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Folayan, MO, Haire B, Allman D, Yakubu A, MO A.  2018.   Research priorities during infectious disease emergencies in West Africa . BMC Research Notes . 11(1):159.doi:10.1186/s13104-018-3263-3.
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Soyoye, D, Ikem R, Kolawole B, Ala O, Owolabi F, Yusuff O, Ayandele CO.  2016.  Abstract #253: Relationship of Hyperglycaemia and Inflammation to Obesity in Type 2 Diabetes, 2016/05/01. 22:57-58. Abstract
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James, OO, Yetunde OA.  2011.  Acute low dose monosodium glutamate retards novelty induced behaviours in male albino mice. Journal of Neuroscience and Behavioural Health. Vol. 3(4):51-56.
Akinlolu, A, Sule N, Muhammed M, Oyedepo D, Olawole M, Adejumo M, Anigilaje Y, Yusuf M, Omole P, Bukoye T, others.  2021.  Allele Diversity, Haplotype Frequency and Diversity, and Forensic Genotyping of Fulanis and Yorubas Population in North Central Region of Nigeria. Arab Journal of Forensic Sciences & Forensic Medicine. 3:216–230., Number 2 Abstract
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Yasuko, S, Akanmu MA, Masato M, Kazuhiko Y, K.Honda.  2010.  Alpha-fluoromethylhistidine, a histamine synthesis inhibitor, inhibits orexin-induced wakefulness in rats. Behaviourable brain research. Vol. 207:151-154.
Salpietro, V, Dixon CL, Guo H, Bello OD, Vandrovcova J, Efthymiou S, Maroofian R, Heimer G, Burglen L, Valence S et al..  2019.  AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders, 2019. Nature Communications. 10(1) Abstract

AMPA receptors (AMPARs) are tetrameric ligand-gated channels made up of combinations of GluA1-4 subunits encoded by GRIA1-4 genes. GluA2 has an especially important role because, following post-transcriptional editing at the Q607 site, it renders heteromultimeric AMPARs Ca2+-impermeable, with a linear relationship between current and trans-membrane voltage. Here, we report heterozygous de novo GRIA2 mutations in 28 unrelated patients with intellectual disability (ID) and neurodevelopmental abnormalities including autism spectrum disorder (ASD), Rett syndrome-like features, and seizures or developmental epileptic encephalopathy (DEE). In functional expression studies, mutations lead to a decrease in agonist-evoked current mediated by mutant subunits compared to wild-type channels. When GluA2 subunits are co-expressed with GluA1, most GRIA2 mutations cause a decreased current amplitude and some also affect voltage rectification. Our results show that de-novo variants in GRIA2 can cause neurodevelopmental disorders, complementing evidence that other genetic causes of ID, ASD and DEE also disrupt glutamatergic synaptic transmission.

Esan, O, Akinsulore A, Yusuf MB, Adegbehingbe OO.  2017.  Assessment of emotional distress and parenting stress among parents of children with clubfoot in south-western Nigeria. SA Orthopaedic Journal. 16:26–31., Number 2: South African Orthopaedic Association Abstract
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El Tantawi, M, Folayan M, Oginni O, Adeniyi A, Mapayi B, Yassin R, Chukwumah N, Sam-Agudu N.  2021.  Association between mental health, caries experience and gingival health of adolescents in sub-urban Nigeria, 2021/04/30. 21 Abstract
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Folayan, M, Arowolo O, Mapayi B, Chukwumah N, Alade M, Yassin R, El Tantawi M.  2021.  Associations between mental health problems and risky oral and sexual behaviour in adolescents in a sub-urban community in Southwest Nigeria, 2021/08/16. 21 Abstract
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Zhu, Z, Ge T, Xiao M, Yuan H, Wang, T., Liu S, Atere CT, Wu J.  2017.  Belowground carbon allocation and dynamics under rice cultivation depends on soil organic matter content. Plant and Soil. 410:247–258.
Akinyemi, RO, Akinwande K, Diala S, Adeleye O, Ajose A, Issa K, Owusu D, Boamah I, Yahaya IS, Jimoh AO, Imoh L, Fakunle G, Akpalu A, Sarfo F, Wahab K, Sanya E, Owolabi L, Obiako R, Osaigbovo G, Komolafe M, Fawale M, Adebayo P, Olowoyo P, Obiabo Y, Sunmonu T, Chukwuonye I, Balogun O, Adeoye B, Oladele F, Olowoniyi P, Adeyemi F, Lezzi A, Falayi AT, Fasanya M, Ogunwale K, Adeola O, Olomu O, Aridegbe O, Laryea R, Uvere E, Faniyan M, Melikam E, Tagge R, Akpa O, Akinyemi J, Arulogun O, Tiwari HK, Ovbiagele B, Owolabi MO.  2018.  Biobanking in a Challenging African Environment: Unique Experience from the SIREN Project, 2018. Biopreservation and Biobanking. 16(3) Abstract

Africa was previously insufficiently represented in the emerging discipline of biobanking despite commendable early efforts. However, with the Human, Heredity, and Health in Africa (H3Africa) initiative, biorepository science has been bolstered, regional biobanks are springing up, and awareness about biobanks is growing on the continent. The Stroke Investigative Research and Educational Network (SIREN) project is a transnational, multicenter, hospital and community-based study involving over 3000 cases and 3000 controls recruited from 16 sites in Ghana and Nigeria. SIREN aims to explore and unravel the genetic and environmental factors that interact to produce the peculiar phenotypic and clinical characteristics of stroke as seen in people of African ancestry and facilitate the development of new diagnostics, therapeutics, and preventative strategies. The aim of this article is to describe our experience with the development of the procedure for collection, processing, storage, and shipment of biological samples (blood, serum, plasma, buffy coat, red cell concentrates, and DNA) and brain imaging across coordinating and participating sites within the SIREN Project. The SIREN network was initiated in 2014 with support and funding from the H3Africa Initiative. The SIREN Biobank currently has 3015 brain images, 92,950 blood fractions (serum, plasma, red cell concentrates, and buffy coat) accrued from 8450 recruited subjects, and quantified and aliquoted good-quality DNA extracts from 6150 study subjects. This represents an invaluable resource for future research with expanding genomic and trans-omic technologies. This will facilitate the involvement of indigenous African samples in cutting-edge stroke genomics and trans-omics research. It is, however, critical to effectively engage African stroke patients and community members who have contributed precious biological materials to the SIREN Biobank to generate appropriate evidence base for dealing with ethical, legal, and social issues of privacy, autonomy, identifiability, biorights, governance issues, and public understanding of stroke biobanking in the context of unique African culture, language, and belief systems.

Folayan, MO, Brandon B, Yakubu A.  2014.  Black market blood transfusions for Ebola: potential for increases in other infections. Glob Health Action . 7:26356-http://dx.doi.org/10.3402/gha.v7.26356.
Soyoye, D, Ayandele CO, Anizor C, Owolabi F, Ala O, Yusuff O, Ezekpo O, Lawal-Bello A, Adewusi T, Ikem R, Kolawole B.  2017.  Burden of obesity and hypertension in Nigerians with type 2 diabetes mellitus seen in a tertiary health facility, 2017/10/20. Abstract
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Badmus, TA, Adesunkanmi A-RK, Yusuf BM, Oseni GO, Eziyi AK, Bakare TIB, Adetiloye JA, Badmus SA.  2010.  Burden of prostate cancer in southwestern Nigeria. Urology. 76:412–416., Number 2: Elsevier Abstract
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Badmus, TA, Adesunkanmi A-RK, Yusuf BM, Oseni GO, Eziyi AK, Bakare TIB, Adetiloye JA, Badmus SA.  2010.  Burden of prostate cancer in southwestern Nigeria. Urology. 76:412–416., Number 2: Elsevier Abstract
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Yusuff, O, Kolawole B, Ikem R, Soyoye D, Amjo O.  2020.  Cardiovascular Risk Indices and Their Impact on Outcome in Patients with Hyperglycaemic Emergencies in a Nigerian Hospital, 2020/01/20. 112 Abstract

Background:High sensitivity C-reactive protein (hsCRP) and Plasminogen Activator Inhibitor-1 (PAI-1) are recognised independent novel risk factors for cardiovascular disease. Few studies have assessed cardiovascular risk factors in patients with hyperglycaemic emergencies (HE), despite it being a major cause of death in diabetics.
Objective:
The objective of this study was to determine cardiovascular risk indices in patients with hyperglycaemic emergencies and related these with outcome.
Methods:
This cross sectional study involved 45 patients that presented with HE and 45 age and sex matched diabetics without HE who served as controls. Historical features, physical findings and laboratory parameters including hsCRP and PAI-1 were compared between subjects and controls.
Results:
The mean values of serum hsCRP and PAI-1 were significantly higher in patients with HE compared to diabetic control. (49.52 ± 13.6 vs. 2.4 ± 1.35, 51.2 ± 28.7 vs. 33.2 ± 10.7 respectively). Traditional cardiovascular risk factors such as HbA1c, Atherogenic Index and microalbuminuria were also significantly higher in them. Mortality was associated with increasing age, higher values of waist circumference, pulse rate, respiratory rate, hsCRP, Atherogenic index and lower blood pressure and HDL values.
Conclusion:
Cardiovascular risk indices are higher in patients with HE.

Jiang, CM, Duangthip D, Auychai P, Chiba M, Folayan M, Hamama H, Kamnoedboon P, Lyons K, Matangkasombut O, Mathu-Muju K, Mathur V, Mei ML, Morgan M, Poolthong S, Morankar R, Srinivasan M, Takahashi T, Yaklai S, Zhang S, Lo E.  2021.  Changes in Oral Health Policies and Guidelines During the COVID-19 Pandemic. Frontiers in Oral Health, 2021/05/21. 2 Abstract
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Folayan, M, Haire B, Peterson K, Yakubu A, Tegli J, Brown B.  2019.  Chapter 17: Criminalisation and "Reckless" Ebola Transmission: Theorizing Ethical Obligations to Seek Care, 2019/07/01. Abstract
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Oguntoye, O, Ndububa D, Yusuf M, Bolarinwa R, Ayoola O.  2017.  Cholelithiasis in patients with sickle cell anaemia in steady state in Ile-Ife, Nigeria., 2017/01/01. Abstract

Abstract Gallstones are commonly seen in adult patients with sickle cell anemia and they are mainly calcium bilirubinate stones due to chronic hemolysis. This study is aimed to investigate the ultrasonographic prevalence of cholelithiasis(gallstones) among adult patients with sickle cell anemia in steady state attending the Hematology clinic of a federal tertiary health institution in Ile-Ife, Nigeria. Basic demographic data as well as biliary ultrasonography of 50 consecutive sickle cell anemia patients were compared with those of 50 age- and sex-matched subjects with HbAA as controls. Each of the study groups (patients and controls) comprised of 21(42%) males and 29(58%) females. The age range of the patients was 1845years with a mean(±SD) of 27.6±7.607 while that of the controls was 21-43years with a mean(±SD) of 28.0±5.079 (p= 0.746). Amongst the patients, 15(30%) had cholelithiasis and 3(6%) had biliary sludge. All the patients with biliary sludge also had coexisting cholelithiasis. In the control group, one (2%) person had cholelithiasis and one (2%) had biliary sludge. There was a statistically significant difference in the prevalence of cholelithiasis between the patients and controls with p value < 0.001. Cholelithiasis is a common finding in adult patients with sickle cell anemia when compared to the general population. All the patients with biliary sludge had coexisting cholelithiasis, this supports the fact that biliary sludge is a precursor for gallstone formation. Ultrasonography is a useful tool for assessing the biliary tract for gallstones in patients with sickle cell anemia.Keywords: Cholelithiasis, Gallstones, Ultrasonography, Sickle cell anemia.

Oguntoye, OO, Ndububa DA, Yusuf M, Bolarinwa R, Ayoola OO.  2016.  Chronic Liver Disease among Adult Patients with Sickle Cell Anemia in Steady State in Ile-Ife, Nigeria. Journal of Gastroenterology and Hepatology Research. 5:2196–2203., Number 5 Abstract
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Folayan, M, Brown B, Yakubu A, Peterson K, Haire B.  2014.  Compassionate use of experimental interventions in the Ebola outbreak . Lancet. 384(9957):1843-1844.doi:10.1016/S0140-6736(14)61605-6.
Folayan, MO, Allman D, Haire B, Yakubu A, Afolabi MO, Cooper J.  2018.  Considerations for community engagement when conducting clinical trials during infectious disease emergencies in West Africa. Developing World Bioeth. 2018:1-10.
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Yesufu, TK, Enoch-Oghene SO.  2021.  Development of a Technique for Detecting Counterfeit Energy Storage Systems. SMTA International Conference and Exhibition. :313-319., Minneapolis: Surface Mount Technology association (SMTA)
Owolabi, MO, Sarfo F, Akinyemi R, Gebregziabher M, Akpa O, Akpalu A, Wahab K, Obiako R, Ovbiagele B, Sarfo FS, Akinyemi R, Gebregziabher M, Akpa O, Akpalu A, Obiako R, Ovbiagele B, Tiwari HK, Arnett D, Lackland D, Adeoye AM, Akin O, Ogbole G, Jenkins C, Arulogun O, Ryan IM, Armstrong K, Olowoyo P, Komolafe M, Osaigbovo G, Obiabo O, Chukwuonye I, Adebayo P, Adebayo O, Omololu A, Otubogun F, Olaleye A, Durodola A, Olunuga T, Akinwande K, Aridegbe M, Fawale B, Adeleye O, Kolo P, Appiah L, Singh A, Adamu S, Awuah D, Saulson R, Agyekum F, Shidali V, Ogah O, Oguntade A, Umanruochi K, Iheonye H, Imoh L, Afolaranmi T, Calys-Tagoe B, Okeke O, Fakunle A, Akinyemi J, Akpalu J, Ibinaiye P, Agunloye A, Sanni T, Bisi A, Efidi C, Bock-Oruma A, Melikam S, Olaniyan L, Yaria J, Odo CJ, Lakoh S, Ogunjimi L, Salaam A, Oyinloye L, Asaleye C, Sanya E, Olowookere S, Makanjuola A, Oguntoye A, Uvere E, Faniyan M, Akintunde A, Kehinde I, Diala S, Adeleye O, Ajose OA, Onyeonoro U, Amusa AG, Owusu D, Mensah Y, Owolabi L.  2018.  Dominant modifiable risk factors for stroke in Ghana and Nigeria (SIREN): a case-control study, 2018. The Lancet Global Health. 6(4) Abstract

Background: Sub-Saharan Africa has the highest incidence, prevalence, and fatality from stroke globally. Yet, only little information about context-specific risk factors for prioritising interventions to reduce the stroke burden in sub-Saharan Africa is available. We aimed to identify and characterise the effect of the top modifiable risk factors for stroke in sub-Saharan Africa. Methods: The Stroke Investigative Research and Educational Network (SIREN) study is a multicentre, case-control study done at 15 sites in Nigeria and Ghana. Cases were adults (aged ≥18 years) with stroke confirmed by CT or MRI. Controls were age-matched and gender-matched stroke-free adults (aged ≥18 years) recruited from the communities in catchment areas of cases. Comprehensive assessment for vascular, lifestyle, and psychosocial factors was done using standard instruments. We used conditional logistic regression to estimate odds ratios (ORs) and population-attributable risks (PARs) with 95% CIs. Findings: Between Aug 28, 2014, and June 15, 2017, we enrolled 2118 case-control pairs (1192 [56%] men) with mean ages of 59·0 years (SD 13·8) for cases and 57·8 years (13·7) for controls. 1430 (68%) had ischaemic stoke, 682 (32%) had haemorrhagic stroke, and six (<1%) had discrete ischaemic and haemorrhagic lesions. 98·2% (95% CI 97·2–99·0) of adjusted PAR of stroke was associated with 11 potentially modifiable risk factors with ORs and PARs in descending order of PAR of 19·36 (95% CI 12·11–30·93) and 90·8% (95% CI 87·9–93·7) for hypertension, 1·85 (1·44–2·38) and 35·8% (25·3–46·2) for dyslipidaemia, 1·59 (1·19–2·13) and 31·1% (13·3–48·9) for regular meat consumption, 1·48 (1·13–1·94) and 26·5% (12·9–40·2) for elevated waist-to-hip ratio, 2·58 (1·98–3·37) and 22·1% (17·8–26·4) for diabetes, 2·43 (1·81–3·26) and 18·2% (14·1–22·3) for low green leafy vegetable consumption, 1·89 (1·40–2·54) and 11·6% (6·6–16·7) for stress, 2·14 (1·34–3·43) and 5·3% (3·3–7·3) for added salt at the table, 1·65 (1·09–2·49) and 4·3% (0·6–7·9) for cardiac disease, 2·13 (1·12–4·05) and 2·4% (0·7–4·1) for physical inactivity, and 4·42 (1·75–11·16) and 2·3% (1·5–3·1) for current cigarette smoking. Ten of these factors were associated with ischaemic stroke and six with haemorrhagic stroke occurrence. Interpretation: Implementation of interventions targeting these leading risk factors at the population level should substantially curtail the burden of stroke among Africans. Funding: National Institutes of Health.

Idowu, AS, Dada MS, Babalola OT, Yusuf TA, Are EB.  2016.  DTM-Pade solution for heat transfer of hydromagnetic flow over a vertical plate. : Journal of Nigerian Association of Mathematical Physics, Nigerian … Abstract
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