Background Hypertension is a major health problem in sub-Sahara Africa. Several studies have suggested a role of asymptomatic bacteriuria (ASB) in the aetiology of hypertension, but there is a dearth of information on this association in Africa where the burden of hypertension is high. We investigated the prevalence of asymptomatic bacteriuria, its association with hypertension and determined the antibiotic resistance patterns of implicated bacterial isolates in an urban community of Ile-Ife. Methods One hundred and seventy-four apparently healthy individuals were investigated for ASB. Relevant information was obtained from them with standard proforma. Their Blood pressure was measured with a standard mercury sphygmomanometer. All samples were processed on cysteine lactose electrolyte deficient medium and chocolate agar. Antimicrobial susceptibility testing was done using Kirby-Bauer disk diffusion technique. Results Fifty (28.7%) individuals were positive for ASB. ASB was commonly detected among the female subjects ({$\chi$}2=5.619; p-value = 0.01777), and among individuals in the age group of 50-59 years. Those that were hypertensive were two and a half times more likely to have ASB (Odd ratio=2.5; p-value=0.01369; CI=1.19-5.35). The highest percentage of hypertensive female participants with ASB was found in the age group of 30-39 years (33.3%) while among the male participants, the highest percentage was found in the age group of 60-69 years (9.5%). Escherichia coli (n=13; 26%) and Staphylococcus aureus (n=13; 26%) were the commonest organisms implicated in ASB. The majority of the isolates ({$>$}90%) were multidrug resistant. Isolates of Escherichia coli were commonly resistant to ampicillin (83.3%), ceftriaxone (72.7%) and cefepime (66.7%). Isolates of Staphylococcus aureus were all (100%) resistant to erythromycin, cloxacillin and streptomycin. All isolates were least resistant to cotrimoxazole ({$<$}8%). Conclusion Women as well as men in the age group of 50-59 years were more likely to develop ASB. ASB could be contributing to the rising incidence of hypertension in this environment. Co-occurrence of hypertension and ASB portends a grave problem for apparently healthy individuals in this environment.

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In this paper, class of second order ordinary differential equation with oscillatory solutions is considered. Byemploying the trigonometric basis function, a continuous five-step scheme known as five-step trigonometrically
fitted scheme is derived to approximate solutions to the class of considered equation. Consistency and zero
stability of the developed method were proved. Stability and convergence properties of this new scheme were
also established. The scheme so obtained is used to solve standard initial value problems with oscillatory
solutions. From the numerical results obtained, it was revealed that the proposed method performs better than
some of the existing methods in the literature.

PurposeBuilding information modeling (BIM) inclusion in education pedagogy is crucial in preparing skilled graduates for employment in the construction industry. Against this backdrop, studies on BIM education abound in architecture, engineering and construction (AEC) programmes in higher education institutions (HEIs). However, there are limited empirical studies on BIM potentials in the quantity surveying (QS) profession in HEIs, particularly in developing countries. The purpose of this study is to identify and assess the BIM drivers and benefits as important to the QS profession using an empirical approach.
Design/methodology/approach
A comprehensive literature review was conducted to identify the BIM drivers and benefits in relation to the QS profession, which was used to design a questionnaire. To capture a broad perception, a questionnaire survey was carried out which targeted the academia and final year undergraduate students from two selected universities offering QS honour degree programmes in Nigeria. Data collected were analysed using mean score, standard deviation and Mann–Whitney test.
Findings
The study identified 12 BIM drivers in relation to the QS profession and the analysis of the ranking revealed that almost all the identified BIM drivers are considered by respondents as important. The study further identified 14 BIM benefits and the analysis of the ranking indicated that all the identified BIM benefits are considered as important. The results of the Mann–Whitney test indicated a slight statistically significant difference, particularly in one of the selected universities on the ranking of the BIM drivers and benefits as important to the QS profession.
Practical implication
The findings of the study provide empirical evidence on the current perceptions of the drivers and benefits of BIM to QS academia and students as they explore the concept for the advancement of QS profession.
Originality/value
This study would provide practical insights to use BIM for QS practice. Also, this study would contribute to improving the QS graduates and professional quantity surveyors understanding of the BIM knowledge applicable to QS profession.

PurposeThe failure and abandonment of construction projects have proven to be insurmountable problems incessantly militating against the efficient performance of the construction industry in Nigeria. The complexity, technicality and a host of other project execution issues unique to multi-storey building projects do increase their susceptibility to failure and abandonment. Thus, the purpose of this paper is to examine the factors influencing failure and abandonment of multi-storey building projects in Nigeria. This is with a view to provide inferential empirical data that could enhance successful delivery of multi-storey building projects in Nigeria.
Design/methodology/approach
Primary data were used for the study. A structured questionnaire was administered on consultants and contractors’ personnel within Lagos State, Nigeria. A total of 180 copies of the questionnaire were administered ,and 134 copies which represent a combined response rate of 74.4 per cent were retrieved. The data were analysed using frequency distribution and percentages, Mean item score and factor analysis.
Findings
The factors most significant to the failure and abandonment of multi-storey building projects are inadequate funding by the client, improper planning at the pre-construction phase, structural failure in multi-storey building during construction, bankruptcy/business failure of the contractor, improper scheduling of the building project activities and failure to engage qualified professionals with technical expertise and experience. The rated factors clustered under human resources capability, planning and structural quality, contractor selection and variation, insecurity and variation, and force majeure and political risk.
Research limitations/implications
The study was limited to multi-storey building projects in Lagos State, Nigeria. Further studies could focus on specific resuscitation strategies for abandoned multi-storey building projects.
Practical implications
The study provided implications for effective project and contract management of multi-storey building projects which is very paramount to improve the delivery of complex, technical- and capital-intensive building projects in Nigeria.
Originality/value
The study provides specific implications for the management of multi-storey building projects, thereby enhancing the delivery of building projects.

Background:Traditional cardiovascular risk factors (CVRFs), which include age, gender, hypertension, diabetes mellitus, dyslipidaemia, smoking, alcohol consumption, chronic kidney disease and obesity, have been shown to be associated with atherosclerosis. We aimed to evaluate the impact of traditional CVRFs on carotid atherosclerosis (CA) in a sample of Nigerian adults.
Methods:
We examined 162 subjects with traditional CVRFs in a cross-sectional study. Demographic and clinical data, including history of hypertension, diabetes mellitus, smoking, alcohol intake and chronic kidney disease, as well as systolic and diastolic blood pressure, weight and height were collected. Serum creatinine, fasting blood glucose and lipid profiles were also determined. Carotid intima-media thickness (CIMT) and presence of carotid plaque (CP) were evaluated by high-frequency B-mode ultrasound. Chi-squared and regression analyses were carried out to determine associations between variables of CIMT and CVRF.
Results:
Increased CIMT was associated with all CVRFs (p < 0.05) except gender (p > 0.05), while CP was associated with older age, obesity, hypertension and dyslipidaemia (p < 0.05). We found prevalence of increased CIMT was 53.7%, while that of CP was 16.1%. The prevalence of CA (increased CIMT and CP) also increased with increasing number of CVRFs in the subjects. Age ≥ 50 years, hypertension, dyslipidaemia, obesity and alcohol intake explained 78.7% of variance in CIMT, while age ≥ 50 years and hypertension explained 38.0% of variance in CP.
Conclusions:
CA was associated with presence and increasing number of traditional CVRFs. A significant percentage of variance in CA was, however, unexplained by traditional CVRFs.

Barbula indica (Pottiaceae), a dioecious acrocarpous moss had never been found with sporophytes in Nigeria. The occurrence of fruiting B. indica from two populations in the Nigerian forest and derived savanna is reported for the first time. Aspects of the morphological characters of fruiting and non-fruiting plants were compared to ascertain if they are distinct species or not. The leaf and costa length were not significantly different in both types of plants. The ratios mean leaf length : mean leaf width, costa length : leaf length and apical cell size were higher in non-fruiting than in fruiting shoots. However basal and median cell lengths were higher in fruiting than non-fruiting samples. Mean shoot lengths in fruiting plants were 8.8 + 2.946 mm and 9.6 + 2.330 mm in non-fruiting samples. Non-fruiting shoots produced more axillary gemmae than fruiting ones. As all of these vegetative differences are within the morphological range of Barbula indica the fruiting and non-fruiting shoots are not distinct species.

Objective: Worldwide, the highest frequencies of APOL1-associated kidney variants are found in indigenous West Africans among whom small vessel disease (SVD) ischemic stroke is the most common stroke phenotype. The objective of this study was to investigate the association and effect sizes of 23 selected SNPs in 14 genes of relevance, including the APOL1 G1 variants, with the occurrence of SVD ischemic stroke among indigenous West African participants in the Stroke Investigative Research and Education Network (SIREN) Study. Materials and Methods: Cases were consecutively recruited consenting adults (aged 18 years or older) with neuroimaging—confirmed first clinical stroke. Stroke-free controls were ascertained using a locally validated version of the Questionnaire for Verifying Stroke-Free Status (QVSFS). Logistic regression models adjusting for known vascular risk factors were fitted to assess the associations of the 23 SNPs in rigorously phenotyped cases (N = 154) of SVD ischemic stroke and stroke-free (N = 483) controls. Results: Apolipoprotein L1 (APOL1) rs73885319 (OR = 1.52; CI: 1.09-2.13, P-value =.013), rs2383207 in CDKN2A/CDKN2B (OR = 3.08; CI: 1.15-8.26, P –value =.026) and rs2107595 (OR = 1.70; CI: 1.12-2.60, P-value =.014) and rs28688791 (OR = 1.52; CI: 1.03-2.26, P-value =.036) in HDAC9 gene were associated with SVD stroke at 0.05 significance level. Polymorphisms in other genes did not show significant associations. Conclusion: This is the first report of a specific association of APOL1 with a stroke subtype. Further research is needed to confirm these initial findings and deepen understanding of the genetics of stroke in people of African ancestry with possible implications for other ancestries as all humans originated from Africa.

Background: Traditional cardiovascular risk factors (CVRFs), which include age, gender, hypertension, diabetes mellitus, dyslipidaemia, smoking, alcohol consumption, chronic kidney disease and obesity, have been shown to be associated with atherosclerosis. We aimed to evaluate the impact of traditional CVRFs on carotid atherosclerosis (CA) in a sample of Nigerian adults. Methods: We examined 162 subjects with traditional CVRFs in a cross-sectional study. Demographic and clinical data, including history of hypertension, diabetes mellitus, smoking, alcohol intake and chronic kidney disease, as well as systolic and diastolic blood pressure, weight and height were collected. Serum creatinine, fasting blood glucose and lipid profiles were also determined. Carotid intima-media thickness (CIMT) and presence of carotid plaque (CP) were evaluated by high-frequency B-mode ultrasound. Chi-squared and regression analyses were carried out to determine associations between variables of C1MT and CVRF. Results: Increased CIMT was associated with all CVRFs (p < 0.05) except gender (p > 0.05), while CP was associated with older age, obesity, hypertension and dyslipidaemia (p < 0.05). We found prevalence of increased CIMT was 53.7%, while that of CP was 16.1%. The prevalence of CA (increased CIMT and CP) also increased with increasing number of CVRFs in the subjects. Age > 50 years, hypertension, dyslipidaemia, obesity and alcohol intake explained 78.7% of variance in CIMT, while age > 50 years and hypertension explained 38.0% of variance in CP. Conclusions: CA was associated with presence and increasing number of traditional CVRFs. A significant percentage of variance in CA was, however, unexplained by traditional CVRFs.