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Sorsa, T, Heikkinen A, Leppilahti J, Tervahartiala T, Nwhator S, Rathnayake N, Mäntylä P, Gieselmann D-R, Netuschil L.  2018.  Active Matrix Metalloproteinase-8: Contributor to Periodontitis and a Missing Link Between Genetics, Dentistry, and Medicine, 2018/01/01. :51-57. Abstract
Akanmu, MA, Adeloye AO, Obutor EM, Adelusola KA, Iwalewa EO, Ukponmwan OE, Lamikanra A.  2010.  Acute and Sub-Chronic toxicity potential effects of Alchornea Cordifolia (Euphorbiaceae) in rats. Nig. J. Nat. Prod.. 14:1-7.
Badejoko, OO, Ijarotimi AO, Awowole IO, Loto OM, Badejoko BO, Olaiya DS, Fatusi AO, Kuti O, Orji EO, Ogunniyi SO.  2012.  Adjunctive rectal misoprostol versus oxytocin infusion for prevention of postpartum hemorrhage in women at risk: a randomized controlled trial.. 2. J Obstet Gynaecol Res.. 38(11):1294-301.
Salawu, L, Bolarinwa RA, Lawal OO, Oyekunle AA, Adeodu O, Adejuyigbe EA, Adelusola KA, Akinola NO, Ndakotsu MA, Durosinmi MA.  2010.  AIDS-related lymphomas in Nigeria an emerging phenomenon. Infectious Agents and Cancer. 5:1–1., Number 1: BioMed Central Abstract
Lähteenmäki, H, Umeizudike K, Heikkinen A, Räisänen I, Rathnayake N, Johannsen G, Tervahartiala T, Nwhator S, Sorsa T.  2020.  aMMP-8 Point-of-Care/Chairside Oral Fluid Technology as a Rapid, Non-Invasive Tool for Periodontitis and Peri-Implantitis Screening in a Medical Care Setting, 2020/08/05. 10:562. Abstract
Salpietro, V, Dixon CL, Guo H, Bello OD, Vandrovcova J, Efthymiou S, Maroofian R, Heimer G, Burglen L, Valence S et al..  2019.  AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders, 2019. Nature Communications. 10(1) Abstract

AMPA receptors (AMPARs) are tetrameric ligand-gated channels made up of combinations of GluA1-4 subunits encoded by GRIA1-4 genes. GluA2 has an especially important role because, following post-transcriptional editing at the Q607 site, it renders heteromultimeric AMPARs Ca2+-impermeable, with a linear relationship between current and trans-membrane voltage. Here, we report heterozygous de novo GRIA2 mutations in 28 unrelated patients with intellectual disability (ID) and neurodevelopmental abnormalities including autism spectrum disorder (ASD), Rett syndrome-like features, and seizures or developmental epileptic encephalopathy (DEE). In functional expression studies, mutations lead to a decrease in agonist-evoked current mediated by mutant subunits compared to wild-type channels. When GluA2 subunits are co-expressed with GluA1, most GRIA2 mutations cause a decreased current amplitude and some also affect voltage rectification. Our results show that de-novo variants in GRIA2 can cause neurodevelopmental disorders, complementing evidence that other genetic causes of ID, ASD and DEE also disrupt glutamatergic synaptic transmission.

Aboderin, OA, Abdu A, Odetoyin BW, Okeke IN, Lawa OO, Ndububa DA, Agbakwuru AE, Lamikanra A.  2007.  Antibiotic resistance of Helicobacter pylori from patients in Ile-Ife, South-west, Nigeria. African health sciences. 7, Number 3: Makerere University Medical School (Uganda) Abstract
Aladesanmi, AJ, Iwalewa EO, Adebajo AC, Akinkunmi EO, Taiwo BJ, Olorunmola FO, Lamikanra A.  2007.  Antimicrobial and Antioxidant Activities of some Nigerian Medicinal plants. African Journal of Traditional, Complementary and Alternative Medicines. Vol. 4(2):173-184.
Aboderin, OA, Abdu A-R, Odetoyin BW, Lamikanra A.  2009.  Antimicrobial resistance in Escherichia coli strains from urinary tract infections. Journal of the national medical association. 101:1268–1273., Number 12: Elsevier Abstract
Aboderin, OA, Abdu A-R, Odetoyin BW, Lamikanra A.  2009.  Antimicrobial {{Resistance}} in {{Escherichia}} Coli {{Strains From Urinary Tract Infections}}. Journal of the National Medical Association. 101:1268–1273., Number 12: {Elsevier} Abstract

Background: An increase in resistance against many different drugs among urinary tract infection (UTI) E coli isolates has been observed in the last 2 decades. This study determined the trends of antimicrobial resistance in E coli to commonly used antibiotics. Methods: The study was conducted in Ile-Ife, southwest Nigeria. Patients with features suggestive of UTI were investigated for presence of significant bacteriuria. Urine isolates were identified. Antimicrobial susceptibility was evaluated in accordance with standard bacteriological methods. Results: Of 442 urine specimens, 158 (35.8%) yielded significant growth, including 41 (25.6%) with E coli. Among the E coli isolates, antimicrobial susceptibility varied in prevalence by agent in descending order as follows: nitrofurantoin (80%), ofloxacin (24%), ciprofloxacin (15%), nalidixic acid (10%), cotrimoxazole (5%), and amoxicillin/clavulanic acid (2%). No isolate was susceptible to amoxicillin, gentamicin, or tetracycline. All were also found to be resistant to at least 3 commonly used drugs. All 25 isolates tested for extendedspectrum ß -lactamase (ESBC) production were found to be presumptive ESBCs producers. Conclusion: The results demonstrate the continued susceptibility of E coli to nitrofurantoin and their widespread and increasing resistance to amoxicillin, gentamicin, cotrimoxazole, ciprofloxacin, ofloxacin, and tetracycline. Nitrofurantoin is a— and, in this locale, perhaps the only— rational drug for empiric treatment of uncomplicated UTI. There is a need for a comprehensive study of the involvement of ESBC-producing E coli in UTI in this environment.

Owolarafe, OK, Adetifa BO, Oyekanmi AC, Lemikan TG, Samuel TM.  2018.  Assessment of fufu production technologies in Ogun State, Nigeria. Arid Zone Journal of Engineering, Technology and Environment. 14:547–558., Number 4 Abstract
Faborode, MO, Owolarafe OK, Lasisi AA, Kasali SA, Oguntuase KS.  2003.  Assessment of seed-oil extraction technology in some selected states in Nigeria. Technovation. 23:545–553., Number 6: Elsevier Abstract
Ligali, TO, Folayan MO, Sheiham A.  2011.  Assessment of time taken to treat dental trauma in Nigerian children . European Archives of Paediatric Dentistry . 12(1):37-40.
Atere, CT, Ge T, Zhu Z, Liu S, Huang X, Shibistova O, Guggenberger G, Wu J.  2019.  Assimilate allocation by rice and carbon stabilisation in soil: effect of water management and Phosphorus fertilisation. Plant and Soil . 445:153–167.
L.J.J, G, W.L A, M E, P.A M, T B, B A, P D, F.K.N A, S.A B, A M, M L, E.A A-A, W D, P T, O J, M D, P A, A.A O, R B, G P-R, M G, S O-Y, G.O O, P.B O, L A-R, F A, T H, P G, M.O O, C.J B, M.L M, A.A A, J.C M, A B.  2016.  Association studies and direct DNA sequencing implicate genetic susceptibility loci in the etiology of nonsyndromic orofacial clefts in sub-Saharan African populations. J Dental Research. 95(11):1245-1256.
Balogun, MO, Omotoso AB, Bell E, Lip GYH, Gemill JD, Hogg KJ, Dunn FG.  1993.  An audit of emergency echocardiography in a district general hospital. International Journal of Cardiology. 41:65-68.
Alatise, OI, Lawal OO, Adisa AO, Arowolo OA, Ayoola OO, Agbakwuru EA, Adesunkanmi ARK, Omoniyi-Esan GO, Olaofe OO.  2012.  Audit of management of gallbladder cancer in a Nigerian tertiary health facility, 2012. 43(3):472-480.: Springer Abstract
Alatise, O, Lawal O, Adisa A, Arowolo O, Ayoola O, Agbakwuru A, Adesunkanmi A, Omoniyi-Esan G, Olaofe O.  2011.  Audit of Management of Gallbladder Cancer in a Nigerian Tertiary Health Facility, 2011/10/26. 43:472-80. Abstract

Gallbladder cancer is a rare malignancy with a variable incidence worldwide. It ranks number eight among all gastrointestinal cancer seen in Nigeria. It is associated with high mortality and morbidity because it is usually diagnosed very late. Adequate surgical resection is the only modality with hope of cure. This requires advanced surgical skills which is quite rare in most developing countries like Nigeria. In this current work, we audit the management and outcome of gallbladder cancer in our hospital, highlighting peculiarity associated with our setting.Consecutive patients managed as cases of gallbladder cancer at Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria between January 1990 and December 2010 were studied retrospectively. Patient demographics, disease and treatment-related variables, and outcomes were analyzed by SPSS version 16.0.
Thirty-one cases of gallbladder cancer were diagnosed over the 21-year period, and this accounts for about 0.3% of all cancer cases seen in our hospital. The median age of this patient cohort was 58 years (range 28 to 79 years). Seventeen (54.8%) patients were age below 60 while 14 (45.2%) were age 60 and above. Twenty-seven patients (87.1%) were female and four (12.9%) were male, with a male to female ratio approximately 1:7. Over 80% of the patients presented with a triad of upper abdominal pain, weight loss, and jaundice. Majority (67.7%) of the patients were diagnosed intraoperatively. Only four patients underwent complete resection as they had radical cholecystectomy including regional lymph node dissection and wedge resection of the gallbladder fossa of the liver. The stages of the resected patients were T3 in three patients and T2 in one. Overall 1- and 5-year survival rates for our entire patient cohort were 32% and 10%, respectively.
In conclusion, this study showed that preoperative diagnosis of gallbladder cancer could be challenging in our environment. A triad of upper abdominal pain, jaundice, and weight loss with judicious use of available radiological modality will increase the chances of making the preoperative diagnosis of the cancer. It also showed that good outcome can be obtained when radical surgery is offered to these few patients within the limitation of resources in few patients with resectable tumor.

Kinyoki, D, Ross J, Lazzar-Atwood A, Munro S, Schaeffer L, Abbasalizad Farhangi M, Abbasi M, Abbastabar H, Abdelalim A, Abdoli A, Abdollahi M, Abdollahpour I, Abdulkader R, Dereje N, Abebo T, Abegaz K, Abolhassani H, Guimarães Abreu L, Abrigo M, Hay S.  2020.  Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017, 2020/08/01. 26:1-1. Abstract
Zhu, Z, Ge T, Xiao M, Yuan H, Wang, T., Liu S, Atere CT, Wu J.  2017.  Belowground carbon allocation and dynamics under rice cultivation depends on soil organic matter content. Plant and Soil. 410:247–258.
Akinyemi, RO, Akinwande K, Diala S, Adeleye O, Ajose A, Issa K, Owusu D, Boamah I, Yahaya IS, Jimoh AO, Imoh L, Fakunle G, Akpalu A, Sarfo F, Wahab K, Sanya E, Owolabi L, Obiako R, Osaigbovo G, Komolafe M, Fawale M, Adebayo P, Olowoyo P, Obiabo Y, Sunmonu T, Chukwuonye I, Balogun O, Adeoye B, Oladele F, Olowoniyi P, Adeyemi F, Lezzi A, Falayi AT, Fasanya M, Ogunwale K, Adeola O, Olomu O, Aridegbe O, Laryea R, Uvere E, Faniyan M, Melikam E, Tagge R, Akpa O, Akinyemi J, Arulogun O, Tiwari HK, Ovbiagele B, Owolabi MO.  2018.  Biobanking in a Challenging African Environment: Unique Experience from the SIREN Project, 2018. Biopreservation and Biobanking. 16(3) Abstract

Africa was previously insufficiently represented in the emerging discipline of biobanking despite commendable early efforts. However, with the Human, Heredity, and Health in Africa (H3Africa) initiative, biorepository science has been bolstered, regional biobanks are springing up, and awareness about biobanks is growing on the continent. The Stroke Investigative Research and Educational Network (SIREN) project is a transnational, multicenter, hospital and community-based study involving over 3000 cases and 3000 controls recruited from 16 sites in Ghana and Nigeria. SIREN aims to explore and unravel the genetic and environmental factors that interact to produce the peculiar phenotypic and clinical characteristics of stroke as seen in people of African ancestry and facilitate the development of new diagnostics, therapeutics, and preventative strategies. The aim of this article is to describe our experience with the development of the procedure for collection, processing, storage, and shipment of biological samples (blood, serum, plasma, buffy coat, red cell concentrates, and DNA) and brain imaging across coordinating and participating sites within the SIREN Project. The SIREN network was initiated in 2014 with support and funding from the H3Africa Initiative. The SIREN Biobank currently has 3015 brain images, 92,950 blood fractions (serum, plasma, red cell concentrates, and buffy coat) accrued from 8450 recruited subjects, and quantified and aliquoted good-quality DNA extracts from 6150 study subjects. This represents an invaluable resource for future research with expanding genomic and trans-omic technologies. This will facilitate the involvement of indigenous African samples in cutting-edge stroke genomics and trans-omics research. It is, however, critical to effectively engage African stroke patients and community members who have contributed precious biological materials to the SIREN Biobank to generate appropriate evidence base for dealing with ethical, legal, and social issues of privacy, autonomy, identifiability, biorights, governance issues, and public understanding of stroke biobanking in the context of unique African culture, language, and belief systems.

Abioye-Kuteyi, EA, Kuku JO, Lateef IC, Ogundipe JA, Mogbeyteren T, Banjo MA.  2011.  Birth Preparedness and Complication Readiness among pregnant women at the three levels of health facilities in Ife Central Local Government, Nigeria.. Journal of Community Medicine and Primary Health Care. . 23(1-2):41-54.
B.O, A, R. FB, O OE, LA B.  2006.  Blindness and visual Impairment among the elderly in Ife -Ijesha Zone of Osun State, Nigeria. Indian Journal of Ophthalmology. 54(1):59-62.
Adisa, AO, Gukas ID, Lawal OO, Adesunkanmi ARK.  2010.  Breast cancer in Nigeria: Is non-adherence to chemotherapy schedules a major factor in the reported poor treatment outcome? The breast journal. 16:206–207., Number 2: Wiley Online Library Abstract