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2011
Fisusi, AA, Adeniran SA, Awe OP.  2011.  Direct Sequence CDMA System using Finite-Time Altered Sinusoidal Signals as Orthogonal Signatures, 24-26 November . 3rd IEEE International Conference on Adaptive Science and Technology (ICAST 2011). , Abuja, Nigeria
Alatise, O, Lawal O, Adisa A, Arowolo O, Ayoola O, Agbakwuru A, Adesunkanmi A, Omoniyi-Esan G, Olaofe O.  2011.  Audit of Management of Gallbladder Cancer in a Nigerian Tertiary Health Facility, 2011/10/26. 43:472-80. Abstract

Gallbladder cancer is a rare malignancy with a variable incidence worldwide. It ranks number eight among all gastrointestinal cancer seen in Nigeria. It is associated with high mortality and morbidity because it is usually diagnosed very late. Adequate surgical resection is the only modality with hope of cure. This requires advanced surgical skills which is quite rare in most developing countries like Nigeria. In this current work, we audit the management and outcome of gallbladder cancer in our hospital, highlighting peculiarity associated with our setting.Consecutive patients managed as cases of gallbladder cancer at Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria between January 1990 and December 2010 were studied retrospectively. Patient demographics, disease and treatment-related variables, and outcomes were analyzed by SPSS version 16.0.
Thirty-one cases of gallbladder cancer were diagnosed over the 21-year period, and this accounts for about 0.3% of all cancer cases seen in our hospital. The median age of this patient cohort was 58 years (range 28 to 79 years). Seventeen (54.8%) patients were age below 60 while 14 (45.2%) were age 60 and above. Twenty-seven patients (87.1%) were female and four (12.9%) were male, with a male to female ratio approximately 1:7. Over 80% of the patients presented with a triad of upper abdominal pain, weight loss, and jaundice. Majority (67.7%) of the patients were diagnosed intraoperatively. Only four patients underwent complete resection as they had radical cholecystectomy including regional lymph node dissection and wedge resection of the gallbladder fossa of the liver. The stages of the resected patients were T3 in three patients and T2 in one. Overall 1- and 5-year survival rates for our entire patient cohort were 32% and 10%, respectively.
In conclusion, this study showed that preoperative diagnosis of gallbladder cancer could be challenging in our environment. A triad of upper abdominal pain, jaundice, and weight loss with judicious use of available radiological modality will increase the chances of making the preoperative diagnosis of the cancer. It also showed that good outcome can be obtained when radical surgery is offered to these few patients within the limitation of resources in few patients with resectable tumor.

Adesina, O, Kolawole B, Ikem R, Adebayo O, Soyoye D.  2011.  Comparison of lispro insulin and regular insulin in the management of hyperglycaemic emergencies, 2011/03/01. 40:59-66. Abstract

This study compared the efficacy and safety of Lispro insulin and regular insulin in the management of hyperglycemic emergencies (HE). Fifty patients who presented in HE to the Emergency unit of Obafemi Awolowo University Teaching Hospitals Complex, Ile Ife participated in the study. Hyperglycaemic emergency was diagnosed when plasma glucose level was >17 mmol/L (300 mg/dl) in the presence of polyuria and polydipsia that warrants emergency hospital admission. Subjects in the Lispro insulin group had a statum dose of 0.3 IU/kg, while those in the regular insulin group had a statum dose of 20 IU equally split between the intravenous and intramuscular routes. Further insulin therapy was by the intramuscular route. Data was analysed using the Statistical package for social sciences (SPSS) version 11. Hyperglycaemia resolved within the first 8 hours in 60 and 40% percent of subjects in the lispro and regular insulin treated groups respectively. The time taken for resolution of hyperglycaemia was similar in both treatment groups, 6.6 +/- 0.8 hours for the lispro insulin group and 7.4 +/- 0.8 hours for the regular insulin group p = 0.51. The number of episodes of hypoglycaemia and hypokalemia in the two treatment groups did not differ statistically (p = 1.0 and 0.38 respectively). Eight (16%) subjects died. Lispro insulin is a safe and efficacious alternative to regular insulin in the treatment of HE.

A, O, Folayan M, T O, Harris G, Ogunbodede E.  2011.  Health workers perception of hospital’s institutional structure, 2011/01/01. American Journal of Tropical Medicine and Public Health. 1:79-88. Abstract
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A, O, Folayan M, T O, Harris G, Ogunbodede E.  2011.  Health workers perception of hospital’s institutional structure, 2011/01/01. American Journal of Tropical Medicine and Public Health. 1:79-88. Abstract
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Amusa, Y, Eziyi J, Akinlade O, Famurewa OC, Adewole SA, Nwoha PU, Ameye S.  2011.  Volumetric measurements and anatomical variants of paranasal sinuses of Africans (Nigerians) using dry crania, 2011/01/01. 3:399-303. Abstract
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Eziyi, J, Amusa YB, Nwawolo C, Ezeanolue B.  2011.  Wax Impaction in Nigerian School Children., 2011/01/01. 16 Abstract
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Sunmonu, TA, Afolabi OT, Komolafe MA, Ogunrin AO.  2011.  Patients' knowledge about their disorder: Perspective of patients with epilepsy in a tertiary health facility in southwestern Nigeria, 2011. Epilepsy and Behavior. 20(3) Abstract

Objective: Previous studies have shown that patients with epilepsy do not have adequate knowledge about their disorder, suggesting that patient education is a vital part of comprehensive care for epilepsy. The goal of this study was to evaluate what Nigerian patients with epilepsy know about their disorder. Methods: Forty-six patients with EEG- and clinically confirmed epilepsy participated in the study. The patients completed the Epilepsy Patients Knowledge Questionnaire. The questionnaire includes topics related to etiology of epilepsy, safety, compliance, legal issues of driving, and employment. The questionnaire scores were correlated with demographic variables, duration of epilepsy, and level of education of the patients. Results: The mean age of the respondents was 26.78 ± 9.27. years; there were 27 males and 19 females. The mean duration of epilepsy in the group was 7.6 ± 7.5. years. The mean rates of correct responses to the issues of safety and compliance were 31.6 and 76.8%, respectively. The mean scores on legal issues of driving and employment were 45.7 and 42.4%, respectively. The lowest score (10.9%) was on the etiology of epilepsy. Conclusion: Nigerian patients with epilepsy lack adequate knowledge about their disorder, and there is a need for improved educational intervention in these patients. © 2010.

Omoniyi-Esan, O, Olaofe O, Onwubuya M, Fadahunsi O, Komolafe A.  2011.  Pattern of deaths in females in a tertiary health center, south-west Nigeria, 2011. 3:307.: Dove Press Abstract
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Komolafe, MA, Sunmonu TA, Fabusiwa F, Komolafe EO, Afolabi O, Kett M, Groce N.  2011.  Women's perspectives on epilepsy and its sociocultural impact in South Western Nigeria, 2011. African Journal of Neurological Sciences. 30(2) Abstract

Background There has been little study of the specific implications of living with epilepsy for women in societies where they already face gender based marginalization. Purpose Understanding the sociocultural aspects of epilepsy in women will help to improve the management of epilepsy in the community. Methods A series of six focus groups were held in urban and rural Southwest Nigeria. Results Epilepsy was commonly attributed to a spiritual attack, witchcraft and other supernatural causes. Denial of the diagnosis of epilepsy was common among women with nocturnal or focal seizures. Majority of women with epilepsy preferred multiple modalities of care in the following order: traditional, spiritual and western. The cost of traditional care was astronomical and most were already impoverished by the time they sought western care. WWE experienced stigma, social exclusion, isolation particularly from paternal relations, in -laws, and community members. Epilepsy related stigma contributed to schooling problems, difficulty in getting married, separation, divorce and problems with childcare and role fulfilment. One unanticipated result of this study was that public announcements made to identify rural study participants created a demand for western health services in rural populations previously unaware that epilepsy could be controlled through western medication. Conclusion Women with epilepsy face significant and persistent social, economic and cultural barriers. There is the need to educate women, their family and community members to reduce misconceptions and stigma. Community based medical treatment can be improved by taking into consideration the surrounding social, economic and cultural challenges faced by women with epilepsy. The care of epilepsy need to be incorporated into the primary health care system; regular awareness campaigns to be carried out in order to improve knowledge and attitudes and reduce stigma and social exclusion of women with epilepsy. Specific social welfare programmes and educational programme should be established to encourage the full integration of women with epilepsy in the society. © 2002-2012 African Journal of Neurological Sciences. All rights reserved.

Stephen, A, Raji Y.  2011.  Long-Term Administration of Artesunate Induces Reproductive Toxicity in Male Rats, 10. Journal of reproduction & infertility. 12:249-60. Abstract
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Stephen, A, Raji Y.  2011.  Prolonged administration of proguanil induces reproductive toxicity in male rats, 10. The Journal of toxicological sciences. 36:587-99. Abstract
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Omideyi, A, Akinyemi A, Aina O, Adeyemi A, Fadeyibi O, Bamiwuye O, Akinbami C, Anazodo A.  2011.  Contraceptive Practice, Unwanted Pregnancies and Induced Abortion in Southwest Nigeria, 07. Global public health. 6 Suppl 1:S52-72. Abstract
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Ojo, G, Odediran S, Adeyinka BF, Oparinde D.  2011.  APPRAISAL OF MAINTENANCE COST OF TOURISM CENTERS IN OSUN STATE, 01. :152-169. Abstract
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Ojo, G, Odediran S, Adeyinka B, Oparinde D.  2011.  APPRAISAL OF MAINTENANCE COST OF TOURISM CENTERS IN OSUN STATE, 01. :152-169. Abstract
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Ojo, G, Odediran S, Adeyinka BF, Oparinde D.  2011.  APPRAISAL OF MAINTENANCE COST OF TOURISM CENTERS IN OSUN STATE, 01. :152-169. Abstract
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Akinsiku, O, Babatunde S, Opawole A.  2011.  Comparative accuracy of floor area, storey enclosure and cubic methods in preparing preliminary estimate in Nigeria, 01. Journal of Building Appraisal. 6 Abstract
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Opawole, A, Jagboro G, Babatunde S.  2011.  Factors Influencing the Implementation of Public Infrastructure in Nigeria., 01. 11:28-38. Abstract
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Amusa, Y, Badmus A, Olabanji J, Oyebamiji E.  2011.  Laryngeal carcinoma: Experience in Ile-Ife, Nigeria, 01. Nigerian journal of clinical practice. 14:74-8. Abstract
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Osunbitan, JA, Adekalu KO, Aina PO.  2011.   Adsorption Behavior of Manganese from Dithane M – 45 to Two Soil types in Southwestern Nigeria. Canadian Journal on Environmental, Construction and Civil Engineering. 2(5):43-49.
Ogundipe OK, Ugboko VI, FJ O.  2011.   Can Autologous Platelet-Rich Plasma Gel Enhance Healing After Surgical Extraction of Mandibular Third Molars? J Oral Maxillofac Surg.. 69:2305-2310,.
Alao, K, Adebowale OF, Akintomide AG.  2011.   Cultural barriers to initiating counselling relationships in Nigerian secondary schools: the Ile-Ife experience.. The counsellor, 30. 30(2):46–61..
Oladokun, T.T., Gbadegesin JT, Odunfa VO.  2011.   Factors influencing Effective Property Rights Governance In Lagos State. Urban Governance and Environmental Challenges in a West African Sub Region. , Ile Ife, Nigeria: Faculty of Environmrntal Design and management, OAU