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Sowande, O. A., Talabi, A., Olowookere, S., Adejuyigbe, O., F. O.  2015.  HIV/AIDS pandemic and current practice among Paediatric Surgeons in Nigeria. Afr J Med Med Sci. 44(4):297-302.
Sowande, OA.  2009.  Management of ambiguous genitalia in ile ife Nigeria:challenges and outcome. African Journal of Pediatric Surgery . vol.6:14-18.
Sowole, C, Sote E, Folayan M.  2007.  Dental caries pattern and predisposing oral hygiene factors in Nigerian preschool children . European Archives of Paediatric Dentistry . 8(4):206–210.
Sowole, CA, Owotade FJ, EO S.  2010.  Impact of infant feeding practices on caries experience of preschool chidren in Nigeria. Journal of Clinical Paediatric Dentistry. 34(4):297-301.
Soyoye, D, Kolawole B, Ikem R, Ijarotimi O, Christianah E.  2016.  Metabolic syndrome and component risks-A comparative study of Nigerians with diabetes mellitus and healthy adults, 2016/12/01. 10:39-45. Abstract

Objective: Metabolic syndrome is defined as the constellation of interrelated risk factors of metabolic origin. This constellation of metabolic risk factors in any given individual reflects increased risks of cardiovascular disease, type 2 diabetes and mortality. The combination of these factors in people with diabetes mellitus may also connote increased occurrence of macrovascular and microvascular complications. This study compared the occurrence of metabolic syndrome and its components using the International Diabetes Federation (IDF) criteria in people with diabetes and apparently healthy individuals. Method: One hundred and fifty adult Nigerians with diabetes mellitus and 150 healthy individuals were recruited into this study. Anthropometric and blood pressure measurements were done. Fasting plasma glucose and fasting serum lipid levels were determined. Metabolic syndrome was defined using the IDF criteria. Statistical analyses were done and the characteristics of the two groups were compared. Results: Prevalence of metabolic syndrome among people with diabetes and controls were 73.3% and 14.7% respectively (p = < 0.001) and was higher in women in both groups (male-28.4% vs female-56.6%, p = <0.001). The commonest abnormality among the patients with diabetes, apart from dysglycaemia was reduced high-density lipoprotein cholesterol (HDL-C), present in 84.0% of patients with diabetes. Among control subjects, low HDL-C (67.4%) and elevated waist circumference (WC) (58.7%) were the most common. Mean waist circumference was significantly higher among those with metabolic syndrome compared with those without in both groups. Conclusion: Prevalence of metabolic syndrome and its component abnormalities is high especially among people with diabetes. Efforts geared towards prevention and management of these cardio-metabolic risks should be intensified both in people with diabetes and healthy individuals.

Soyoye, D, Dawha S, Ayoola O, Ibitoye B, Ikem R, Adedeji T.  2018.  Relationship between Renal Doppler Indices and Biochemical indices of Renal Function in Type 2 Diabetes Mellitus, 2018/09/01. 35:189-194. Abstract

Objectives:Diabetic nephropathy is a common complication of diabetes mellitus due to microangiopathy leading to end stage renal disease. This study determined the relationship between renal resistivity index and pulsatility index with biochemical indices of renal function in patients with type 2 diabetes mellitus methods: This study involved 80 adults with type 2 diabetes mellitus. Urinary albumin excretion rate (UAER) and serum creatinine levels were measured, and the estimated glomerular filtration rate (eGFR) was calculated. Right renal resistivity index (RI) and pulsatility index (PI) values were determined.
Results:
Mean renal resistivity index was 0.72±0.06 while the pulsatility index was 1.36 ± 0.24. Resistivity index was positively correlated with albuminuria (r = 0.426; p <0.001) and serum creatinine (r = 0.458; p <0.001), but negatively correlated with eGFR (r = -0.399; p <0.001). There was positive correlation between pulsatility index and albuminuria (r = 0.341; p = 0.002), and serum creatinine (r = 0.478; p = <0.001); and negative correlation between PI and eGFR (r = - 0.359; p = 0.001).
Conclusions:
Renal resistivity index and pulsatility index may provide valuable non-invasive estimate of predicting the presence and severity of renal dysfunction in patients with type 2 diabetes.

Soyoye, D, Ikem R, Kolawole B, Ala O, Owolabi F, Yusuff O, Ayandele CO.  2016.  Abstract #253: Relationship of Hyperglycaemia and Inflammation to Obesity in Type 2 Diabetes, 2016/05/01. 22:57-58. Abstract
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Soyoye, O, Otuyemi O, Kolawole K, Ayoola O.  2018.  Relationship between masseter muscle thickness and maxillofacial morphology in pre-orthodontic treatment patients, 2018/10/01. 16 Abstract

This study investigated the relationship between masseter muscle thickness and cephalometric facial parameters in pre-orthodontic treatment patients. Participants were grouped according to their vertical facial patterns into low, normal, and high angle facial patterns using standardised lateral cephalometric radiograph. Associations between the masseter muscle thickness (measured using ultrasonography) and different vertical facial patterns were analysed. Masseter muscle thickness in low angle subjects were significantly higher than the normal and high angle cases during both relaxation and contraction phases (P < 0.001). Masseter muscle thickness correlated positively with Jarabak ratio and ramus thickness (R1/R2) during both phases, and negatively with LAFH, FMA, MMPA and gonial angle.

Soyoye, D, Ayandele CO, Anizor C, Owolabi F, Ala O, Yusuff O, Ezekpo O, Lawal-Bello A, Adewusi T, Ikem R, Kolawole B.  2017.  Burden of obesity and hypertension in Nigerians with type 2 diabetes mellitus seen in a tertiary health facility, 2017/10/20. Abstract
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Soyoye, D, Abiodun O, Ikem R, Kolawole B, Akintomide A.  2021.  Diabetes and peripheral artery disease: A review, 2021/06/15. 12:827-838. Abstract
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Soyoye, D, Adebayo O, Kolawole B, Ikem R.  2013.  Prevalence and associated risks for metabolic syndrome in nigerians with type 2 diabetes mellitus, 2013/03/01. :1-1. Abstract
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Soyoye, D, Ikem R, Kolawole B, Oluwadiya K, Bolarinwa R, Adebayo O.  2016.  Prevalence and Correlates of Peripheral Arterial Disease in Nigerians with Type 2 Diabetes, 2016/01/01. 2016 Abstract

Background. Peripheral arterial disease (PAD) is a major risk factor for nonhealing foot ulcers in people with diabetes. A number of traditional risk factors have been reported to be associated with PAD; however, there may be a need to consider nontraditional risk factors especially in some vulnerable populations. This study determined the prevalence and risk factors associated with PAD in diabetics. Methods. One hundred and fifty type 2 diabetics and an equal number of age- and sex-matched apparently healthy controls were studied. Assessment of PAD was made using history, palpation of lower limb vessels, and measurement of ankle-brachial index (ABI). Statistically significant differences between categorical and continuous variables were determined using Chi square (χ²) and Student t-tests, respectively. Regression analysis was done to determine the associated risk factors for PAD. Results. Prevalence of PAD using ABI was 22.0% and 8.0% among diabetic and nondiabetic populations, respectively. Peripheral arterial disease was associated with age, male gender, waist circumference, and high-sensitivity C-reactive protein. Conclusion. This study highlights the high prevalence of PAD in people with type 2 diabetes mellitus and in apparently healthy controls; age, male gender, abdominal obesity, and high hs-CRP values were the associated risk factors.

Soyoye, D, Dawha S, Ayoola O, Ibitoye B, Ikem R, Adedeji T.  2018.  Relationship between Renal Doppler Indices and Biochemical indices of Renal Function in Type 2 Diabetes Mellitus, 2018/09/01. 35:189-194. Abstract

Objectives:Diabetic nephropathy is a common complication of diabetes mellitus due to microangiopathy leading to end stage renal disease. This study determined the relationship between renal resistivity index and pulsatility index with biochemical indices of renal function in patients with type 2 diabetes mellitus methods: This study involved 80 adults with type 2 diabetes mellitus. Urinary albumin excretion rate (UAER) and serum creatinine levels were measured, and the estimated glomerular filtration rate (eGFR) was calculated. Right renal resistivity index (RI) and pulsatility index (PI) values were determined.
Results:
Mean renal resistivity index was 0.72±0.06 while the pulsatility index was 1.36 ± 0.24. Resistivity index was positively correlated with albuminuria (r = 0.426; p <0.001) and serum creatinine (r = 0.458; p <0.001), but negatively correlated with eGFR (r = -0.399; p <0.001). There was positive correlation between pulsatility index and albuminuria (r = 0.341; p = 0.002), and serum creatinine (r = 0.478; p = <0.001); and negative correlation between PI and eGFR (r = - 0.359; p = 0.001).
Conclusions:
Renal resistivity index and pulsatility index may provide valuable non-invasive estimate of predicting the presence and severity of renal dysfunction in patients with type 2 diabetes.

Soyoye, DO, Ikem RT, Kolawole BA, Bolarinwa RA, Amjo OO, Yusuff OT, Owolabi FA, Ezekpo OO, others.  2017.  Relationship between C-reactive protein, white blood cell count and metabolic syndrome in Nigerians with type 2 diabetes mellitus. Journal of Diabetes Mellitus. 7:212., Number 03: Scientific Research Publishing Abstract
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Soyoye, D, Ikem R, Kolawole B, Bolarinwa R, Amjo O, Yusuff O, Owolabi F, Ezekpo O.  2017.  Relationship between C-Reactive Protein, White Blood Cell Count and Metabolic Syndrome in Nigerians with Type 2 Diabetes Mellitus, 2017/01/01. 07:212-221. Abstract
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Soyoye, D, Kolawole B, Ikem R, Ugwu E, Soyoye O, Owolabi F, Anozie C, Amjo O, Ogundele O.  2021.  Screening for Diabetes Mellitus and Hypertension in Ile-Ife - A World Diabetes Day Experience, 2021/05/29. 38:434-438. Abstract

Background and objectives:Non-communicable diseases have emerged as major public health concerns in developing nations, where communicable diseases used to be the major contributor to the public health burden. Diabetes and hypertension contribute significantly to this menace, and they are largely undiagnosed in the affected population. We determined the prevalence of previously diagnosed and undiagnosed hypertension and diabetes mellitus in adult Nigerians.
Methods:
Participants who presented in response to advertisement for the study and gave informed consent were recruited using convenience sampling. Data was collected using a proforma to obtain salient medical and social history. Anthropometric and blood pressure measurements were done. Capillary blood was taken for initial glucose measurements. Oral glucose tolerance test (OGTT) was subsequently done in non-diabetics with elevated blood glucose to confirm the diagnosis of diabetes.
Results:
One hundred and thirty-six participants with age range 24 - 90 years were recruited for the study. Participants were mainly females (61.8%). Prevalence of diabetes among study participants was 19.9% (previously diagnosed -16.9% vs undiagnosed - 3.0%) with higher occurrence among males. Hypertension was found in 50.7% of participants; 28.7% were on treatment for hypertension, while 22.0% were newly diagnosed. Diabetes was associated with older age and elevated systolic blood pressure while hypertension was associated with older age, obesity and elevated blood glucose.
Conclusion:
This study showed a high occurrence of diabetes and hypertension among adult Nigerians; hence efforts to address these should be intensified. Targeted screening of people at risk for non-communicable diseases is an added benefit.

Soyoye, D, Kolawole B, Ikem R, Christianah E.  2015.  Relationship between high-sensitivity C-reactive protein and anthropometric indices of obesity, 2015/10/12. Abstract
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Stephen, A, Raji Y.  2011.  Long-Term Administration of Artesunate Induces Reproductive Toxicity in Male Rats, 10. Journal of reproduction & infertility. 12:249-60. Abstract
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Stephen, A, Raji Y.  2011.  Prolonged administration of proguanil induces reproductive toxicity in male rats, 10. The Journal of toxicological sciences. 36:587-99. Abstract
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Stephen, O, Gbenu S, Oyedotun K, Fasakin O, Akindoyin G, Shittu H, Fasasi M, Khandaker M, Osman H, Elesawy B, Kasprzhitskii A, Li Z.  2021.  Fabrication and Characterization of Clay-Polyethylene Composite Opted for Shielding of Ionizing Radiation, 2021/09/03. 11:1058. Abstract

This study fabricated and characterized a self-sustaining hydrogenous content clay-polyethylene composite opted for ionizing radiation shielding. Composites designated A–G were fabricated each containing 0–30 wt% of recycled low density polyethylene (LDPE), respectively. To know the effects of the incorporated LDPE on the morphology, microstructural, compressive strength, thermal property and displacement effect on the vital elements were studied using scanning electron microscopy (SEM), X-ray diffractometry (XRD), universal mechanical testing machine, differential thermal analysis (DTA), Rutherford backscattering (RBS) technique and particle induced X-ray emission (PIXE), respectively. The bulk densities of the clay composites ranged between 1.341 and 2.030 g/cm3. The samples’ XRD analysis revealed similar patterns, with a sharp and prominent peak at angle 2θ equals ~26.11°, which matched with card number 16-0606 of the Joint Committee on Powder Diffraction Standards (JCPDS) that represents Aluminum Silicate Hydroxide (Al2Si2O5(OH)4), a basic formula for Kaolin clay. The compressive strength ranged between 2.52 and 5.53 MPa. The ratio of Si to Al in each composite is about 1:1. The dehydroxylation temperature for samples ranged between 443.23 °C and 555.23 °C.

Subair, OS, Olowookere SA, Akinsulore A, Ibigbami O, Faronbi J, Shabi OM, Adefila VA.  2019.  Relationship between family support and depression symptoms among older women attending a general practice clinic, Lautech Teaching Hospital, Osogbo, Nigeria. Nigerian Journal of Family Practice. 10:12–18., Number 3 Abstract
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Sumonu, TA, Imarhiagbe F, Owolabi LF, Ogunrin OA, Komolafe MA, Ilesanmi OS.  2017.  Cognitive functions in newly diagnosed patients with HIV infection in a tertiary health facility: Assessment using community screening interview for dementia, 2017. eNeurologicalSci. 9 Abstract

Introduction Neurocognitive dysfunction is a detrimental complication of HIV infection. In this study we attempt to characterize the pattern of cognitive dysfunction in a sample of Nigerian patients with newly diagnosed HIV infection. Methods We conducted a prospective study in which 50 patients with newly diagnosed HIV infection were studied along with 50 normal control subjects. The participants were evaluated with the medical history, general, physical and neurological examination. Laboratory evaluation and chest X-Ray were done for all patients. The Community Screening Interview for Dementia (CSID) questionnaire was administered to all the study participants. Results About 70% of the patients were in advanced disease stage. The mean age (SD) of the patients and controls in years were 36.44 ± 8.22 and 35.40 ± 11.53 respectively. More than half (56%) of the patients had secondary level of education (12 years of education). About 20% of the patients had severe neurocognitive impairment while 48% had minor neurocognitive disorder. The patients with HIV infection performed poorly in the domains of language, memory, orientation, attention/calculation and praxis relative to controls (p < 0.05).There were no significant effect of gender, age, sex and level of education on cognitive functions in the patients (p > 0.05) but the presence of opportunistic infections had negative impact on the performances on orientation and total CSID scores in the patients with HIV infection (p < 0.05). Conclusion Patients with newly diagnosed HIV infection have poor cognitive functions when compared to normal controls and some presence of opportunistic infections in the patient is a significant risk factor for cognitive impairment.

Sunday, RM, Ilesanmi OR, Obuotor EM, Ibeh AJ, Ayannuga OA.  2015.  ANTI-DIABETIC EFFECT OF ANTHOCLEISTA VOGELII AQUEOUS ROOT EXTRACT IN STREPTOZOTOCIN INDUCED DIABETIC RATS.. IJS. III:755-763.
Sunmola, A, Adenikinju A, Babatimehin O.  2002.  Costing of HIV/AIDS Prevention Initiatives in Nigeria: the case of social marketing of condoms in Lagos, Oyo and Plateau States.. Costing of HIV/AIDS Prevention Initiatives in Nigeria.. , Ibadan: Nigerian Institute of Social and Economic Research.
Sunmonu, TA, A.Ogunrin O, Imarhiagbe FA, Owolabi LF, Komolafe MA, llesanmi OS.  2016.  Cognitive function in patients with newly diagnosed HIV infection in a tertiary health facility in south – west Nigeria: Assessment using computer-assisted neuropsychological test battery, 2016. eNeurologicalSci. 3 Abstract

Introduction Cognitive dysfunction is common among patients with human immunodeficiency virus (HIV) infection however there are few reports from sub-Saharan Africa. Methods We studied fifty seropositive patients with human immunodeficiency virus (HIV) infection along with fifty matched seronegative control. Medical history taking and general physical and neurological examinations were done for all study participants. Laboratory evaluations and chest X-ray were done for all the patients. The cognitive function was done with the aid of ‘Fepsy’ automated test battery for all the study participants. The data was analyzed with statistical package for social sciences software version 21.0 (SPSS Chicago IL). Result About 70% of the HIV patients were in advanced disease stage. The auditory and visual reaction times, binary choice reaction times, and computerized visual scanning task time were more prolonged in the HIV group (p < 0.05). There were also increased memory accuracy and binary choice task accuracy in the HIV group (p < 0.05). However the vigilance task performance was similar between the two groups (p > 0.05). Among the patients with HIV infection, the presence of anemia and central nervous system toxoplasmosis infection was associated with prolonged auditory and visual reaction times. Conclusion There was a high rate of cognitive dysfunction in patients with HIV infection in this study.