EVALUATION OF BILGE WATER-INDUCED PLANT GENOTOXICITY USING RANDOMLY AMPLIFIED POLYMORPHIC DNA (RAPD) - Olorunfemi D.I.; Okieimen, E. A; Muokebe, I. (Ife Journal of Science, 2015)

EVALUATION OF CONTAMINATION CHARACTERISTICS OF WATER AND STREAM SEDIMENTS AT THE VICINITY OF AWOTAN DUMPSITE IN IBADAN, SOUTHWEST NIGERIA - Ogunseiju, P.; Ajayi, T. R.; Olarewaju, V. O (IJS, 2015)

EVALUATION OF CONTAMINATION CHARACTERISTICS OF WATER AND STREAM SEDIMENTS AT THE VICINITY OF AWOTAN DUMPSITE IN IBADAN, SOUTHWEST NIGERIA - Ogunseiju, P.; Ajayi, T. R.; Olarewaju, V. O (IJS, 2015)

Evaluation of growth performance and carcass composition of Dutch Clarias fingerlings fed varying crude protein diet - “F. P. Asuwaju”; “A. N. Olanrewaju”; “O. K. Kareem”; “O. Orisasona”; “R. A. Obande”; “G. O. Omorodion” (30th Annual Conference of the Fisheries Society of Nigeria (FISON), 2015)

AN EVALUATION OF SORGHUM BICOLOR (Linn.) MOENCH LEAF SHEATH EXTRACT IN HIGH FAT DIET-INDUCED OBESE RATS - Ugbaja, R. N.; Owoeye, F. D.; Dedeke, G. A; Akinloye, O. A (IJS, 2015)

Evaluation of the Intensity of the Daytime Surface Urban Heat Island: How can remote sensing help?, - A. Ayanlade; Jegede, O. O. (International Journal of Image and Data Fusion: Remote Sensing Journal, 2015)
This study aimed at using remote sensing methodology to assess the daytime surface urban heat island (SUHI) in Lagos metropolis. Several studies have examined the SUHI, using point data from meteorological stations. However, it has been shown in the literature recently that it is practically impossible to accurately value the intensity of SUHI from ground meteorological measurement due to heterogeneity and complexity of surface temperature over land. Therefore a time series of Landsat data, from 1984 to 2012, were used in the present study to assess spatial and temporal variability in the contribution of source and sink landscape to daytime SUHI in Lagos. This study uses remote sensing methods because Lagos has a strong heterogeneity of land surface characteristics; with several drainage, vegetation, built-up and soil between the coast and mainland, thus the land surface temperature (LST) changes rapidly in space and time. The results from this study show differences in the contribution of source and sink landscape to SUHI. The main findings from the results show that source landscape contributes positively to the intensity of SUHI in Lagos metropolis. The results show a general increase in mean LST during the periods of study from 1984 to 2012. The north-west (NW) zone of Lagos has highest LST compared to other zones. In 1984, the mean LST of NW zone was 300.53 K, but increased to 301.85 K in 2000 and 302.85 K in 2012. Although contributions from the landscapes differ by zones and time, much more intensified LST was noted in the NW zone of the city. The study find out that change in landcover has been the most important driver of intensified SUHI in Lagos metropolis. NW zone recorded the highest increased in built-up area throughout the years: 320.32 km2 in 1984, 535.28 km2 in 2000 and 630.70 km2 in 2012. This study demonstrates therefore that it is possible to assess spatial distribution and long-term temporal evolution of the LST in urban area, using remote sensing data. Also the results shows that remote sensing methods offer possibility for measuring LST over complete spatially averaged rather than point values. The results from this study further our understanding that not only the SUHI is frequent to cities in developed countries, but the effects are also obvious in several urban settlements in tropical countries.

EXAMINING THE EFFICACY OF AN ITERATIVE MEASUREMENT ERROR ADJUSTMENT TECHNIQUE ON THE ADEQUACY OF A 2-LEVEL MODEL - Imande M.T (IJS, 2015)

FORAMINIFERAL BIOSTRATIGRAPHY AND PALEOENVIRONMENTAL ANALYSES OF SEDIMENTS FROM FOLU-1 BOREHOLE, IBEJU-LEKKI, LAGOS STATE, NIGERIA - Fadiya, S. L.; Ojoawo, E. A. (Ife Journal of Science, 2015)

Frontiers in Environmental Research and Sustainable Environment in the 21st Century - A. S. Gbadegesin; E. B. Eze; Oluwagbenga, O.I. Orimoogunje; O. A. Fashae (Ibadan University Press, 2015)
The primary object of this book is to present current issues and problems relating to environmental sustainability and to discuss them as elements of the earth’s surface. This book is timely because of the widespread interest in geographical approaches to solving environmental problems. However, the celebration of the two Giants of Geography – Emeritus Professor Adetoye Faniran and Professor Olusegun Areola from the Department of Geography, University of Ibadan, Nigeria afforded scholars to share their interest especially because of the opportunity to celebrate the erudite Giants by holding a National Colloquium on Frontiers in Environmental Research and Sustainable Environment in the 21st Century. The collections of articles in this book result from the scholars’ concerns to evaluate environmental geographical applicability to environmental management in several natural resource fields. The study of such complexes requires more than one individual. This has led to the concept of interdisciplinary research which involves diversity of skills and specialties. Environmental geography has for some time been prominent in research and management studies, but only a few components have been measured or considered in most instances.

FUEL WOOD CONSUMPTION AND SPECIES DEGRADATION IN SOUTH-WESTERN NIGERIA: THE ECOLOGICAL RELEVANCE - Oluwagbenga, O.I. Orimoogunje; Asifat, T.J (Journal of Landscape Ecology, 2015)

Generalized Osborn loops of order 4n - A. Isere; J.O. Adeniran; T. G. Jaiyeola (Acta Universitatis Apulensis Mathematics Informatics, 2015)

Generalized right central loops - T. G. Jaiyeola (Afrika Matematika, 2015)

A Geo-Informatics Technique for the Management of Meningitis Epidemic Distributions in Northern Nigeria - Ayanlade, O. S.; DO Baloye; MO Jegede; A. Ayanlade (Information Resources Management Journal, 2015)
This study aims at examining and mapping the spatiotemporal distribution of meningitis epidemic, in relation to climate variability, using GIS and Remote Sensing techniques. Using the northern part of Nigeria as a case study, data on meningitis epidemic were obtained from the archive of National Bureau of Statistics, Nigeria for the periods between 1998 and 2013. The data were updated with collection from Nigeria Demographic and Health Survey (NDHS). Also, Nigerian Ministry of Health has compiled consistent statistics on meningitis incidence for the periods. A meningitis distribution map was derived from an environmentally-driven form of predicted probability of epidemic experience as it is in International Research Institute for Climate and Society (IRI) Database. The results showed that Meningitis Epidemic is very high during months with low rainfall. Thus, seasonality of rainfall and temperature are important determinants of Meningitis Epidemic incidence in the Northern part of Nigeria. Therefore, it can be confirmed, as cited in some literatures, that the distribution of the epidemics has a strong association with the environment, especially climate variability. Although meningitis surveillance systems in Nigeria have improved, they still fall short of the sensitivity required to demonstrate incidence changes in vaccinated and non-vaccinated cohorts and complementary approaches may be needed to demonstrate the impact of the vaccines. There is however, a need for a new technology and innovation like an integrated GIS, and other environmental modeling system, to allow health practitioners as well as policy makers, for better management, productivity and profitability.

Geo-Spatial Mapping of Air Pollution in Benin City, Nigeria - Verere Sido Balogun; Oluwagbenga, O.I. Orimoogunje (Journal of Geography, Environment and Earth Science International, 2015)

GEOCHEMICAL ASSESSMENT OF THE IMPACT OF AN ACTIVE OPEN DUMPSITE ON SOIL IN IBADAN, SOUTHWESTERN NIGERIA - Ogunseiju, P.; Ajayi, T. R.; Olarewaju, V. O (IJS, 2015)

GEOELECTRIC INVESTIGATION OF A SITE FOR A PROPOSED AIRPORT IN EBONYI STATE, SOUTHEAST NIGERIA. - Okiyi, I.M; M. O. Olorunfemi; Ojo, J. S.; Akintorinwa, O.J.; Bayode, S. (Ife Journal of Science, 2015)

Geoinformatics in Eco-climatic Studies - A. Ayanlade; MO Jegede; P.B. Borisade (In Mehdi Khosrow-Pour (ed), Information Science and Technology, Third Edition, 2015)
Background Geoinformatics is a modern technology that provides accurate means of measuring the extent and pattern of changes, and other related information about environment (Boakye et al., 2008). The term “Geoinformation” consists of two main words: “Geo” which means earth’s surface or the environment; and “informatics” stands for fact about something. Thus, Geoinformation is the science and technology of communicating the evidences about the state of the earth’s surface. It is known for technological robustness to assess spatial and temporal change occurring on the earth’s surface (Yang & Liu, 2005; Ehlers, 2008). In the recent years, Geoinformatics has been used to provide electronic representation about earth’s surface and man’s interaction with the earth. Geoinformatics has emerged in the last two decades as an exciting multi-disciplinary endeavour, spanning such areas as Geography, Cartography, Remote Sensing, Image Processing, Environmental Sciences and Computer Aspects of environmental studies. In general, the science and technology of Geoinformatics encompasses application of remote sensing and GIS data and methodology. GIS is an acronym that stands for Geographic Information Systems while the remote sensing data are those data collected through various devices without human (researcher) contact with field. GIS, in actual sense, is not a new development, it is only recently that it has gained widespread acceptance as a tool to assess both spatial and non-spatial issues. GIS was initially referred to as the management of information with a geographic component primarily stored in vector form with associated attributes. This definition quickly became too limiting with advances in software and recent digital ideas about earth. GIS involves spatiotemporal data analysis using software, hardware, people and approaches to acquire, store, update and manipulate for presenting information about the human environment. GIS could be seen as a digital computing environment and human interactions with the environment. For environmental change analysis, GIS uses both remote sensing and non-remote sensing data. Non-remote sensing data may include field observation, topographic, geological and edaphic data. It may also include terrain data, as well as socio-economic survey data, and reports relating to human environmental relation. Though non-remote sensing data are those data acquired by other means than remote sensing approach, they are sometimes used in Geoinformatics analysis, for identification and interpretation of environmental features and their significant change over time (Campbell 2002). In general, it has been shown in several other recent studies that Geoinformatics is not only good for preparing precise environmental change assessment, but also for observing changes at regular intervals of time, it is cost and time effective (Kreuter et al., 2011; Ahmad, 2012; Aguirre-Gutiérrez et al., 2012; Avitabile et al., 2012).

GEOPHYSICAL AND HYDROGEOCHEMICAL EVALUATION OF A SPRING IN ADO-EKITI,SOUTH-WESTERN NIGERIA - Afolabi O.; Oyawale A. A.; Olorunfemi A. O. (Ife Journal of Science, 2015)

GEOSPATIAL ANALYSIS OF TEMPORAL DIFFERENCE IN ECOSYSTEMS OF COASTAL AREAS AND THE EFFECTS ON RURAL COMMUNITIES IN NIGERIA - Fabiyi Oluseyi O. (Ife Journal of Science, 2015)

GEOTECHNICAL INVESTIGATION OF SOME FAILED SECTIONS ALONG OSOGBO-AWO ROAD, OSUN-STATE, SOUTHWESTERN NIGERIA. - Oyelami; Adebayo Charles and Alimi; Sodiq Abiodun (Ife Journal of Science, 2015)

Green Buildings as Panacea for Sustainable Property Management Practice in Nigeria - Ogunba, O. A.; O. D. Ajayi; Ajayi, C. A. (Proceedings of Environmental Design and Management International Conference, Obafemi Awolowo University, Ile Ife, 2015)

GROUNDWATER RECHARGE USING BASEFLOW RECESSION ANALYSIS IN SOUTHWESTERN NIGERIA - Idowu, O. A.; Martins, O.,; Oluwasanya O.; Awomeso, J. A.; Olaoye, O. A. (Ife Journal of Science, 2015)

The Growth and Mineral Utilization of Clarias gariepinus Fingerlings Fed Phytase-Supplemented Toasted Lima Bean (Phaseolus Lunatus) diets - “O. Orisasona”; “E. K. Ajani” (Journal of Aquaculture Research and Development, 2015)

HAEMATOLOGY AND SERUM BIOCHEMISTRY OF F AND F PIGS PRODUCED BY 1 2 ASF- RECOVERED PIGS - Adeoye, A.A.; Udoh, J.E.; Rotimi, E. A; Ikeobi, C.O.N; Adebambo, O.A. (Ife Journal of Science, 2015)

HIV self-testing in Nigeria: Public opinions and perspectives - Brown, B; Folayan, MO; Imosili, A; Durueke, F; Amuamuziam, A (Global Public Health, 2015)

HIV/AIDS pandemic and current practice among Paediatric Surgeons in Nigeria - Sowande, O. A.,; Talabi, A.,; Olowookere, S.,; Adejuyigbe, O.,; Owotade F. (Afr J Med Med Sci, 2015)

Holomorph of generalized Bol loops II - T. G. Jaiyeola; B.A. Popoola (Discussiones Mathematicae-General Algebra and Applications (doi:10.7151/dmgaa.1234), 2015)

Holomorphy of Osborn loops - A. Isere; J.O. Adeniran; T. G. Jaiyeola (Analele Universitatii De Vest Din Timisoara, Seria Matematica-Informatica, 2015)

Identification, Handling and Eradication of Corruption in Teaching, Research and Publication in Higher Institutions in Nigeria - Adeyemi, B. A. (Education Today: Imperatives of Quality Assurance, 2015)

The Impact of Information and Communication Technology on Real Estate Agency in Lagos Metropolis - Ajayi, C. A. (Obafemi Awolowo University, 2015)

The Impact of Pan-Africanism and Nationalism on the Evolution of Modern Visual Arts in Nigeria - Babasehinde A Ademuleya (Journal of Art and Design Studies, 2015)
The paper examined the political and philosophical ideologies of the Pan-Africanism and Nationalism movements and their impact on the 20th century art of Africa with a particular reference to Nigeria. It opined that, while the foundation of modern arts in African could largely be attributed to Africans’ embrace of Western education and life style, the African and Black descents’ concept of Pan-Africanism and Nationalism (home and abroad) which fuelled the young African elites’ renewed appreciation of interest in African culture and quest for African identity, also stimulated and fed the pre/post independent visual arts. The paper argued that the African nationalists’ agitation for political freedom from colonial powers within the continent and that of Africans in Diaspora’s struggle for liberation in the West and Europe which provoked the political vibes of the 1950s and 60s was indeed instrumental to the radical invigoration of the evolving modern visual arts of the continent in general and that of Nigeria in particular. It submitted that the Pan-Africanism and Nationalism movements’ ideals actually midwife the ‘Zarianist’ revolution and the reinvention of the concept of synthesis as evident in the Zaria Society of Art’s natural synthesis theory as well as the post independent’s emergence of art movements and stylistic art schools.

The Impact of Strategic Human Resource Management on Competitiveness of Small and Medium-scale Enterprises in the Nigerian Hospitality Industry - OLOGUNDE Adedoyin, MONDAY James, JAMES-UNAM Folasade (African Research Review,, 2015)

Impact of Tax Reforms on Revenue Generation in Lagos State: A Time Series Approach - ASAOLU Taiwo, MONDAY James, DOPEMU Samson (Research Journal of Finance and Accounting,, 2015)

IMPACT OF URBAN ACTIVITIES ON GROUNDWATER QUALITIES IN ABEOKUTA SOUTHWESTERN, NIGERIA - Laniyan, T. A; Ajibade, O. M; Bayewu, O. O.; Oshomoji, A. O. (Ife Journal of Science, 2015)

Induced collaborative engagement for a “solution-to-question” model using remote experimental laboratories as a tool - Obasegun T Ayodele; Kehinde, Lawrence Olakunle; Olawale Akinwale, (122nd ASEE Annual Conference & Expostion, 2015)

Information and Communication Technology: A Tool for Health Care Delivery in Nigeria - Peter Adebayo Idowu (Computing in Research and Development in Africa: Benefits, Trends, Challenges and Solutions, 2015)

Inheritance of purple pigmentation in Carica papaya Linn. (Caricaceae) (International Journal of Plant Research, 2015)

INTEGRATED GEOPHYSICAL INVESTIGATION OF YEMOO GROVE ARCHAEOLOGICAL SITE IN ILE-IFE, OSUN STATE, SOUTHWEST NIGERIA. - M. O. Olorunfemi; Ogunfolakan, B.A; Chouin, G.L.; Oni, A.G. ; Okunubi, M. O.; Akinwumiju, A.S (IJS, 2015)

INVESTIGATION OF RELATIONSHIPS BETWEEN GEOELECTRIC AND HYDRAULIC PARAMETERS IN A QUATERNARY ALLUVIAL AQUIFER IN YENAGOA, SOUTHERN NIGERIA - Okiongbo, K. S; Oborie, E. (Ife Journal of Science, 2015)

INVESTIGATIONS INTO THE ANTIOXIDANT AND ANTI-INFLAMMATORY POTENTIALS OF THE ETHANOLIC EXTRACT OF CITRUS SINENSIS, LINN. (SWEET ORANGE) STEM-BARK - Asaolu, F. T.; Areola J. O.; Tijani A. S (IJS, 2015)

Ionospheric time-delay over Akure using global positioning system observations - Bolaji, O. S.; Ixang, P. A.; Oladosu, O. R.; Koya, Femi; Fayose, R. S.; Rabiu, B. A. (Acta Geophysica, 2015)

A Journey Through the Beautiful World of Differential Equations (Inaugural Lecture) - Adesina, O.A. (Obafemi Awolowo University Press, 2015)

Length-weight Relationship and Condition factor of Chrysichythys nigrodigitatus and Schilbe mystus in Erelu Lake, Oyo State, Nigeria - "O. K. Kareem"; "A. N. Olanrewaju"; "O. Orisasona" (Journal of Fisheries & Livestock Production, 2015)

Level of Income, Marital status and Home background Variables as Predicators of Criminal Traits among Nigerian Prisoners - Adeyemi B. A. (Journal of Emerging Trends in Educational Research and Policy Studies, 2015)

LIFE HISTORY CHANGE IN SILVER CATFISH, CHRYSICHTHYS NIGRODIGITATUS, FAMILY BAGRIDAE, IN OGUN STATE COASTAL ESTUARY, NIGERIA - Waidi O. Abdul (IJS, 2015)

Local Community-Based Clustering pattern and Sexual Behaviour of Persons with HIV/AIDS in Different Residential Densities of a Nigerian Semi-Rural Region - Abegunde, A.; Adedigba, M.; Ogunmodede, E.; Mobolaji, J (Ife Journal of Behavioural Research, 2015)

Local Content Policy, Human Capital Development and Sustainable Business Performance in the Nigerian Oil and Gas Industry - MONDAY James,; (Journal of Management and Sustainability, 2015)

MEASUREMENT OF THE SPECIFIC AND THE APPARENT MOLAR VOLUMES OF SOME EVEN CHAIN LENGTH FATTY ACIDS IN ETHANOL - Akanni, M. S.,; Abdul, E. O.,; A.S. Adekunle; J.A.O. Oyekunle (ife journal of science, 2015)

MEDICINAL PROPERTY AND TOXICOLOGICAL ASSESSMENT OF THE AQUEOUS EXTRACT BALANITES AEGYPTIACA MESOCARP. - Wudil, A. M.; Sule, M. S.; Atiku, M. K (IJS, 2015)

A METHOD DEVELOPED FOR THE EXTRACTION, DETECTION AND QUANTIFICATION OF ORGANOPHOSPHORUS PESTICIDE IN AQUEOUS MEDIA - Justina Ukpebor (Ife Journal of Science, 2015)

Mobility and gender aspects of hospital trips of the urban elderly in Ilesa, Nigeria - M.O.Olawole (Ife PsychologIA, 2015)
Accessibility to health care facilities is one characteristic that have the potential to impact the health and well-being of the elderly. Using data from a multistage sample survey of 378 elderly, this study examines intra- urban mobility and gender differences in hospital trips of elderly in the city of Ilesa, South-western, Nigeria. Data were analysed using descriptive statistics, Chi-square and ANOVA. The analysis reveals similarity in gender trip rates to hospitals - 63.14% of elderly men and 66.29% of elderly women of the samples visited hospitals for medical treatment during the period under study. Overall, occasional trips frequency accounts for 96.71% of the trips to hospitals. The findings show significant gender differences in trip frequencies, travel distance and mode choices of the elderly. The research results reinforce the importance of intra urban and gender variations in travel characteristics of the elderly to hospitals.

Modelling the impact and cost-effectiveness of combination prevention amongst HIV serodiscordant couples in Nigeria - Mitchell, KM; Lepine, A; Terris-Prestholt, F; Torpey, K; Khamofu, H; Folayan, MO; Musa, J; Anenih, J; Sagay ,AS; Alhassan, E; Idoko, J; Vickerman, P (AIDS Journal, 2015)

Morphological and cytological studies of Euphorbia hyssopifolia L. and Euphorbia heterophylla L. from Ile-Ife, Nigeria - A. O. Bolaji; C.B. Olojede; A.A. Famurewa; Faluyi, J O (Nigerian Journal of Genetics, 2015)

MULTI-ELEMENTAL ANALYSIS AND SOURCE APPORTIONMENT OF URBAN AEROSOLS IN A LOW DENSITY RESIDENTIAL AREA: A CASE STUDY OF IKOYI LAGOS NIGERIA. - Ezeh , G. C.,; I. B. Obioh; O.I Asubiojo (ife journal of science, 2015)

New algebraic properties of middle Bol loops - T. G. Jaiyeola; S. P. David; Y. T. Oyebo (Societatea Română de Matematică Aplicată si Industrială Journal (ROMAI J.), 2015)

ON THE PERFORMANCE OF AUTOREGRESSIVE MOVING AVERAGE POLYNOMIAL DISTRIBUTED LAG MODEL - J.F. Ojo; Aiyebutaju, M. O. (Ife Journal of Science, 2015)

Online Road Traffic Accident Monitoring System for Nigeria - Peter Adebayo Idowu; Kehinde Williams; Emmanuel Olonade (Transactions on Networks and Communications, 2015)

Online Spatial Cancer Registry System for Nigeria. - Peter Adebayo Idowu; Bunmi Alonge; Olusegun Ajibola Sarunmi (Journal of Biomedical Engineering and Medical Imaging, 2015)

Oral findings in chronic kidney disease: implications for management in developing countries - Oyetola, E.O.,; Owotade, J. F.,; Agbelusi, G. A.,; Fatusi, O.,; Sanusi, A.A (BMC Oral Health, 2015)

PALYNOLOGICAL SURVEY OF AIR-BORNE POLLEN AND SPORES IN THE UNIVERSITY OF LAGOS, AKOKA CAMPUS, SOUTHWESTERN NIGERIA - Ajikah L.,; Ogundipe O.; Bamgboye O (IJS, 2015)

Pan-Africanism and the Black Festivals of Arts and Culture: Today’s Realities and Expectations - Ademuleya, B. A; Fajuyigbe, M. O (Journal of Humanities and Social Science (IOSR-JHSS), 2015)
This paper attempted a review of the Black Festivals of Arts with a view to highlighting how the achieved cultural integration through the arts could be further explored for today’s realities and expectations. It attributed the first two editions of the Festivals of Blacks arts and culture which owed much to the ideologies of the Pan-Africanism and Negritude that preceded them, to the laid legacies that have continued to serve as strong reference points in the discussion of Africans and African descent relationship. It argued that apart from providing an unusual forum that brought to light the diverse contributions of Blacks and African peoples to the universal currents of thought and arts, both editions drew attentions to the expected relationship between the continental Africans and their offspring in the Diaspora. The paper observed that the events reassert the African identity thus creating the platform for continental Africa and the Diaspora to move through the borders of nation state and the psychosocial borders of racism which is central to all Pan-Africanist freedom movements. It however noted that forty eight years after the maiden edition of the festival (FESMAN) and thirty seven years after the second (FESTAC), the achieved cultural integration seem yet to translate into much expected economic, political, educational, philosophical and technological advancements of African nations and that of the Diaspora.

PARTICLE SIZE ANALYSIS OF SOME SIDEWALL CORES FROM KU-1 WELL, OFFSHORE BENIN BASIN, NIGERIA. - Fadiya, S. L. (Ife Journal of Science, 2015)

Pattern and Prevalence of Underweight,Overweight and obesity among young adult Nigerians - Asafa M A; Ogunlade O (American Journal of Biomedical and Life Sciences, 2015)

Pèrègún y otras fabulaciones de mi tierra. Edición - Ayoh'OMIDIRE, Félix (Editorial Arte y Literatura, 2015)

PERFORMANCE EVALUATION FOR DARCY FRICTION FACTOR FORMULAE USING COLEBROOK-WHITE AS REFERENCE (Ife Journal of Science, 2015)

Personality profiles and psychopathology among students exposed to dating violence at the Obafemi Awolowo University, Ile-Ife - Mapayi, Boladale; Oladimeji, Yetunde; Akinsulore, Adesanmi; Aloba, Olutayo; Ibigbami, Olanrewaju (Journal of interpersonal violence, 2015)
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Pharmacogenetics of pregnancy-induced changes in efavirenz pharmacokinetics - Adeniyi Olagunju; Bolaji, Oluseye; Amara, Alieu; Laura Else; Okafor, Ogechi; Ebunoluwa Adejuyigbe; Johnson Oyigboja; David Back; Khoo, Saye; Andrew Owen (Clinical Pharmacology & Therapeutics, 2015)
Pregnancy-induced physiological changes alter many drugs' pharmacokinetics. We investigated pregnancy-induced changes in efavirenz pharmacokinetics in 25 pregnant and 19 different postpartum women stratified from 211 HIV-positive women in whom a preliminary pharmacogenetic study had been undertaken. Despite significant changes in CL/F during pregnancy (42.6% increase; p = 0.023), median (range) Cmin was 1000 ng/ml (429-5190) with no significant change in Cmax (p = 0.072). However, when stratified for CYP2B6 516G>T (rs3745274) genotype, efavirenz AUC0-24, Cmax and Cmin were 50.6% (p = 0.0013), 17.2% (p = 0.14) and 61.6% (p = 0.0027) lower during pregnancy (n = 8) compared with postpartum (n = 6) in 516G homozygotes, with values of 25,900 ng.h/ml (21,700-32,600), 2640 ng/ml (1260-3490) and 592 ng/ml (429-917), respectively, and CL/F was 100% higher (p = 0.0013). No changes were apparent in CYP2B6 516 heterozygotes (14 pregnant versus 7 postpartum). The clinical implications of these findings warrant further investigation. This article is protected by copyright. All rights reserved.

Pharmacogenetics of pregnancy-induced changes in efavirenz pharmacokinetics - Adeniyi Olagunju; Bolaji, Oluseye; Amara, Alieu; Laura Else; O. Okafor; Ebunoluwa Adejuyigbe; J Oyigboja; David Back; Khoo, Saye; Andrew Owen (Clinical Pharmacology and Therapeutics, 2015)
Pregnancy-induced physiological changes alter many drugs' pharmacokinetics. We investigated pregnancy-induced changes in efavirenz pharmacokinetics in 25 pregnant and 19 different postpartum women stratified from 211 HIV-positive women in whom a preliminary pharmacogenetic study had been undertaken. Despite significant changes in CL/F during pregnancy (42.6% increase; P = 0.023), median (range) Cmin was 1,000 ng/mL (429-5,190) with no significant change in Cmax (P = 0.072). However, when stratified for CYP2B6 516G>T (rs3745274) genotype, efavirenz AUC0-24 , Cmax and Cmin were 50.6% (P = 0.0013), 17.2% (P = 0.14), and 61.6% (P = 0.0027) lower during pregnancy (n = 8) compared with postpartum (n = 6) in 516G homozygotes, with values of 25,900 ng.h/mL (21,700-32,600), 2,640 ng/mL (1,260-3,490), and 592 ng/mL (429-917), respectively, and CL/F was 100% higher (P = 0.0013). No changes were apparent in CYP2B6 516 heterozygotes (14 pregnant vs. 7 postpartum). The clinical implications of these findings warrant further investigation.

POTENTIALS OF MICROORGANISMS ASSOCIATED WITH PLANTAIN PEELS IN THE LAGOS METROPOLIS FOR BIODEGRADATION AND BIOCONVERSION. - Ogunyemi, A. K.; Buraimoh, O. M.; Ogundele, M. T.; Adigun, J. A.; Olumuyiwa, E. O.; Amund, O. O.; Okpuzor J.; Odetunde S. K.; Ehinmore I. O.; Avungbeto M. O. (IJS, 2015)

PRE-CONSTRUCTION GEOELECTRICAL AND GEOTECHNICAL ASSESSMENT OF AN ENGINEERING SITE AT ALAPERE/AGBOYI, LAGOS, NIGERIA - Oladele, S; Oyedele, K. F.; Dinyo, M. O. (IJS, 2015)

Prediction Model for Likelihood Of Infertility in Women Using Multi-Layer Perception - Peter Adebayo Idowu; Sarunmi Olusegun Ajibola; Jeremiah Ademola Balogun (Application of Information and Communication Technology for Training, Research and Administration, 2015)

Prediction Model for Likelihood of Survival of Sickle-Cell Anaemia (SCA) among Paediatric Patients using Fuzzy Logic - Peter Adebayo Idowu; T.A. Aladekomo; K.O.Williams; J. A. Balogun (Transactions on Networks and Communications, 2015)

PRELIMINARY ASSESSMENT OF SOURCE ROCK POTENTIAL AND PALYNOFACIES ANALYSIS OF MAASTRICHTIAN DARK SHALE, SW ANAMBRA BASIN - Edegbai, A. J.; Emofurieta, W. O. (Ife Journal of Science, 2015)

The prevalence and pattern of deciduous molar hypomineralization and molar-incisor hypomineralization in children from a suburban population in Nigeria - Temilola, DO; Folayan, MO; Oyedele, TO (BMC Oral Health, 2015)

PREVALENCE OF HIGH BLOOD PRESSURE AMONG YOUNG ADULTS IN ILE-IFE, NIGERIA - Asafa M A; Ogunlade O (International journal of Analytical, Pharmaceutical and Biomedical Sciences, 2015)

Prevalence, early childhood caries risk indicators in preschool children in sub-urban Nigeria - Folayan, MO; Kolawole, KA; Oziegbe, EO; Oyedele, T; Oshomoji, OV; Chukwumah, NM; Onyejaka, N (BMC Oral Health, 2015)

Prevalence, pattern and severity of molar incisor hypomineralisation in 8 to 10 year-old children in Ile-Ife, Nigeria - Oyedele, TA; Folayan, MO; Adekoya-Sofowora, CA; Oziegbe, EO (European Archives of Paediatric Dentistry, 2015)

Prioritization of healthcare workers for experimental Ebola therapeutic would exacerbate existing inequalities. - Folayan, MO; Haire, B (Developing World Bioethics, 2015)

PURIFICATION AND CHARACTERIZATION OF RHODANESE FROM THE HEPATOPANCREAS OF GARDEN SNAIL, Limicolaria flammea. - R.E. Okonji; James, I. E.; Madu, J. O.; Fagbohunka, B. S.; Agboola, F. K. (Ife Journal of Science, 2015)

The Relevance of Green Building Practice in Emerging Markets: A Perceptual Analysis of Commercial and Industrial Building Users in Ibadan, Nigeria - Olaleye, A.; Ayodele, T.O; Komolafe, M. O (Journal of Sustainable Real Estate, 2015)

The role of electrocardiogram in the diagnosis of dextrocardia with mirror image atrial arrangement and ventricular position in a young adult Nigerian in Ile-Ife: a case report - Ogunlade O; Ayoka A O; Akomolafe R O; Akinsomisoye O S; Irinoye A I; Ajao A; Asafa M A (2015)

Salivary Flow Rates of Nigerian Patients with Chronic Kidney Disease: A Case-control Study - Oyetola, E.O.,; Owotade, J. F.,; Agbelusi, G. A.,; Fatusi, O.,; Sanusi, A., (J Contemp Dent Pract, 2015)

Saying 'No' to PrEP research in Malawi: what constitutes 'failure' in offshored HIV prevention research? - Peterson, K; Folayan, MO; Chigwedere, E; Nthete, E (Anthropology Medicine, 2015)

SEQUENCE STRATIGRAPHY AND STRUCTURAL ANALYSIS OF THE EMI FIELD, OFFSHORE DEPOBELT, EASTERN NIGER DELTA BASIN, NIGERIA - Oresajo, B. S.; Adekeye, A. O.; Haruna, K. A. (Ife Journal of Science, 2015)

SOIL ALGAE: A CASE STUDY OF TWO VEGETABLE FARMLANDS IN LAGOS AND OGUN STATES, SOUTHWEST NIGERIA. - Adesalu, T. A.; Olugbemi, O. M. (IJS, 2015)

SOME STOCK PARAMETERS OF ELOPS LACERTA DURING ESTUARINE PHASE OF LIFE HISTORY - Abdul, W. O; Omoniyi, I. T.; Adekoya, E. O; Daniel, O. S; Olowe, O.S. (Ife Journal of Science, 2015)

SPATIAL ANALYSIS OF AGRICULTURAL LANDUSE CHANGE IN ASABA, SOUTHERN NIGERIA - Enaruvbe, G. O.; Atedhor, G. O. (Ife Journal of Science, 2015)

A Spatial Data Model for Environmental Health Surveillance System in Nigeria - Peter Adebayo Idowu (Journal of Research in Science, Technology, Engineering and Management, 2015)

SPATIAL DISTRIBUTION OF TRACE ELEMENT OF ALA RIVER'S SEDIMENTS, AKURE, SOUTHWESTERN NIGERIA - Asowata I.T; Badejo O.O; Onifade, O. M; Olukoya F.F (Ife Journal of Science, 2015)

Stability, Boundedness, and Existence of Periodic Solutions to Certain Third-Order Delay Differential Equations with Multiple Deviating Arguments - A.T. Ademola; Ogundare, B.S.; Ogundiran, M.O; Adesina, O.A. (International Journal of Differential Equations, 2015)

Stakeholder engagement with Ebola therapy research in resource limited setting - Folayan, MO; Haire, B; Peterson, K; Yakubu, A; Brown, B (BMC Infectious Disease, 2015)

STATISTICAL EVALUATION OF MATHEMATICAL METHODS IN SOLVING LINEAR THEORY PROBLEMS: DESIGN OF WATER DISTRIBUTION SYSTEMS - I.A. Oke; Ismail, A.; Lukman , S.; Adie, D.B.; O. O. Adeosun; Umaru, A. B.; Nwude, M.O. (Ife Journal of Science, 2015)

Strategic Management and Corporate Performance: A Resource-Based Approach - MONDAY James, ALADERAJI Tobi (Ife Journal of Humanities and Social Sciences, 2015)

Strategic Management and Firm performance: A Study of Selected Manufacturing Companies in Nigeria - MONDAY James, AKINOLA Grace, OLOGBENLA Patrick, ALADERAJI Tobi (European Journal of Business and Management,, 2015)

Strategies for oral health research in Africa and the Middle Eastern region - Naidoo, S; Dimba, E; Yengopal, V; Folayan, MO; Akpata, ES (Advance Dental Research, 2015)

STUDIES OF SOME MORPHOLINO- AND METHYLPIPERAZIN-1-YL MANNICH LIGANDS AND THEIR Cu(II) AND Ni(II) COMPLEXES - Ayeni, A. O.; G.O. Egharevba (IJS, 2015)

STUDY OF HEAVY METALS IN THE GASTROPOD, PACHYMELANIA AURITA (MULLER, 1774), SEDIMENT AND WATER FROM OLOGE LAGOON, SOUTHWESTERN NIGERIA - Samuel, O. B.; Osibona, A. O.; Chukwu, L. O (IJS, 2015)

A Study of the Antimicrobial Effectiveness of Diluted Antiseptics in Nigeria. - AKINKUNMI, E. O.,; Akinyemi, O. A.,; Olasehinde, O. O. (British Journal of Pharmaceutical Research, 2015)

A STUDY OF THE ORGANIC RICHNESS AND PETROPHYSICAL CHARACTERISTICS OF SELECTED SHALES FROM THE ANALYSIS OF WIRELINE LOGS: A CASE OF “NEYA” FIELD, NIGER DELTA - D. E. Falebita; Ayeni,O. Z.; O. G. Bayowa; Anukwu, G. C. (Ife Journal of Science, 2015)

A Study of the Organic Richness and Petrophysical Characteristics of Selected Shales from the Analysis of Wireline logs: A Case of “Neya” Field, Niger Delta. - D. E. Falebita; Ayeni,O. Z.; O. G. Bayowa; Anukwu, G. C. (Ife Journal of Science, 2015)

Stylistic Analysis of Igbo’laja Terracotta Sculptures of Owo - Babasehinde A Ademuleya (Mediterranean Journal of Social Sciences, 2015)
This paper is an attempt at identifying the stylistic variables as evident in the treatment of forms and features of the Owo terracotta sculptures with a view to determining sameness and differences (of hands) in the production of the sculptures. The paper focussed mainly on the distinctive traits that are indeed peculiar to Owo and cannot be found even in the neighbouring art traditions (of Ife and Benin) using the “group theory”. Data were collected from primary and secondary sources with the study relying heavily on primary sources of data. Critical observation of the sculptures were made for proper formal analysis while heads and fragments of heads were purposively selected for a meaningful stylistic analysis, since the available heads and assembled head fragments do not merge appropriately with the headless bodies and other assembled fragments. Interviews were also conducted with the head of the local artists’ guild in Owo. The secondary sources provided information on previous studies on art traditions acclaimed as having noticeable stylistic similarities to the Owo terracotta sculptures (i.e. Ife and Benin). The paper posited that, despite the diversity of styles or sub-styles in the sculptures, they generally depict mood and movement, a trait found to be distinctive of Owo terracotta sculptures.

SUBSIDENCE PATTERNS IN THE NIGERIAN SECTOR OF BENIN (DAHOMEY) BASIN: EVIDENCE FROM THREE OFFSHORE WELLS. - Olabode, S.O. (Ife Journal of Science, 2015)

Surface DC Resistivity Survey of Contamination beneath Ido-Osun Dumpsite, Southwestern Nigeria - O. G. Bayowa; D. E. Falebita; Adegboyega, OR (Geofisica Internationacional, 2015)

Susceptibility of Methicillin Resistant Coagulase-Negative Staphylococci Isolated from Faecal Samples of Children to Commonly Used Antiseptic Agents. - AKINKUNMI, E. O.,; A. Lamikanra (African Journal of Infectious Diseases, 2015)

SYNTHESIS AND OPTICAL PROPERTIES OF SELF-ASSEMBLED COORDINATION POLYMER OF Zn(II) IONS WITH PHENYLMALONIC ACID AND 4-1H-AMINO- 1,2,4- TRIAZOLE - Mbonu, J. I. (Ife Journal of Science, 2015)

SYNTHESIS AND SPECTROSCOPIC STUDIES OF SCHIFF BASES FROM VARIOUSLY SUBSTITUTED BENZALDHYDES AND 2-AMINOMETHYL PYRIDINE - Shaibu, Rafiu O; Watkins, Gareth M (Ife Journal of Science, 2015)

THEORETICAL STUDY OF THE CHARACTERIZATION OF MIXED-LIGAND COMPLEXES OF Ni (II) DIMETHYLGLYOXIME - Adejoro, I. A.; Akintoye, B.; Adeboye, O. O.; Akinyele, O. F. (Ife Journal of Science, 2015)

THEORETICAL STUDY OF THE CHARACTERIZATION OF MIXED-LIGAND COMPLEXES OF Ni (II) DIMETHYLGLYOXIME - Adejoro A. I; Akintoye, B.; Adeboye O.O; Akinyele, O. F. (IJS, 2015)

TOTAL PETROLEUM HYDROCARBONS IN ORGANS OF COMMERCIALLY AVAILABLE FISH; TRACHURUS TRECAE (CADENAT, 1949) FROM OLIHA MARKET, BENIN CITY, NIGERIA - Enuneku, A. A .,; Ainerua M; Erhunmwunse, N. O .,; Osakue O. E (ife journal of science, 2015)

Transversing the Valley of Death: Understanding Determinants to Commercialisation of Research Outputs - I. O. Abereijo (African Journal of Economic and Management, 2015)

A TWO FISH SPECIES STUDY OF THE PARASITIC HELMINTH FAUNA OF Synodontis filamentosus (BOULENGER, 1901) AND Calamoichthys calabaricus (SMITH, 1865) FROM LEKKI LAGOON, LAGOS, NIGERIA - Akinsanya Bamidele (Ife Journal of Science, 2015)

Unemployment and Poverty as Sources and Consequence of Insecurity in Nigeria: The Boko Haram Insurgency Revisited - Usman, S. A. (African Journal of Political Science and International Relations, 2015)

The Use of Social Media in Real Estate Transactions in Lagos, Nigeria - T. B. Babatunde; Ajayi, C. A.; Oladokun, T.T. (6thcidb Postgraduate Conference hosted from 2-4 February 2016, 2015)

A Validated Method for Quantification of Efavirenz in Dried Blood Spots (DBS) using HPLC-MS/MS - Amara, Alieu B.; Else, Laura J.; Tjia, John; Adeniyi Olagunju; Puls, Rebekah L.; Khoo, Saye; Back, David J. (Therapeutic Drug Monitoring, 2015)
Background: Efavirenz (EFV) is one of the preferred components of first line antiretroviral treatment. EFV is characterised by a long plasma half-life (40-55h) with large inter-patient variability which raises the potential for individualisation of therapy. Analyses of EFV levels in plasma require specialised facilities (cold storage/transport) which, in resource-limited settings (RLS), can be problematic; DBS-EFV measurements thus provide a cheap, easy alternative for therapeutic drug monitoring. Our aim was to develop and validate a LC-MS/MS method to quantify EFV in DBS collected as part of clinical trials in RLS. Methods: DBS for standards, QC and patient samples, were excised and then extracted with ethyl acetate/n-hexane (50/50 v/v) after addition of internal standard (IS) hexobarbital, and 1mol/L K2CO3. The extract was evaporated to dryness, the residue reconstituted in mobile phase and analysed directly by LC-MS/MS. Gradient elution was on a reverse-phase C18 column using 1mmol/L ammonium acetate in water and acetonitrile. Quantification was by Selected Reaction Monitoring (SRM) in negative ionisation mode. DBS samples were obtained at several time-points over 24hr from HIV+ patients on either 400 or 600 mg EFV in combination with emtricitabine/tenofovir. Results: The IS and EFV eluted at 2.68 and 3.54 minutes respectively in a 5 minute run time. Matrix effects were minimal (-5.4%). Calibration curves were validated over a concentration range of 25-5000 ng/mL. Intra and inter assay variation ranged between 6.7-8.7% for imprecision and 100.3-104.2% for accuracy. Mean recovery was >64%. The DBS data showed a strong positive correlation with a validated plasma EFV assay (R=0.9764, P<0.001). EFV concentrations from DBS were approximately 42% lower than the paired plasma values and the ratio of blood/plasma did not change over the dosing interval. Conclusion: The validated assay is now routinely applied to clinical samples measuring DBS-EFV for PK analysis. The methodology is robust, accurate and sensitive.

A validated method for quantification of efavirenz in dried blood spots (DBS) using HPLC-MS/MS - Amara, A; L. Else; J Tjia; Olagunju, A; R. L. Puls; S Khoo; D. J. Back (Therapeutic Drug Monitoring, 2015)
BACKGROUND: Efavirenz (EFV) is one of the preferred components of first-line antiretroviral treatment. EFV is characterized by a long plasma half-life (40-55 hours) with large interpatient variability, which raises the potential for individualization of therapy. Analyses of EFV levels in plasma require specialized facilities (cold storage/transport) which, in resource-limited settings, can be problematic; dried blood spots (DBS)-EFV measurements thus provide a cheap easy alternative for therapeutic drug monitoring. Our aim was to develop and validate a liquid chromatography-mass spectrometry method to quantify EFV in DBS collected as part of clinical trials in resource-limited settings. METHODS: DBS for standards, quality control samples, and patient samples were excised and then extracted with ethyl acetate/n-hexane (50/50 vol/vol) after addition of internal standard hexobarbital, and 1 mol/L K2CO3. The extract was evaporated to dryness, the residue reconstituted in mobile phase and analyzed directly by liquid chromatography-mass spectrometry. Gradient elution was on a reverse-phase C18 column using 1 mmol/L ammonium acetate in water and acetonitrile. Quantification was by selected reaction monitoring in negative ionization mode. DBS samples were obtained at several time points over 24 hours from HIV+ patients on either 400 or 600 mg EFV in combination with emtricitabine/tenofovir. RESULTS: The internal standard and EFV eluted at 2.68 and 3.54 minutes, respectively in a 5-minute run time. Matrix effects were minimal (-5.4%). Calibration curves were validated over a concentration range of 25-5000 ng/mL. Intra-assay and interassay variations ranged between 6.7% and 8.7% for imprecision and 100.3% and 104.2% for accuracy. Mean recovery was >64%. The DBS data showed a strong positive correlation with a validated plasma EFV assay (R = 0.9764, P < 0.001). EFV concentrations from DBS were approximately 42% lower than the paired plasma values, and the ratio of blood/plasma did not change over the dosing interval. CONCLUSIONS: The validated assay is now routinely applied to clinical samples measuring DBS EFV for pharmacokinetic analysis. The methodology is robust, accurate, and sensitive.

Validation and clinical application of a method to quantify nevirapine in dried blood spots and dried breast milk spots - Adeniyi Olagunju; Amara, Alieu; Catriona Waitt; Laura Else; Sujan Penchala; Bolaji, Oluseye; Julius Soyinka; Marco Siccardi; David Back; Andrew Owen; Khoo, Saye (Journal of Antimicrobial Chemotherapy, 2015)
OBJECTIVES: The validation and clinical application of an LC-MS/MS method for the quantification of nevirapine in dried blood spots (DBS) and dried breast-milk spots (DBMS) are presented. METHODS: DBS and DBMS were prepared from 50 and 30 μL of nevirapine-spiked whole blood and human breast milk, respectively. Chromatographic separation was achieved on a reverse-phase C18 column with 0.1% formic acid in water/acetonitrile using a solvent gradient programme at a flow rate of 400 μL/min, and detection was by a TSQ Quantum Access triple quadrupole mass spectrometer. The clinical application was evaluated in HIV-positive nursing mothers and their breastfed infants. RESULTS: The assay was validated over the concentration range 50-10,000 ng/mL. Accuracy ranged from 93.3% to 113.4% and precision ranged from 1.9% to 12.0%. The mean (percentage coefficient of variation) recovery of nevirapine from DBS and DBMS was ≥ 70.7% (≤ 8.2) and the matrix effect was ≤ 1.04 (≤ 6.1). Nevirapine was stable in DBS and DBMS for ≥ 15 months at room temperature and -80°C. Mean (SD) AUC0-12, Cmax and Cmin in maternal plasma versus breast milk were 57,808 ng · h/mL (24,315) versus 55,817 ng · h/mL (22,368), 6140 ng/mL (2605) versus 5231 ng/mL (2215) and 4334 ng/mL (1880) versus 4342 ng/mL (2245), respectively. The milk-to-plasma concentration ratio over the dosing interval was 0.94 (0.15). Infant plasma concentrations 2 and 8 h after maternal dosing were 580.6 ng/mL (464.7-1607) and 584.1 ng/mL (381.5-1570), respectively. CONCLUSIONS: These methods further extend opportunities for conducting clinical pharmacokinetic studies in nursing mother-infant pairs, especially in resource-limited settings.

Validation and clinical application of a method to quantify nevirapine in dried blood spots and dried breast-milk spots - Adeniyi Olagunju; Amara, Alieu; Catriona Waitt; Laura Else; Sujan D. Penchala; Bolaji, Oluseye; Julius Soyinka; Marco Siccardi; David Back; Andrew Owen; Khoo, Saye (Journal of Antimicrobial Chemotherapy, 2015)
Objectives The validation and clinical application of an LC–MS/MS method for the quantification of nevirapine in dried blood spots (DBS) and dried breast-milk spots (DBMS) are presented. Methods DBS and DBMS were prepared from 50 and 30 μL of nevirapine-spiked whole blood and human breast milk, respectively. Chromatographic separation was achieved on a reverse-phase C18 column with 0.1% formic acid in water/acetonitrile using a solvent gradient programme at a flow rate of 400 μL/min, and detection was by a TSQ Quantum Access triple quadrupole mass spectrometer. The clinical application was evaluated in HIV-positive nursing mothers and their breastfed infants. Results The assay was validated over the concentration range 50–10 000 ng/mL. Accuracy ranged from 93.3% to 113.4% and precision ranged from 1.9% to 12.0%. The mean (percentage coefficient of variation) recovery of nevirapine from DBS and DBMS was ≥70.7% (≤8.2) and the matrix effect was ≤1.04 (≤6.1). Nevirapine was stable in DBS and DBMS for ≥15 months at room temperature and −80°C. Mean (SD) AUC0–12, Cmax and Cmin in maternal plasma versus breast milk were 57 808 ng·h/mL (24 315) versus 55 817 ng·h/mL (22 368), 6140 ng/mL (2605) versus 5231 ng/mL (2215) and 4334 ng/mL (1880) versus 4342 ng/mL (2245), respectively. The milk-to-plasma concentration ratio over the dosing interval was 0.94 (0.15). Infant plasma concentrations 2 and 8 h after maternal dosing were 580.6 ng/mL (464.7–1607) and 584.1 ng/mL (381.5–1570), respectively. Conclusions These methods further extend opportunities for conducting clinical pharmacokinetic studies in nursing mother–infant pairs, especially in resource-limited settings.

When There Are Atmospheric Data Gaps: What Can Researchers Do? - A. Ayanlade (In Gbadegesin, A. S., Eze E. B., Oluwagbenga O. O. I., & Fashae O. A. (2015). Frontiers in Environmental Research and Sustainable Environment in the 21st Century, 2015)
This study aims at describing and evaluating the relevance of Geographical Information System (GIS) procedures as a standard technique to model atmospheric parameters when there are several data gaps. Generally, high resolution atmospheric parameters are needed to assess the impacts of climate change on crop productivity at the local level, using data at the level of individual farm units. Such high resolution climatic data are non-existent in the West African setting because of the extremely sparse meteorological station network. The problems often arise as to what values to attach to climatic variables at points other than these nodes where there are data gaps. Therefore, GIS interpolation and downscaling methods were used to assess how gaps in climatic parameters could be filled using Nigeria as a case study. Several GIS interpolation methods have been tested for the production of maps in this study. After many attempts of the qualitative and quantitative validations, the last of these- Ordinary Kriging- was chosen for the map productions. A major strength of the method is that measured spatial dependence in the weather parameter of interest and this is used to produce digital maps. Ordinary Kriging was used to interpolate the point observations from a network of rainfall base stations. The results from this study show that GIS interpolation are helpful for downscaling spatial dynamics of climate and also useful in forecasting probable period for farming activities.

Why should I take drugs for your infection?" Outcomes of formative research on the use of HIV pre-exposure prophylaxis in Nigeria - Idoko, J; Folayan, MO; Dadem, NY; Kolawole, GK; Anenih, J; Alhassan, E (BMC Public Health, 2015)

ZINC (II) METAL ION COMPLEXES OF CHITOSAN: TOWARD HETEROGENEOUS-ACTIVE CATALYSTS FOR THE POLYMERIZATION OF VINYL ACETATE - Adewuyi, S.; Bisiriyu, I. O.; Akinremi, C. A. (IJS, 2015)

“Covering the Proverbial Distance Faster and Safer” a review of Aderemi Raji-Oyelade’s Playful Blasphemies, Postproverbials as Archetypes of Modernity in Yorùbá Culture" - Ayoh'OMIDIRE, Félix (Matatu: Journal for African Culture and Society, 2015)

“Favelas, Fome Zero and State Welfarism or the Quest for Racial Equality and Empowerment in Contemporary Brazil” - Ayoh'OMIDIRE, Félix (EUREKA: A Journal of Humanistic Studies, 2015)

“Mestre Didi: Nago Tales and the Re-Invention of Literary Genres in Afro-Brazilian Literature” - Ayoh'OMIDIRE, Félix (Ibadan Journal of European Studies, 2015)

“Service Quality in Management of Office property in Lagos metropolis, Nigeria”. - Adenusi, R.D.,; Odunfa, V.O.,; Oladokun, T.T.,; J.T., Gbadegesin (Responsive Built Environment,, 2015)

Corrosion Investigation In Reinforced Concrete Using a Potentiostat - Olorunniwo, O.E.; Popoola, A.P.I.; Aremo, B.; Ige, O.O. (African Corrosion Journal, 2015)
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Diarrhoeagenic Escherichia coli in mother-child Pairs in Ile-Ife, South Western Nigeria - Odetoyin, Babatunde W; Hofmann, Jennifer; Aboderin, Aaron O; Okeke, Iruka N (BMC infectious diseases, 2015)
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A Model for Animation of Yorùbá Folktale Narratives - {Stephen Adéyemí Fọlárànmí (African Journal of Computing & ICT, 2015)
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Prevalence and factors associated with depressive symptoms among Yoruba adults in a semi-urban community in South-Western Nigeria - Akinsulore, Adesanmi; Olapeju A. Esimai; Afolabi, Olusegun Tope; Aloba, Olutayo Olubunmi; Mapayi, Boladale Moyosore (Journal of Behavioral Health, 2015)
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Prevalence of Soil Transmitted Helminthes among School Children in Central Local Government Area Ile-Ife Osun State. Nigeria - Olaniran, O; Ajayi, OO; Odetoyin, BW; Afolayan, DO; Awoyeni, EA; Adekunle, OT; Oyetoke, OO (International Journal of Novel Research in Interdisciplinary Studies, 2015)
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Production and Characterization of Clay Bonded Carbon Refractory from Ifon Clay and Spent Graphite Electrode - Ranti, Oke Samuel; Kayode, Talabi Henry; Olorunniwo, Olusegun Emmanuel; Atanda, Pethuel Olayide; Aramide, Fatai Olufemi (International Journal of Metallurgical Engineering, 2015)
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The Role of Methicillin-Resistant Staphylococcus aureus in Clinical infections in Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, South Western Nigeria - Onelum, Obianuju; Odetoyin, Babatunde; Onipede, Anthony; Oyelese, Adesola (J Microbiol Exp, 2015)
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Sexual orientation and quality of life among students of Obafemi Awolowo University (OAU), Nigeria. - Boladale, Mapayi; Olakunle, Oginni; Olutayo, Aloba; Adesanmi, Akinsulore (African health sciences, 2015)
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The Thermal Analysis of Fuel Fired Crucible Furnace Using Autodesk Inventor Simulation Software - Abioye, A.A.; Atanda, P.O.; Kolawole, OF; Olorunniwo, O.E.; Adetunji, A.R.; Abioye, OP; Akinluwade, K.J. (Advances in Research, 2015)
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Translation, cross-cultural adaptation and psychometric evaluation of yoruba version of the short-form 36 health survey - Chidozie Emmanuel Mbada; Adeogun, Gafar Atanda; Ogunlana, Michael Opeoluwa; Rufus Adesoji Adedoyin; Akinsulore, Adesanmi; Taofeek Oluwole Awotidebe; Idowu, Opeyemi Ayodiipo; Olaoye, Olumide Ayoola (Health and quality of life outcomes, 2015)
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The Yoruba version of the Beck Hopelessness Scale: psychometric characteristics and correlates of hopelessness in a sample of Nigerian psychiatric outpatients - Aloba, Olutayo; Akinsulore, Adesanmi; Mapayi, Boladale; Oloniniyi, Ibiduniyi; Mosaku, Kolawole; Alimi, Taiwo; Esan, Olufemi (Comprehensive psychiatry, 2015)
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{Changing the face of the built environment through murals: The Ile-Ife example} - Folárànmí, Stephen; Oyèníyì Oyèwolé (Responsive Built Environment, Issues, Strategies and Policies in the Developing World., 2015)
Art is known to be an agent of value and aesthetic in the built environment wherever such forms of art are employed, especially in societies where they are appreciated and enjoyed. Murals as a form of public art particularly have taken up a form by creating a symbiotic relationship with the spaces and walls within cities, towns and private homes. The lack of appreciation of this art form in the Nigerian environment and its non-inclusiveness in the past has devoid this art of its value. The paper discusses the recent murals in Ile-Ife especially on the walls of Obáfémi Awólówò University campus with a view to determining their social and environmental relevance in the built up spaces. It adopts structured interview to collect data from users of public spaces. The study population comprised of students, staff and other public space users in the study area. A descriptive approach was used in analyzing the murals based on form and subject matter as it relates to the public space. Findings revealed that public space users are receptive to the new murals and view them as a positive development. Results also showed that more spaces should be made available for use of posters as well as for art. The study concluded that the recent murals have added more value and aesthetic appeal to the spaces in which they are painted, thereby receiving positive responses from users of public spaces. It suggested that a policy should be enacted to incorporate creation of art as part of the budget in the design and construction of public spaces.
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Keywords: Murals; Public Art.; Public Space and Built Environment

{The Stained-Glass of Selected Churches in Ibadan} - Folárànmí, Stephen; Imafidor, Jonathan (Responsive Built Environment, Issues, Strategies and Policies in the Developing World., 2015)
Art has always been and is still being used as a veritable tool in the hands of artists in promoting the Christian religion. Sculptures, mosaics, murals and stained-glass are some of the artistic media used to augment the aesthetic appeal of church architecture and most importantly earn the Christian faithful better concentration. However, the quest for larger spaces to accommodate the growing population of Christian converts and recent development in the built environment led to the demolition/renovation of existing structures and as a result churches give little or no room for the survival of some artworks. Artworks such as murals and stained-glass which are directly executed or fitted permanently on walls are usually affected as a result of these developments. This paper identified and analyzed the existing stained-glass in selected churches in Ibadan with a view to establishing their functions and relevance in the public spaces. The study adopted art historical methodology by using direct observatory and descriptive analysis. Interviews were conducted with key informants in the study area. Findings revealed that most churches with stained-glasses in the study area are old churches belonging to the Catholic, Methodist and Anglican denominations, and that many new churches no longer incorporate stained-glass in their churches, thereby depriving the built environment of this artistic form. It recommends that some of these churches be designated as tourist sites and be preserved for the good of the built environment as it is practiced in developed nations of the world.
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Keywords: Christianity; church; communication; public spaces; stained-glass.

Electronic Structure of Fe3Si on Si(100) Substrates - C. Lal; G. DiSanto; M. Caputo; M. Panighel; B.A. Taleatu; A. Goldoni; I.P. Jain (AIP Proceedings, 2014)

Pharmacogenetics of efavirenz excretion into human breast milk and transfer to breastfed infants [Abstract #888] - Adeniyi Olagunju; Marco Siccardi; Okafor, Ogechi; Bolaji, Oluseye; Khoo, Saye; Andrew Owen (21st Conference on Retroviruses and Opportunistic Infections (CROI), 2014)
Background: The influence of drug metabolizing enzyme, transporter and nuclear receptor single nucleotide polymorphisms (SNPs) on efavirenz (EFV) concentrations in human breast milk and infants exposed through breast milk is understudied. SNPs in maternal CYP2B6, NR1I3, ABCG2 and ABCB5 were investigated here. Methods: HIV positive nursing mothers (n = 51) receiving once daily regimens containing 600 mg EFV and their exclusively breastfed infants were recruited from 3 Nigerian hospitals. Paired dried blood spots (DBS; maternal and infant) and dried breast milk spots (DMS) were collected 12 - 14 hours post maternal dose. EFV was quantified by validated LC-MS/MS. Plasma EFV concentration was estimated using [DBS[EFV]/(1-HCT)]*fbpp, where HCT is average haematocrit and fbpp is fraction bound to plasma protein. Genotyping for CYP2B6 rs3745274, NR1I3 rs2307424, NR1I3 rs3003596, ABCB5 rs6461515, ABCB5 rs2301641, ABCG2 rs2231164 and ABCG2 rs2622604 was conducted. Associations of EFV concentrations with SNPs and demographic factors were investigated by univariate (Mann-Whitney U test) and multivariate analyses (multiple linear regression). P < 0.05 was considered statistically significant. Results: Median (IQR) EFV breast milk concentration was 2280 (1180, 3270) ng/ml. Using 150ml/kg/day as average milk intake, this equates to ~340 (177, 491) ug/kg/day infant dose and resulted in 178 (87.7, 340) ng/ml in infant plasma. Maternal plasma EFV was 2310 (1580, 4460) ng/ml and median (IQR) milk-to-maternal plasma ratio was 0.82 (0.51, 1.1). There were significant correlations between maternal plasma and breast milk EFV concentrations (p = 1.3 x 10-12; rho = 0.80) and between breast milk and infant plasma (p = 7.9 x 10-5; rho = 0.52). Significant differences in maternal, infant and breast milk EFV concentrations were observed based on CYP2B6 rs3745274 genotypes (Figure 1). Only CYP2B6 rs3745274 was independently associated with breast milk [B = 0.22 (0.10, 0.35), p = 0.001], maternal [B = 0.23 (95% CI: 0.13, 0.32), p=1.5 x 10-5] and infant [B = 0.23 (0.09, 0.37), p = 0.002] EFV concentrations in multivariate analyses. Other statistically significant SNP associations were observed in univariate but not multivariate analysis. Conclusion: CYP2B6 rs3745274 was independently associated with EFV concentrations in human breast milk and infants exposed through breast milk. Further study is warranted to define clinical significance and implications for stratified medicine in these patients.

Relative genetic contribution to the pharmacokinetics of commonly prescribed antiretrovirals (Abstract #504) - Marco Siccardi; Adeniyi Olagunju; Marco Simiele; Antonio D’Avolio; Andrea Calcagno; Giovanni Di Perri; Stefano Bonora; Andrew Owen (21st Conference on Retroviruses and Opportunistic Infections (CROI), 2014)
Background: Antiretroviral pharmacokinetics is characterised by broad variability influenced by numerous factors affecting absorption, distribution, metabolism and elimination. Recently, a relative genetic contribution (rGC) of 0.904 (0.64 – 0.97) was reported for nevirapine (NVP) AUC0-6h (Micheli et al, Pharmacogenet Genomics, 2013). The aim of this study was to assess the Cmin rGC for a panel of antiretroviral drugs to rank agents according to the degree to which heritability influences their pharmacokinetics. Methods: Patients from the Therapeutic Drug Monitoring Registries of the University of Turin and the University of Liverpool were included in the study. Inclusion criteria for both cohorts were as follows: receiving boosted lopinavir (LPV/r, 300/100 mg twice daily), boosted atazanavir (ATV/r 300/100 mg once daily), unboosted ATV (ATV, 400mg once daily), efavirenz (EFV, 600 mg once daily), NVP (400 mg once daily) or raltegravir (RAL, 400 mg twice daily), age>18 years, not receiving drugs known to contribute to drug-drug interactions. Plasma drug concentrations were determined using validated HPLC or LC-MS/MS methods. Intrapatient (SDw) and interpatient (SDb) variability were measured in patients with plasma concentrations available from more than one occasion. The rGC was calculated using the following equation: 1-(1/F) where F= SDb2/SDw. Statistical significance for genetic contribution was calculated using F-test, α = 0.05. Results: A total of 211 patients were included in the study, 37 receiving LPV/r, 24 receiving ATV/r, 24 receiving ATV, 82 receiving EFV, 20 receiving NVP and 24 receiving RAL. SDw and SDb were 38% and 43% for LPV/r (n = 37), 49% and 50% for ATV/r (n = 24), 54% and 104% for ATV (n = 24), 33% and 60% for EFV (n = 82), 19% and 44% for NVP (n = 20), and 81% and 95% for RAL (n = 24), respectively. Mean with 95% CI rGC was calculated to be 0.35 (0.06-0.55) for LPV/r, 0.15 (0-0.6) for ATV/r, 0.55 (0.35 – 0.7) for ATV, 0.78 (0.68 – 0.85) for EFV, 0.82 (0.62-0.91) for NVP and 0.08 (0-0.56) for RAL (Figure). Genetic contribution was statistically significant (p<0.05) for ATV, EFV and NVP. Discussion: The rank order for genetic contribution to variability in Cmin for the study drugs was NVP > EFV > ATV > LPV/r > ATV/r > RAL indicating class specific differences exist. Interestingly, these data indicate that ritonavir reduces the genetic contribution to variability in ATV Cmin presumably through inhibition of gene products such as CYP3A4 and ABCB1. Drugs with higher rGC scores may represent better candidates for pharmacogenetic studies.

Utility of the HRN™ (hepatic cytochrome P450 reductase null) mice for investigating mechanisms of liver toxicity of carboxylic-acid-containing drugs - Akingbasote, James; Foster, Alison; Sarda, Sunil; Jones, Huw; Wilson, Ian; Kenna, Gerry (Abstracts of the 50th Congress of the European Societies of Toxicology (EUROTOX), 2014)
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FOOD SECURITY AND ORAL HEALTH OF UNIVERSITY STUDENTS IN NIGERIA. - Ogunbodede, Eyitope; AMEDARI, M.I.; Rudolph, Michael (2014)
Objective: Oral health is associated with the availability, accessibility, and utilization of food. The objective of this study is to investigate the physical and economic access to sufficient, safe and nutritious food among university students in Nigeria, and relate these to their oral health.Method: Extensive literature review was conducted using internet sources, journal publications and official reports. Cross-sectional stratified random sampling was conducted for undergraduate university students resident on campus at Obafemi Awolowo University. Data was collected using a modified format of the United States Household Food Security Survey Module of the USDA, with a section on oral health. Data was analysed using the SPSS Statistical package (Version 16) and differences were taken as significant at p<0.05. Result: Using the data collected, respondents were categorised into a “food secure” and “food insecure” groups. Food insecure individuals were more likely to have dental pathologies including toothache, gum bleeding, and oro-facial pain. They also had more frequent history of tooth removal, irregular dental visit and less frequent tooth brush Conclusion: Individuals challenged by the unavailability, inaccessibility, and poor utilization of safe and nutritious foods tend to have poorer oral health compared to those with better food security.
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Undergraduate Geriatric Dentistry Programs in Spain - San-Martin, Laura; CASTAO SEIQUER SR, A; Ribas Pérez, David; Ogunbodede, Eyitope (Current Research in Dentistry, 2014)
Objective: Over the past few decades, the world has experienced a gradual increase in the percentage of elderly people aged 65 years and over. As this elderly population increases, evidence suggests that their demand for dental services would increase. The increasing population of the elderly population in Spain has underlined the need for the dental profession to take pay particular attention to the oral health needs of older patients. The aim of this report is to present a preliminary assessment of the undergraduate Geriatric Dentistry programs in Spanish dental schools.Method: Study participants included all the dental schools in Spain (n=19). Using a simple, 12-item questionnaire, information was collected regarding the geriatric dental education programs from the official websites of all the schools. Results: Only 42% (n=8) of schools offered a specific geriatric dentistry course. No significant differences were found in the proportion of public and private dental schools with geriatric dentistry departments (p=0.1312). Conclusion: More studies on the curriculum content, design, implementation and evaluation of geriatric dentistry programs at the undergraduate level should be developed. Research must also focus on assessing the access and improvement to the oral care of the elderly population. Dental schools, organizations, local and state governments need to work together, using a multidisciplinary approach, in responding to the unmet needs of the elderly population.
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Undergraduate Geriatric Dentistry Programs in Spain - San-Martin, Laura; CASTAO SEIQUER SR, A; Ribas Pérez, David; Ogunbodede, Eyitope (Current Research in Dentistry, 2014)
Objective: Over the past few decades, the world has experienced a gradual increase in the percentage of elderly people aged 65 years and over. As this elderly population increases, evidence suggests that their demand for dental services would increase. The increasing population of the elderly population in Spain has underlined the need for the dental profession to take pay particular attention to the oral health needs of older patients. The aim of this report is to present a preliminary assessment of the undergraduate Geriatric Dentistry programs in Spanish dental schools.Method: Study participants included all the dental schools in Spain (n=19). Using a simple, 12-item questionnaire, information was collected regarding the geriatric dental education programs from the official websites of all the schools. Results: Only 42% (n=8) of schools offered a specific geriatric dentistry course. No significant differences were found in the proportion of public and private dental schools with geriatric dentistry departments (p=0.1312). Conclusion: More studies on the curriculum content, design, implementation and evaluation of geriatric dentistry programs at the undergraduate level should be developed. Research must also focus on assessing the access and improvement to the oral care of the elderly population. Dental schools, organizations, local and state governments need to work together, using a multidisciplinary approach, in responding to the unmet needs of the elderly population.
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Inequality in oral health between rural and urban areas - Ogunbodede, Eyitope (2014)
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Effect of Methods of Application of Compost and Inorganic N on Carbon Dioxide Evolution, N and P Mineralization. - Atoloye, Idowu A.; A. S. Ekundayo R. A., Erhunmwunse; A. Olayinka (2014)
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Integration of Oral Health into Primary Health Care System: Views of Primary Health Care Workers in Lagos State, Nigeria - Braimoh, Matilda; Ogunbodede, Eyitope; Adeniyi, Abiola (journal of public health in africa, 2014)
The limited access to oral health care in developing countries can be greatly improved by integrating oral health into the Primary Health Care (PHC) system. This study was designed to assess the views of PHC workers on integrating oral health care into the PHC system. A self-administered questionnaire sur- vey was conducted in two selected local govern- ment areas of Lagos State. The instrument contained three sections assessing socio- demographic features, knowledge of common oral diseases and views on integration of oral health into PHC respectively. The mean knowl- edge score was 7.75 (SD=±1.81), while 60.4% of the respondents had average knowledge scores. Educational status (P=0.018) and des- ignation (P=0.033) were significantly related to the mean knowledge scores. There was no significant difference in the oral health knowl- edge of the various cadres (P=0.393). Majority (85.4%) of the respondents were willing to include oral health education in their job schedule and 82% believed they needed more training on oral health. The knowledge of the respondents on the causes of the common oral diseases was deficient. Oral health education should be included in the future curriculum of these personnel.
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A Spatial Conceptual Public Health Data Model for Nigeria - Adebayo Peter Idowu, Rotimi Emnanuel Adagunodo & Kehinde Oladipo Williams (International Journal of Research in Business and Technology, 2014)

“Quilombismo e o tropo de Exu na poesia de Abdias do Nascimento” - Ayoh'OMIDIRE, Félix; Verene Doll; Anne Begenat-Neuschäfer (Poesia do tereiro espaço: Lírica lusófona contemporânea, 2014)

) Effects of Characteristics of Nigerian Students on Perceived Satisfaction of Academic Facilities in Private Universities in Ogun State, Nigeria - Oluwunmi, A.O.; Ajayi, C. A. (African Research Review, 2014)

. (). Pre-shelling parameters and conditions that influence the whole kernel out-turn of steam-boiled cashew nuts - Ogunsina, B.S; A.I. Bamgboye (Journal of the Saudi Society of Agricultural Sciences, 2014)

ABSORBANCE AND FLUORESCENCE STUDIES ON PORPHYRIN NANOSTRUCTURES (PNR) AS LIGHT HARVESTERS IN DYE SENSITIZED SOLAR CELLS (2014)

The Abuja +12 declaration: implications for the HIV response in Africa. - Mburu, R; Folayan, MO; Akanni, O (African Journal of Reproductive Health, 2014)

ACRYLAMIDE RESULTING FROM HEAT-TIME TREATMENT IN CAJANUS CAJAN, A NEGLECTED AND UNDERUTILIZED LEGUME. - Dankwah, R.; Awuni, M.; Ofosu, I. W. (Ife Journal of Science, 2014)

Addressing Ebola-related stigma: lessons learned from HIV/AIDS. - Davtyan, M; Brown, B; Folayan, M (Glob Health Action, 2014)

Addressing the socio-development needs of adolescents living with HIV/AIDS in Nigeria: a call for action - Folayan, MO; Harrison, A; Odetoyinbo, M; Brandon, B (African Journal of Reproductive Health, 2014)

ADSORPTION CHARACTERISTICS AND MECHANISMS OF PLANTAIN PEEL CHARCOAL IN REMOVAL OF CU (II) AND ZN (II) IONS FROM WASTEWATERS - Umukoro, E. H.; J.A.O. Oyekunle; O. Owoyomi; A.O. Ogunfowokan; I.A. Oke (Ife Journal of Science, 2014)

Antibiotic Resistance and Public Health Perspective of Bacterial Contamination of Nigerian Currency - Oluduro, A. O.; Omoboye, O. O.; Orabiyi, R. A.; Bakare, M. K.; David, O. M. (Advances in Life Science and Technology, 2014)

Apparent Digestibility Coefficient of Differently Processed Lima Bean (Phaseolus lunatus L.) for Clarias gariepinus Juveniles - "A. E. Falaye"; "A. Omoike"; "O. Orisasona" (Journal of Fisheries and Aquatic Science, 2014)

Appraisal of the national response to caries epidemic in children in Nigeria - Folayan, MO; Chukumah, NM; Onyejeka, N; Adeniyi, A; Olatosi, O (BMC Oral Health, 2014)

AN ASSESSMENT OF BIOCHEMICAL, PHYTOCHEMICAL AND ANTI- NUTRITIONAL COMPOSITIONS OF A TROPICAL FERN: Nephrolepis cordifolia L. (2014)

Association between knowledge of caries preventive practices, preventive oral health habits of parents and children and caries experience in children resident in a sub-urban Nigeria - Folayan, MO; Kolawole, KA; Oyedele, T; Chukumah, NM; Onyejaka, N; Agbaje, H; Oziegbe, EO; Oshomoji, OV (BMC Oral Health, 2014)

Beyond informed consent: other ethical consideration in the design and implementation of sexual and reproductive health research among adolescents in Nigeria - Folayan, MO; Haire, B; Harrison, A; Fatusi, O; Brown, B (African Journal of Reproductive Health, 2014)

THE BIOSORPTION OF CADMIUM AND LEAD IONS FROM AQUEOUS SOLUTION USING MUSA PARADISIACA STALK (2014)

Black market blood transfusions for Ebola: potential for increases in other infections - Folayan, MO; Brandon, B; Yakubu, A (Glob Health Action, 2014)

A Casual Model of Determinant of Students’ Attitude Towards Social Studies in Junior Secondary Schools in Osun State - Adeyemi B. A.; Ijiwole A.A. (The Journal of International Social Research, 2014)

A Causal Model of Determinant of Students’ Attitude towards Social Studies in Junior Secondary Schools in Osun State. - Adeyemi, B. A.; Ijiwole, A. A. (The Journal of International Social Research, 2014)

Challenges of Facility Management (FM) in the Manufacturing Industries in Nigeria - Oladokun, T.T. (Journal of International Real Estate and construction Studies, 2014)

Changes in sexual risk behavior among adolescents: is the HIV prevention programme in Nigeria yielding results? - Aboki, H; Folayan, MO; Daniel, U; Ogunlayi, M (African Journal of Reproductive Health, 2014)

Changes in the prevalence of dental caries among primary school children in Lagos State, Nigeria - Sofola, OO; Folayan, MO; Oginni, AB (Nigeria Journal of Clinical Practice, 2014)

COMPARATIVE ANALYSIS OF THE PHYTOCHEMICAL, PROXIMATE AND ELEMENTAL COMPOSITION OF CALOTROPIS PROCERA (Ait.F.) Ait.F. LATEX AND MORINGA OLEIFERA (LAM) SEED POWDER (2014)

COMPARATIVE PROPERTIES OF PURE AND SULPHONATED DYES EXTRACTED FROM HENNA (Lawsonia inermis (Linnaeus) AND KOLANUT (Cola nitida (Vert.) Schott & Endl.) PLANTS (2014)

Compassionate use of experimental interventions in the Ebola outbreak - Folayan, M; Brown, B; Yakubu, A; Peterson, K; Haire, B (Lancet, 2014)

Computer-Assisted-Audit Tools and Techniques and Financial Statement Fraud: Lessons from the Nigerian Banking Crises - Ayoola, T.J (International Conference on Accounting, Finance and Management on Accountability and Sustainable Business Development in Emerging Economies, 2014)

Considerations in design, implementation and reporting of research involving adolescents living with HIV in Nigeria: experience from the field - Folayan, MO; Odetoyinbo, M; Brown, B; Harrison, A (Nigerian Journal of Health Sciences, 2014)

CONSTRAINT MAP FOR LANDFILL SITE SELECTION IN AKURE METROPOLIS, SOUTHWESTERN NIGERIA. - Ojo, J. S.; M. O. Olorunfemi; Bayode, S.; Akintorinwa, O.J.; Omosuyi, G.O.; Akinluyi, F.O. (Ife Journal of Science, 2014)

CORRELATION OF METEOROLOGICAL PARAMETERS AND DUST PARTICLES USING SCATTER PLOT IN A RURAL COMMUNITY (2014)

Corruption and Insecurity: Threats to the Nigerian Youths - Agbalajobi, Damilola T (Ife Social Sciences Review, 2014)

Critical Factors Determining Rental Value of Residential Property in Ibadan Metropolis, Nigeria - Adegoke, O.J. (Journal of Property Management, 2014)

CYP2B6 516G>T (rs3745274) and smoking status are associated with efavirenz plasma concentration in a Serbian cohort of HIV patients - Adeniyi Olagunju; Marco Siccardi; Amara, Alieu; Jevtovic, Djordje; Kusic, Jovana; Andrew Owen; Dragovic, Gordana (Therapeutic Drug Monitoring, 2014)
Background: Genetic factors have been associated with efavirenz (EFV) plasma concentrations in different populations. In this study, we investigated the effects of CYP2B6 516G>T (rs3745274), CYP2B6 c.485-18C>T (rs4803419), CAR c.540C>T (rs2307424), CAR c.152-1089T>C (rs3003596) and smoking status in a cohort of Serbian HIV patients. Methods: HIV-positive patients, all Cacausian, were recruited from the HIV/AIDS Center at the Infectious and Tropical Diseases Hospital, University of Belgrade Teaching Hospital, Belgrade, Serbia. Mid-dose (10-14 hours post dose) EFV plasma concentration was determined using a validated liquid chromatography/tandem mass spectrometry method. Genotyping for CYP2B6 516G>T (rs3745274), CYP2B6 c.485-18C>T (rs4803419), CAR c.540C>T (rs2307424) and CAR c.152-1089T>C (rs3003596) was conducted using allelic discrimination real-time PCR assay. One-way analysis of variance (ANOVA), Mann-Whitney test, Pearson or Spearman correlation and multiple linear regression were used for data analysis. Results: Minor allele frequencies (MAF) were similar to frequencies reported in other European populations. The overall mean (95% CI) plasma EFV concentration was 2800 ng/ml (2460, 3140). Significant differences between patients based on CYP2B6 516G>T (rs3745274) genotypes were observed: GG (n = 60), 2320 ng/ml (2160, 2480); GT (n = 30), 3230 ng/ml (2790, 3670); and TT (n = 2), 10700 ng/ml (range: 6170, 15300) (p = 2.0 X 10-17). In multivariate linear regression analysis, CYP2B6 516G>T (rs3745274) ([beta] = 1770 ng/ml (1230, 2310), p < 0.0001) and smoking status ([beta] = -464 ng/ml (-1250, -43.3), p = 0.038) were independently associated with plasma EFV concentrations. Conclusions: The effects of CYP2B6 516G>T (rs3745274) and smoking status on EFV plasma concentration in the Serbian population have been established for the first time.

CYP2B6 516G>T (rs3745274) and smoking status are associated with efavirenz plasma concentration in a Serbian cohort of HIV patients - Olagunju, A; M Siccardi; Amara, A; D. Jevtovic; J. Kusic; Owen, A; G. Dragovic (Therapeutic Drug Monitoring, 2014)
BACKGROUND: Genetic factors have been associated with efavirenz (EFV) plasma concentrations in different populations. In this study, we investigated the effects of CYP2B6 516G>T (rs3745274), CYP2B6 c.485-18C>T (rs4803419), CAR c.540C>T (rs2307424), CAR c.152-1089T>C (rs3003596), and smoking status in a cohort of Serbian patients with HIV. METHODS: Patients with HIV positive, all whites, were recruited from the HIV/AIDS Center at the Infectious and Tropical Diseases Hospital, University of Belgrade Teaching Hospital, Belgrade, Serbia. Mid dose (10-14 hours after dose) EFV plasma concentration was determined using a validated liquid chromatography/tandem mass spectrometry method. Genotyping for CYP2B6 516G>T (rs3745274), CYP2B6 c.485-18C>T (rs4803419), CAR c.540C>T (rs2307424), and CAR c.152-1089T>C (rs3003596) was conducted using allelic discrimination real-time polymerase chain reaction assay. One-way analysis of variance, Mann-Whitney test, Pearson or Spearman correlation, and multiple linear regression were used for data analysis. RESULTS: Minor allele frequencies were similar to frequencies reported in other European populations. The overall mean (95% confidence interval) plasma EFV concentration was 2800 ng/mL (2460-3140). Significant differences between patients based on CYP2B6 516G>T (rs3745274) genotypes were observed: GG (n = 60), 2320 (range, 2160-2480) ng/mL; GT (n = 30), 3230 (range, 2790-3670) ng/mL; and TT (n = 2), 10,700 (range, 6170-15,300) ng/mL (P = 2.0 × 10). In multivariate linear regression analysis, CYP2B6 516G>T (rs3745274) [β = 1770 (1230 to 2310) ng/mL, P < 0.0001] and smoking status [β = -464 (-1250 to -43.3) ng/mL, P = 0.038] were independently associated with plasma EFV concentrations. CONCLUSIONS: The effects of CYP2B6 516G>T (rs3745274) and smoking status on EFV plasma concentration in the Serbian population have been established for the first time.

CYP3A4*22 (c.522-191 C>T; rs35599367) is associated with lopinavir pharmacokinetics in HIV-positive adults - Olagunju, A; Schipani, A; M Siccardi; Egan, D; S Khoo; D Back; Owen, A (Pharmacogenetics and Genomics, 2014)
The CYP3A4*22 (c.522-191 C>T; rs35599367) single nucleotide polymorphism has been associated with lower CYP3A4 mRNA expression and activity. We investigated the association of CYP3A4*22 with the pharmacokinetics of lopinavir through a population pharmacokinetic approach. The minor allele frequency for CYP3A4*22 was 0.035, and seven of 375 patients had a combination of CYP3A4*22 and SLCO1B1 521T>C alleles. Lack of information on the ethnicity in this cohort should be considered as a limitation. However, in the final model, the population clearance was 5.9 l/h and patients with CYP3A4*22/*22 had 53% (P=0.023) lower clearance compared with noncarriers. In addition, the combined effect of CYP3A4*22 with SLCO1B1 521T>C (previously shown to be associated with lopinavir plasma concentration) was analysed. We observed a 2.3-fold higher lopinavir trough concentration (Ctrough) in individuals with CYP3A4*22/*22, a 1.8-fold higher Ctrough with SLCO1B1 521CC and a 9.7-fold higher Ctrough in individuals homozygous for both single nucleotide polymorphisms, compared with noncarriers. A simulated dose-reduction scenario showed that 200/100 mg lopinavir/ritonavir was adequate to achieve therapeutic concentration in individuals with CYP3A4*22/*22 alone or in combination with SLCO1B1 521CC. These data further our understanding of the genetic basis for variability in the pharmacokinetics of lopinavir.

CYP3A4*22 (c.522-191 C>T; rs35599367) is associated with lopinavir pharmacokinetics in HIV-positive adults - Adeniyi Olagunju; Alessandro Schipani; Marco Siccardi; Deidre Egan; Khoo, Saye; David Back; Andrew Owen (Pharmacogenetics and Genomics, 2014)
The CYP3A4*22 (c.522-191 C>T; rs35599367) single nucleotide polymorphism has been associated with lower CYP3A4 mRNA expression and activity. We investigated the association of CYP3A4*22 with the pharmacokinetics of lopinavir through a population pharmacokinetic approach. The minor allele frequency for CYP3A4*22 was 0.035, and seven of 375 patients had a combination of CYP3A4*22 and SLCO1B1 521T>C alleles. Lack of information on the ethnicity in this cohort should be considered as a limitation. However, in the final model, the population clearance was 5.9 l/h and patients with CYP3A4*22/*22 had 53% (P=0.023) lower clearance compared with noncarriers. In addition, the combined effect of CYP3A4*22 with SLCO1B1 521T>C (previously shown to be associated with lopinavir plasma concentration) was analysed. We observed a 2.3-fold higher lopinavir trough concentration (Ctrough) in individuals with CYP3A4*22/*22, a 1.8-fold higher Ctrough with SLCO1B1 521CC and a 9.7-fold higher Ctrough in individuals homozygous for both single nucleotide polymorphisms, compared with noncarriers. A simulated dose-reduction scenario showed that 200/100 mg lopinavir/ritonavir was adequate to achieve therapeutic concentration in individuals with CYP3A4*22/*22 alone or in combination with SLCO1B1 521CC. These data further our understanding of the genetic basis for variability in the pharmacokinetics of lopinavir.

Dependable Online Appointment Booking System for NHIS Outpatient in Nigerian Teaching Hospitals - Adebayo P. Idowu, Olajide O. Adeosun, Kehinde O. Williams (International Journal of Computer Science & Information Technology, 2014)

Determinants of preventive dental practice for children among final year dental students in Nigeria - Folayan, MO; Khami, MR; Folaranmi, N; Orenuga, O; Popoola, BO; Olatosi, O; Ligali, TO; Sofola, OO; A.A. Adeniyi; Esan, A; Osaguona, A (International Journal of Paediatric Dentistry, 2014)

DETERMINATION OF EMPIRICAL RELATIONS BETWEEN GEOELECTRICAL DATA AND GEOTECHNICAL PARAMETERS AT THE SITE OF A PROPOSED EARTH DAM. (Ife Journal of Science, 2014)

Developing Entrepreneurial Competences in University Lecturers: Obafemi Awolowo University Experience - I. O. Abereijo (Kenya College of Accountancy University Journal of Business Management (KJBM), 2014)

Development of a Standard Yorùbá Digital Text Automatic Diacritic Restoration System - Franklin Oladiipo Asahiah (Obafemi Awolowo University, 2014)

Development of a Suit of Virtual Experiments for Physics and Chemistry Undergraduate Laboratories - Oluyemisi Oladayo Satope; Isaiah Oreoluwa Boboye; Akinwale, Olawale Babatunde; Kehinde, Lawrence Olakunle; Olabode Idowu Asubiojo (121st ASEE Annual Conference & Expostion, 2014)

Development of guidelines for the conduct of HIV research monitoring by ethics committees in Nigeria - Haire, B; Folayan, MO; Fleming, J (African Journal of Reproductive Health, 2014)

Differences in sexual behaviour and sexual practices of adolescents in Nigeria based on sex and self-reported HIV status - Folayan, MO; Odetoyingbo, M; Brandon, B; Harrison, A (BMC Reproductive Health, 2014)

Dispute Resolution in Corporate Multi Tenanted Property Management: A case Study - Oladokun, T.T.; Aluko, B. T. (Journal of Corporate Real Estate, 2014)

Diversity of Antibiotic Resistance Genes and Staphylococcal Cassette Chromosome mec elements in Faecal Isolates of Coagulase-Negative Staphylococci from Nigeria. - Vitali, L. A.,; Petrelli, D.,; Lamikanra, A.,; Prenna, M.,; E.O. Akinkunmi (BMC Microbiolgy, 2014)

The Ebola outbreak in Western Africa-ethical obligations for care - Yakubu, A; Folayan, MO; Sani-Gwarzo, N; Nguku, P; Peterson, K; Brandon, B (Journal of Medical Ethics, 2014)

Effect of Cooking and Roasting on Nutritional and Anti- Nutritional Factors in Kenaf (Hibiscus Cannabinus L.) Seed Meal - "K.D. Olawepo"; "O.T. Banjo"; "W.A. Jimoh"; "W.O. Fawole"; "O. Orisasona"; "A.H. Ojo-Daniel" (Food Science and Quality Management, 2014)

THE EFFECT OF DRYING TECHNIQUES ON THE ELASTOPLASTIC PROPERTIES OF LOCALLY PROCESSED MICROCRYSTALLINE CELLULOSE. (2014)

Effect of Internal Control Systems on Operating Performance of Small Business in Lagos Metropolis - MONDAY James, INNEH Godwin, OJO Victoria (International Conference on Accounting, Finance and Management,, 2014)

EFFECT OF MORINGA OLEIFERA SEEDS ON BACTERIAL QUALITY OF DRINKING WATER IN RURAL COMMUNITIES OF ONDO SOUTHWESTERN, NIGERIA (2014)

EFFECT OF SELECTED FACTORS ON THE CURRENT FLOW AND VOLTAGE LOSS AT ELECTRODES DURING ELECTROCHEMICAL TREATMENT OF A LATERITE - Ayodele, A. L.; I.A. Oke; Agbede, O. A. (Ife Journal of Science, 2014)

THE EFFECTS OF ALUMINUM OR SCANDIUM ON THE TOUGHNESS, DENSITY AND PHASE STABILITY OF IRIDIUM, PLATINUM, RHODIUM AND PALLADIUM (2014)