Nigeria, 4-12 May. 52nd Annual General Meeting and Conference of the Nigeria Institution of Surveyors. , Yanagoa, Bayelsa State
Adewusi, AO, Oladokun TT.  2017.  Estimation of Longrun Relationship between Prices of Building Materials and Commercial Properties in Ibadan, Nigeria., 22nd to 24th May. Proceedings of Environmental Design and Management International Conference,. , Ile Ife, Nigeria
T. O. Ayodele, Oladokun TT.  2017.  Factors Influencing Academic Students Satisfaction in Obafemi Awolowo University, Ile Ife: A case Study of Estate Management Students., 22nd to 24th May. Environmental Design and Management International Conference. , Ile Ife, Nigeria
Idowu, PA, OB A, OL US, KA G.  2016.  Beyond Crude: Implementation Of Neuro-Fuzzy Model For Efficient Weather Prediction In Agro-Based Economy (Nigeria)., October 5. the 10th International Conference on ICT Applications. , OAU Ile-Ife
Idowu, PA, OB A, OL US, I R.  2016.  Empirical Study on Information and Communication Technology Infusion among Medical Students in Nigeria, October 5. Proceedings of the 10th International Conference on ICT Applications. , OAU Ile-Ife
Olaofe, O, Onwubuya M, Owoyele M, Ezike K.  2016.  Morphological spectrum of orbitoocular diseases in a tertiary health centre in Keffi, North Central Nigeria, 2016. 469(SUPPL 1):S206-S206.: SPRINGER ONE NEW YORK PLAZA, SUITE 4600, NEW YORK, NY, UNITED STATES Abstract
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OlutolaAgbelusi, Aladekomo TA, Idowu PA.  2015.  Prediction of Pediatric HIV/AIDS Survival in Nigeria Using Naïve Baye’s Approach, July 22-24. Information Technology for Inclusive Development. , Akure Nigeria
Aderibigbe, A, Ekemode BG, Adegoke OJ.  2015.  An Assessment of Land Title Registration in Osun Nigeria, 3 September. the 15th African Real Estate Society International Conference on Real Estate Markets Development: Meeting the Challenge, Making the Difference. , Golden Tulip Kumasi City Hotel, Kumasi, Ghana,
Adegoke, BF, Adegoke OJ.  2015.  Evaluation of Benefits of Women Participation in Homeownership in Nigeria, 3 September. 15th African Real Estate Society International Conference on Real Estate Markets Development: Meeting the Challenge, Making the Difference. , Golden Tulip Kumasi City Hotel, Kumasi, Ghana,
Odeyemi, TI, Mosunmola OO.  2015.  Stakeholders, Information and Communication Technologies platforms and the 2015 General Elections in Nigeria, 28th July. National Conference on the 2015 General Elections in Nigeria: The Real Issues. , The Electoral Institute, Independent National Electoral Commission, Abuja, Nigeriastakeholders_icts_platforms_and_the_electoral_process_odeyemi_mosunmola_ed.pdf
Odediran, S, Windapo A, Ojo G, A. M.  2015.  ICT Knowledge Diffusion in the Nigerian Quantity Surveying Education, 07. Abstract
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Folárànmí, S, Oyèníyì Oyèwolé.  2015.  {Changing the face of the built environment through murals: The Ile-Ife example}. Responsive Built Environment, Issues, Strategies and Policies in the Developing World.. (Odeyinka, Henry, Aluko, Bioye, Amole, Oludolapo, Ademuleya, Babasehinde, {Daramola, Oluwole (Ọbáfémi Awólọ́wọ̀ University, Ile-Ife}, Nigeria.), Eds.).:47–56., Ile-Ife: Faculty of Environmental Designs and management Obafemi Awolowo University, Abstract

Art is known to be an agent of value and aesthetic in the built environment wherever such forms of art are employed, especially in societies where they are appreciated and enjoyed. Murals as a form of public art particularly have taken up a form by creating a symbiotic relationship with the spaces and walls within cities, towns and private homes. The lack of appreciation of this art form in the Nigerian environment and its non-inclusiveness in the past has devoid this art of its value. The paper discusses the recent murals in Ile-Ife especially on the walls of Obáfémi Awólówò University campus with a view to determining their social and environmental relevance in the built up spaces. It adopts structured interview to collect data from users of public spaces. The study population comprised of students, staff and other public space users in the study area. A descriptive approach was used in analyzing the murals based on form and subject matter as it relates to the public space. Findings revealed that public space users are receptive to the new murals and view them as a positive development. Results also showed that more spaces should be made available for use of posters as well as for art. The study concluded that the recent murals have added more value and aesthetic appeal to the spaces in which they are painted, thereby receiving positive responses from users of public spaces. It suggested that a policy should be enacted to incorporate creation of art as part of the budget in the design and construction of public spaces.

Folárànmí, S, Imafidor J.  2015.  {The Stained-Glass of Selected Churches in Ibadan}. Responsive Built Environment, Issues, Strategies and Policies in the Developing World.. (Odeyinka, Henry, Aluko, Bioye, Amole, Oludolapo, Ademuleya, Babasehinde, {Daramola, Oluwole (Ọbáfémi Awólọ́wọ̀ University, Ile-Ife}, Nigeria.), Eds.).:97–107., Ile-Ife: Faculty of Environmental Designs and management Obafemi Awolowo University, Abstract

Art has always been and is still being used as a veritable tool in the hands of artists in promoting the Christian religion. Sculptures, mosaics, murals and stained-glass are some of the artistic media used to augment the aesthetic appeal of church architecture and most importantly earn the Christian faithful better concentration. However, the quest for larger spaces to accommodate the growing population of Christian converts and recent development in the built environment led to the demolition/renovation of existing structures and as a result churches give little or no room for the survival of some artworks. Artworks such as murals and stained-glass which are directly executed or fitted permanently on walls are usually affected as a result of these developments. This paper identified and analyzed the existing stained-glass in selected churches in Ibadan with a view to establishing their functions and relevance in the public spaces. The study adopted art historical methodology by using direct observatory and descriptive analysis. Interviews were conducted with key informants in the study area. Findings revealed that most churches with stained-glasses in the study area are old churches belonging to the Catholic, Methodist and Anglican denominations, and that many new churches no longer incorporate stained-glass in their churches, thereby depriving the built environment of this artistic form. It recommends that some of these churches be designated as tourist sites and be preserved for the good of the built environment as it is practiced in developed nations of the world.

Lal, C, DiSanto G, Caputo M, Panighel M, Taleatu BA, Goldoni A, Jain IP.  2014.  Electronic Structure of Fe3Si on Si(100) Substrates, Dec.. AIP Proceedings. , India
Olagunju, A, Siccardi M, Okafor O, Bolaji O, Khoo S, Owen A.  2014.  Pharmacogenetics of efavirenz excretion into human breast milk and transfer to breastfed infants [Abstract #888], 3-6 March. 21st Conference on Retroviruses and Opportunistic Infections (CROI). , Boston, MA, USA Abstract

Background: The influence of drug metabolizing enzyme, transporter and nuclear receptor single nucleotide polymorphisms (SNPs) on efavirenz (EFV) concentrations in human breast milk and infants exposed through breast milk is understudied. SNPs in maternal CYP2B6, NR1I3, ABCG2 and ABCB5 were investigated here.

Methods: HIV positive nursing mothers (n = 51) receiving once daily regimens containing 600 mg EFV and their exclusively breastfed infants were recruited from 3 Nigerian hospitals. Paired dried blood spots (DBS; maternal and infant) and dried breast milk spots (DMS) were collected 12 - 14 hours post maternal dose. EFV was quantified by validated LC-MS/MS. Plasma EFV concentration was estimated using [DBS[EFV]/(1-HCT)]*fbpp, where HCT is average haematocrit and fbpp is fraction bound to plasma protein. Genotyping for CYP2B6 rs3745274, NR1I3 rs2307424, NR1I3 rs3003596, ABCB5 rs6461515, ABCB5 rs2301641, ABCG2 rs2231164 and ABCG2 rs2622604 was conducted. Associations of EFV concentrations with SNPs and demographic factors were investigated by univariate (Mann-Whitney U test) and multivariate analyses (multiple linear regression). P < 0.05 was considered statistically significant.

Results: Median (IQR) EFV breast milk concentration was 2280 (1180, 3270) ng/ml. Using 150ml/kg/day as average milk intake, this equates to ~340 (177, 491) ug/kg/day infant dose and resulted in 178 (87.7, 340) ng/ml in infant plasma. Maternal plasma EFV was 2310 (1580, 4460) ng/ml and median (IQR) milk-to-maternal plasma ratio was 0.82 (0.51, 1.1). There were significant correlations between maternal plasma and breast milk EFV concentrations (p = 1.3 x 10-12; rho = 0.80) and between breast milk and infant plasma (p = 7.9 x 10-5; rho = 0.52). Significant differences in maternal, infant and breast milk EFV concentrations were observed based on CYP2B6 rs3745274 genotypes (Figure 1). Only CYP2B6 rs3745274 was independently associated with breast milk [B = 0.22 (0.10, 0.35), p = 0.001], maternal [B = 0.23 (95% CI: 0.13, 0.32), p=1.5 x 10-5] and infant [B = 0.23 (0.09, 0.37), p = 0.002] EFV concentrations in multivariate analyses. Other statistically significant SNP associations were observed in univariate but not multivariate analysis.

Conclusion: CYP2B6 rs3745274 was independently associated with EFV concentrations in human breast milk and infants exposed through breast milk. Further study is warranted to define clinical significance and implications for stratified medicine in these patients.

Siccardi, M, Olagunju A, Simiele M, D’Avolio A, Calcagno A, Perri GD, Bonora S, Owen A.  2014.  Relative genetic contribution to the pharmacokinetics of commonly prescribed antiretrovirals (Abstract #504), 3-6 March. 21st Conference on Retroviruses and Opportunistic Infections (CROI). , Boston, MA, USA Abstract

Background: Antiretroviral pharmacokinetics is characterised by broad variability influenced by numerous factors affecting absorption, distribution, metabolism and elimination. Recently, a relative genetic contribution (rGC) of 0.904 (0.64 – 0.97) was reported for nevirapine (NVP) AUC0-6h (Micheli et al, Pharmacogenet Genomics, 2013). The aim of this study was to assess the Cmin rGC for a panel of antiretroviral drugs to rank agents according to the degree to which heritability influences their pharmacokinetics.

Methods: Patients from the Therapeutic Drug Monitoring Registries of the University of Turin and the University of Liverpool were included in the study. Inclusion criteria for both cohorts were as follows: receiving boosted lopinavir (LPV/r, 300/100 mg twice daily), boosted atazanavir (ATV/r 300/100 mg once daily), unboosted ATV (ATV, 400mg once daily), efavirenz (EFV, 600 mg once daily), NVP (400 mg once daily) or raltegravir (RAL, 400 mg twice daily), age>18 years, not receiving drugs known to contribute to drug-drug interactions. Plasma drug concentrations were determined using validated HPLC or LC-MS/MS methods. Intrapatient (SDw) and interpatient (SDb) variability were measured in patients with plasma concentrations available from more than one occasion. The rGC was calculated using the following equation: 1-(1/F) where F= SDb2/SDw. Statistical significance for genetic contribution was calculated using F-test, α = 0.05.

Results: A total of 211 patients were included in the study, 37 receiving LPV/r, 24 receiving ATV/r, 24 receiving ATV, 82 receiving EFV, 20 receiving NVP and 24 receiving RAL. SDw and SDb were 38% and 43% for LPV/r (n = 37), 49% and 50% for ATV/r (n = 24), 54% and 104% for ATV (n = 24), 33% and 60% for EFV (n = 82), 19% and 44% for NVP (n = 20), and 81% and 95% for RAL (n = 24), respectively. Mean with 95% CI rGC was calculated to be 0.35 (0.06-0.55) for LPV/r, 0.15 (0-0.6) for ATV/r, 0.55 (0.35 – 0.7) for ATV, 0.78 (0.68 – 0.85) for EFV, 0.82 (0.62-0.91) for NVP and 0.08 (0-0.56) for RAL (Figure). Genetic contribution was statistically significant (p<0.05) for ATV, EFV and NVP.

Discussion: The rank order for genetic contribution to variability in Cmin for the study drugs was NVP > EFV > ATV > LPV/r > ATV/r > RAL indicating class specific differences exist. Interestingly, these data indicate that ritonavir reduces the genetic contribution to variability in ATV Cmin presumably through inhibition of gene products such as CYP3A4 and ABCB1. Drugs with higher rGC scores may represent better candidates for pharmacogenetic studies.

Awoleye, OM, Ilori MO, Oluwale BA, Olaposi TO.  2014.  Assessment of Indigenous Family Business Promotion., 13 July. Joint World Conference on Social Work, Education and Social Development. , Melbourne, Australia
Opawole, A, Onajite J, J.K. O, S.G. A.  2014.  Risks Associated with Concession-Based Contracts in Lagos State, Nigeria, 01. Abstract
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  2014.  Development of a Multimedia Mobile Dictionary of Greeting Terms for Nigerian Indigenous Languages. Proceedings of 5th International Conference on Mobile e-Services. , Nigeriapapere5xvi.pdf
Lal, C, Jain IP, DiSanto G, Caputo M, Panighel M, Taleatu BA, Goldoni A.  2013.  XPS study of 2H-TPP at Fe/Si(111) system, Dec. 2012. AIP Proceedings. , India