Publications

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Ayanwale, A, Alao O, Ayinde J, Olugbade Y, Oyedele D, Adebooye O.  2018.  Branded Radio Program and Awareness of Under-utilized Indigenous Vegetable Innovations in Southwestern Nigeria (Innovation Dissemination through Branded Radio Program), 2018/04/18. Journal of Agricultural & Food Information. Abstract
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Adisa, AO, Gukas ID, Lawal OO, Adesunkanmi ARK.  2010.  Breast cancer in Nigeria: Is non-adherence to chemotherapy schedules a major factor in the reported poor treatment outcome? The breast journal. 16:206–207., Number 2: Wiley Online Library Abstract
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Adisa, AO, Gukas ID, Lawal OO, Adesunkanmi ARK.  2010.  Breast cancer in Nigeria: Is non-adherence to chemotherapy schedules a major factor in the reported poor treatment outcome? The breast journal. 16:206–207., Number 2: Wiley Online Library Abstract
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Idowu, PA, Williams KO, Balogun JA, Oluwaranti AI.  2015.  Breast Cancer Risk Prediction Using Data Mining Classification Techniques. Transactions on Networks and Communications. 3(2):1-11.
Olagunju, A, Bolaji O, Amara A, Waitt C, Else L, Adejuyigbe E, Siccardi M, Back D, Khoo S, Owen A.  2015.  Breast milk pharmacokinetics of efavirenz and breastfed infants' exposure in genetically-defined subgroups of mother-infant pairs: an observational study. Clinical Infectious Diseases. AbstractWebsite

Background. The antiretroviral drug efavirenz is widely used during breastfeeding. Evaluating its safety requires an understanding of its breast milk pharmacokinetics, level of breastfed infants' exposure and potential influence of polymorphisms in drug disposition genes.

Methods. For this observational study, we investigated plasma and breast milk pharmacokinetics of efavirenz and breastfed infants' exposure in HIV positive nursing mothers and their breastfed infants. We also evaluated potential variability due to genetic polymorphisms in CYP2B6, NR1I3, CYP2A6, ABCB1, ABCB5 and ABCG2.

Results. CYP2B6 516G>T was independently associated with efavirenz concentrations in maternal plasma, breast milk and infant plasma (n=134). When stratified based on CYP2B6 516G>T (n=29 ; 11 GG, 10 GT and 8 TT), EFV pharmacokinetic parameters in plasma and breast milk differed significantly between patient groups. The median time averaged milk-to-plasma concentration ratio was 1.10 (range: 0.57-1.71). The estimated maximum infant efavirenz dose from breast milk was 809 µg/kg/day (215-2760) and paediatric dose weight-adjusted exposure index was 4.05% (1.08-13.8). Infant plasma concentrations did not change significantly during the dosing interval, 157 ng/mL (28.6-1360) in pooled analysis and 315 ng/mL (108-1360) in CYP2B6 516TT group. Infant plasma concentrations were highest up to 8 days of age at 1590 ng/mL (190-4631) and decreased by about 90% in the age stratum day 9 to 3 months. No efavirenz related toxicity was reported.

Conclusions. Most breastfed infants are exposed to less than 10% of the weight-adjusted therapeutic paediatric dose, the safety threshold for exposure to maternal drugs from breast milk.

Olagunju, A, Bolaji O, Amara A, Waitt C, Else L, Adejuyigbe E, Siccardi M, Back D, Khoo S, Owen A.  2015.  Breast milk pharmacokinetics of efavirenz and breastfed infants’ exposure in genetically-defined subgroups of mother-infant pairs: an observational study. Clinical Infectious Diseases. 61(3):453-63. Abstract

BACKGROUND: The antiretroviral drug efavirenz is widely used during breastfeeding. Evaluating its safety requires an understanding of its breast milk pharmacokinetics, level of breastfed infants' exposure, and potential influence of polymorphisms in drug disposition genes.

METHODS: For this observational study, we investigated plasma and breast milk pharmacokinetics of efavirenz and breastfed infants' exposure in human immunodeficiency virus positive nursing mothers and their breastfed infants. We also evaluated potential variability due to genetic polymorphisms in CYP2B6, NR1I3, CYP2A6, ABCB1, ABCB5, and ABCG2.

RESULTS: CYP2B6 516G>T was independently associated with efavirenz concentrations in maternal plasma, breast milk, and infant plasma (n = 134). When stratified based on CYP2B6 516G>T (n = 29 ; 11 GG, 10 GT and 8 TT), efavirenz pharmacokinetic parameters in plasma and breast milk differed significantly between patient groups. The median time-averaged milk-to-plasma concentration ratio was 1.10 (range: 0.57-1.71). The estimated maximum infant efavirenz dose from breast milk was 809 µg/kg/day (215-2760) and pediatric dose weight-adjusted exposure index was 4.05% (1.08-13.8). Infant plasma concentrations did not change significantly during the dosing interval, 157 ng/mL (28.6-1360) in pooled analysis and 315 ng/mL (108-1360) in CYP2B6 516TT group. Infant plasma concentrations were highest up to 8 days of age at 1590 ng/mL (190-4631) and decreased by about 90% in the age stratum day 9 to 3 months. No efavirenz related toxicity was reported.

CONCLUSIONS: Most breastfed infants are exposed to <10% of the weight-adjusted therapeutic pediatric dose, the safety threshold for exposure to maternal drugs from breast milk.

Oziegbe, EO, Adekoya-Sofowora CA, Esan TA, Owotade FJ, Folayan MO.  2010.  Breastfeeding pattern and eruption of primary teeth in Nigerian children. Pediatric Dental Journal . 20(1):1-6.
Folayan, MO, Oziegbe EO, Esan AO.  2010.  Breastfeeding, timing and number of erupted teeth in first twelve months of life in Nigerian children. European Archives of Peadiatric Dentistry . 11(6):279-282.
ADESOLA, F.  1998.  The Bretton Woods Institutions and Democratization in Nigeria. Ife Social Sciences Review. (July Edition):106–113..
Oladokun, TT, Olaleye A.  2018.  Bridging Skill gaps in Real Estate Education in Nigeria.. Pacific Rim Property Research Journal. . 24 (1 ):17-34.bridging_skill_gap_in_real_estate_education_in_nigeria.pdf
Omolaye, BV, Adekogbe OS.  2018.  Bridging the gap between gown and town among gospel musicians in Ile-Ife. : Association of Nigerian Musicologists (JANIM) Abstract
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Akinbobola, TO.  2011.  Budget Deficit and inflation in Nigeria: A Causal Relationship. Journal of Emerging Trends in Economics and Mangement Sciences. Vol. 2(1):1-8.
Oluwatope, AO, Oyewo DT, Olayiwola FE, Aderounmu GA, Adagunodo EA.  2012.  Buffer Ocupancy of Double-Buffer Traffic Shaper in Real-Time Multimedia Applications across Slow-Speed Links. Communications and Network. abstract17.docx
Osasona, CO.  2021.  Building Renewal: The Centrality of Eventual Occupancy in Design Decisions. STREMAH XVII. :15-28., Southampton, UK: Wessex Institute of Technology, WIT
Okewole, IA, Daramola SA, Ajayi CA, Ogunba OA,(ed.) OKT.  2006.  The Built Environment : Innovation Policy and Sustainable Development. Proceedings of an International Conference by Covenant University, Ota.. , Ota, Ogun State
Okewole, IA, Daramola SA, Ajayi CA, Ogunba OA, K.T. Odusami(eds.).  2006.  The Built Environment: Innovation, Policy & Sustainable Development. , Sango Ota: Covenant University Press,
Mahmoud, B, Mirghni AA, Fasakin O, Oyedotun K, Manyala N.  2020.  Bullet-like microstructured nickel ammonium phosphate/graphene foam composite as positive electrode for asymmetric supercapacitors, 2020/04/23. 10:16349-16360. Abstract

Unique microstructured nickel ammonium phosphate Ni(NH4)2(PO3)4·4H2O and Ni(NH4)2(PO3)4·4H2O/GF composite were successfully synthesized through the hydrothermal method with different graphene foam (GF) mass loading of 30, 60 and 90 mg as a positive electrode for asymmetric supercapacitors. The crystal structure, vibrational mode, texture and morphology of the samples were studied with X-ray diffraction (XRD), Raman spectroscopy, Brunauer–Emmett–Teller (BET) surface area analysis and scanning electron microscopy (SEM). The prepared materials were tested in both 3-and 2-electrode measurements using 6 M KOH electrolyte. The composite material Ni(NH4)2(PO3)4·4H2O/60 mg exhibited a remarkable gravimetric capacity of 52 mA h g⁻¹, higher than the 34 mA h g⁻¹ obtained for the Ni(NH4)2(PO3)4·4H2O pristine sample, both at 0.5 A g⁻¹. For the fabrication of the asymmetric device, activated carbon from pepper seed (ppAC) was used as a negative electrode while Ni(NH4)2(PO3)4·4H2O/60 mg GF was adopted as the positive electrode. The Ni(NH4)2(PO3)4·4H2O/60 mg GF//ppAC asymmetric device delivered a specific energy of 52 Wh kg⁻¹ with an equivalent specific power of 861 W kg⁻¹ at 1.0 A g⁻¹ within a potential range of 0.0–1.5 V. Moreover, the asymmetric device displayed a capacity retention of about 76% for over 10 000 cycles at a high specific current of 10.0 A g⁻¹.

Jegede, T, Tunde-Ayinmode M, Jegede T, Akinsulore A, Ibigbami O.  2021.  Bullying Behavior Roles and Mental Health Correlates Among Secondary School Students in Ilesa, Nigeria, 2021/07/01. Abstract

Objective: Bullying behaviour is pervasive, cuts across age group, transcends geographical location and its impacts include but not limited to physical or academic snags. The objective of the study is to determine bullying roles and their association with emotional or behavioural problems among adolescents in Ilesa, Nigeria. Methods: A cross-sectional study was performed on 432 senior secondary school students (12-18 years old) in Ilesa (Nigeria). Peer Relationship Questionnaire was used to determine bullying roles and the Strength and Difficulty Questionnaire to measure behavioural problems. Results: Prevalence of bullying behaviour is high. The bully-victims had the highest means score on all subscales except pro-social. Similarly, the bully-victims was significantly associated with all subscales of the SDQ except the pro-social problems at (P< .001), (P=.024), (P= .004), (P= .004), and (P< .001) for conduct, emotional problem, hyperactivity problem, peer relationship problem and the total difficulty score respectively. Conclusion: This shows that participating in bullying behaviour irrespective of the role played increases the likelihood of psychological consequences, especially the bully-victim. There is a need to establish anti-bullying programs in schools to curb this menace and its mental health consequence.

Osundina, AF, Fatoye FO, Akanni OO, Omoreagba JO, Akinsulore A, Oloniniyi IO.  2017.  Burden and coping styles among caregivers of patients with major mental disorders and hypertension attending a Nigerian tertiary hospital. Indian Journal of Social Psychiatry. 33(3):189.: Medknow Publications Abstract
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Olowookere, S, Badmus S, Laoye O, Ijadunola M, Hassan M.  2019.  Burden of family caregivers of ophthalmic patients in a university teaching hospital in south-west Nigeria, 03. Malawi Medical Journal. 31:39-44. Abstract
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Olowookere, S.  2019.  Burden of family caregivers of ophthalmic patients in a university teaching hospital in south-west Nigeria. Malawi Medical Journal. 31:39–44., Number 1 Abstract
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Esan, O, Akinwande IO, Esan OT, Soyoye D.  2021.  Burden of musculoskeletal disorders among diabetics and their functional capacity in Southwest, Nigeria, 2021/01/01. 20:15. Abstract
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