Background: An increase in resistance against many different drugs among urinary tract infection (UTI) E coli isolates has been observed in the last 2 decades. This study determined the trends of antimicrobial resistance in E coli to commonly used antibiotics. Methods: The study was conducted in Ile-Ife, southwest Nigeria. Patients with features suggestive of UTI were investigated for presence of significant bacteriuria. Urine isolates were identified. Antimicrobial susceptibility was evaluated in accordance with standard bacteriological methods. Results: Of 442 urine specimens, 158 (35.8%) yielded significant growth, including 41 (25.6%) with E coli. Among the E coli isolates, antimicrobial susceptibility varied in prevalence by agent in descending order as follows: nitrofurantoin (80%), ofloxacin (24%), ciprofloxacin (15%), nalidixic acid (10%), cotrimoxazole (5%), and amoxicillin/clavulanic acid (2%). No isolate was susceptible to amoxicillin, gentamicin, or tetracycline. All were also found to be resistant to at least 3 commonly used drugs. All 25 isolates tested for extendedspectrum ß -lactamase (ESBC) production were found to be presumptive ESBCs producers. Conclusion: The results demonstrate the continued susceptibility of E coli to nitrofurantoin and their widespread and increasing resistance to amoxicillin, gentamicin, cotrimoxazole, ciprofloxacin, ofloxacin, and tetracycline. Nitrofurantoin is a— and, in this locale, perhaps the only— rational drug for empiric treatment of uncomplicated UTI. There is a need for a comprehensive study of the involvement of ESBC-producing E coli in UTI in this environment.

Information Technology (IT) refers to several forms of information exchange between two or more computers through any of the several methods of interconnection, principally the Internet. These technologies provide speedy, inexpensive and convenient means of communication. The diffusion of these technologies in many countries by different sectors of the economy have been found to have direct positive impact on the organization’s efficiency and have led to more rapid acceleration of development in these countries.
In developing countries Nigeria precisely, preliminary investigations show that only a few organizations in the economy have adopted the IT, but there has not been formal study to determine the level of diffusion and the factors affecting IT diffusion as well as impact on the efficiency of the organizations. This study, is therefore, designed to determine the level of diffusion in the Nigerian economy, and the impact on the operations of these organizations as well as investigating the factors responsible for the present level of diffusion of these technologies in the economy.

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