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Izevbekhai, O, Adeagbo B, Olagunju A, Bolaji O.  2017.  Quality of artemisinin-based antimalarial drugs marketed in Nigeria. Trans R Soc Trop Med Hyg. 111(2):90-96. AbstractJournal Website

Background: Artemisinin combination therapy is first-line therapy for treatment of malaria, which is one of the most significant public health problems in Nigeria. With the increasing level of use of these drugs coupled with the emergence of resistance, there is a need for regular post-market surveillance.

Method: Twenty different brands of artesunate-containing antimalarial drugs and 10 brands of artemether-lumefantrine were multi-sourced in the south western part of Nigeria and were subjected to identification, weight uniformity test, and assay using United State pharmacopoeia and International Pharmacopoeia monographs. In vitro-dissolution test of the artemether tablets was also investigated.

Results: All 10 brands (100%) of the artemether-lumefantrine tablets met the assay requirement for artemether and 8 (80%) met the assay requirement for lumefantrine, but only 4 brands (40%) met the requirement for artemether dissolution. One of these brands failed the weight uniformity test. Of the 20 brands of artesunate-containing brands included in this study, 15 (75%) met the standard assay requirement for artesunate and two failed the weight uniformity test.

Conclusions: There is evidence of the presence of substandard artemisinin products in the Nigerian market.

Ispub, Com, Ayoola O, Alao OB, Ibitoye B, SM M.  2007.  Bicornuate Uterus With Associated Bilateral Tubal Blockage And Fibroid Tumors: A Rare Combination Causing Infertility, 2007/01/01. Abstract

A bicornuate uterus is a rare mullerian duct anomaly (MDA) caused by fusion defects of the mullerian duct during embryogenesis.1 They are of clinical significance because they can result in fertility problems ranging from infertility and recurrent abortions to prematurity and malpresentation which increases the perinatal morbidity and mortality rate2. In this paper a case is presented to highlight the hysterosalpingography (HSG) and sonographic findings in a patient with bicornuate uterus with bilateral tubal blockage and submucous fibroid. CASE REPORT A 35-year-old primipara, referred from a private hospital, presented with a 10 year history of infertility following an induced abortion at 8 weeks gestation which was confirmed by an ultrasound examination. There was no history as to suggest a previous pelvic inflammatory disease. The physical examination revealed no remarkable finding and the patient was otherwise in a healthy condition. She was referred to have a hysterosalpingogram and this revealed a complete duplication of the uterine horns with an angle of greater than 105° separating both horns. Several filling defects were consistently seen in the right horn of the uterus indicating fibroid seedlings. Neither of the fallopian tubes were demonstrated (fig. 1). A sonohysterographic examination was done thereafter and this unveiled two divergent uterine horns with separate endometrial cavities and a large fundal cleft (fig. 2), the ovaries were essentially normal. Intravenous urography, which was done to rule out the possibility of a co-existing renal anomalies, was essentially normal. A laparoscopic examination with a dye examination was done following these series of investigations and it revealed two divergent uterine horns and bilateral tubal blockage. Based on the findings, the patient was scheduled for tubal surgery but she defaulted from further management in the hospital as she did not desire a pregnancy to the extent of having a surgery carried out on her. Figure 1 Figure 1: A hysterosalpingogram showing a single cervical canal and a complete duplication of the uterine horns with an angle greater than 105° separating them in bicornuate uterus. Filling defects are also seen (open curved arrows) indicating uterine fibroids.

Ishola, BI, Ayodele KP, Kehinde LO, Akinwale OB, Aboluwarin OO.  2012.  An Improved Operational Amplifier iLab with a Realistic Looking Interface. ASEE Annual Conference & Exposition. :PaperAC2012-4608., San Antonio: ASEEfinal_op_amp_paper_4608.pdf
Ishola, A, Asaleye M, Ayoola O, Loto O, Idowu B.  2016.  Reference Ranges of Fetal Cerebral Lateral Ventricle Parameters by Ultrasonography, 2016/10/17. 38 Abstract

ObjectivesThis study was done to evaluate the normal fetal cerebral lateral ventricle dimensions with transabdominal ultrasonography. The atrial width (AW), ventricle-tochoroid measurement (V-C), ventricle-to-hemisphere ratio (VHR), and combined anterior horn measurement (CAHM) were taken.
Methods
This was a cross-sectional study involving 400 normal singleton pregnant subjects whose gestational ages were between 14 and 40 weeks. Transabdominal sonography was performed to obtain the values of the fetal cerebral lateral ventricle (FCLV) parameters. Data were reported as mean standard deviation (SD) for continuous variables. The degrees of correlation between FCLV parameters and the estimated gestational age (EGA) were obtained using Pearson's correlation. Regression equations were used to generate the reference limits for the FCLV measurements.
Results
The values of AW, V-C measurements and CAHM increased with advancing gestation. The mean values of the AW, V-C and CAHM from 14 to 40 weeks increased from 6.60 0.94 mm to 9.75 0.07 mm (R² = 0.114), 0.80 0.00 mm to 1.90 0.14 mm (R²= 0.266), and 6.95 0.06 mm to 23.07 4.02 mm (R²= 0.692) respectively, while the mean VHR decreased from 61.20 1.60% to 42.84 2.91% (R² = 0.706) over the same period.
Conclusion
The AW, V-C, and CAHM increase, while VHR decreases with advancing gestation.

Ishola, A, Asaleye M, Ayoola O, Loto O, Idowu B.  2016.  Reference Ranges of Fetal Cerebral Lateral Ventricle Parameters by Ultrasonography, 2016/10/17. 38 Abstract

ObjectivesThis study was done to evaluate the normal fetal cerebral lateral ventricle dimensions with transabdominal ultrasonography. The atrial width (AW), ventricle-tochoroid measurement (V-C), ventricle-to-hemisphere ratio (VHR), and combined anterior horn measurement (CAHM) were taken.
Methods
This was a cross-sectional study involving 400 normal singleton pregnant subjects whose gestational ages were between 14 and 40 weeks. Transabdominal sonography was performed to obtain the values of the fetal cerebral lateral ventricle (FCLV) parameters. Data were reported as mean standard deviation (SD) for continuous variables. The degrees of correlation between FCLV parameters and the estimated gestational age (EGA) were obtained using Pearson's correlation. Regression equations were used to generate the reference limits for the FCLV measurements.
Results
The values of AW, V-C measurements and CAHM increased with advancing gestation. The mean values of the AW, V-C and CAHM from 14 to 40 weeks increased from 6.60 0.94 mm to 9.75 0.07 mm (R² = 0.114), 0.80 0.00 mm to 1.90 0.14 mm (R²= 0.266), and 6.95 0.06 mm to 23.07 4.02 mm (R²= 0.692) respectively, while the mean VHR decreased from 61.20 1.60% to 42.84 2.91% (R² = 0.706) over the same period.
Conclusion
The AW, V-C, and CAHM increase, while VHR decreases with advancing gestation.

Isere, A, Adeniran JO, Jaiyeola TG.  2015.  Generalized Osborn loops of order 4n. Acta Universitatis Apulensis Mathematics Informatics. 43 :19-31.
Isere, A, Adeniran JO, Jaiyeola TG.  2021.  Latin quandles and applications to cryptography. Mathematics for Applications. 10(1):37-53..
Isere, A, Adeniran JO, Jaiyeola TG.  2015.  Holomorphy of Osborn loops. Analele Universitatii De Vest Din Timisoara, Seria Matematica-Informatica. 53 (2):81–98.
Isere, A, Adeniran JO, Jaiyeola TG.  2019.  Classification of Osborn loops of order 4n. Proyecciones Journal of Mathematics. 38(1):31-47.
Isenmilla, AE, Babalola O, Obigbesan GO.  1981.  Varietal influence of intercropped cowpea on the growth, yield and water relations of maize. Plant and soil. 62:153–156., Number 1: Springer Abstract
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Iseh, AL, Adegbola AJ, Adeagbo BA.  2017.  Pharmacokinetic Characterization of Piperaquine in Nigerian Healthy Volunteers after Co-administration with a Commercial Brand of Moringa Tea. Journal of Pharmaceutical Research International. :1-10. Abstract
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Isadare, DA, Adeoye MO, Adetunji AR, Oluwasegun KM, Akinluwade KJ.  2014.  Optimization of mechanical properties of age-hardened 6063 aluminium alloy via diffusion annealing. British Journal of Applied Science & Technology. 4:3360., Number 23: SCIENCEDOMAIN International Abstract
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Isadare, AD, Aremo B, Adeoye MO, Olawale OJ, Shittu MD.  2013.  Effect of heat treatment on some mechanical properties of 7075 aluminium alloy. Materials Research. 16:190–194., Number 1: SciELO Brasil Abstract
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Isadare, DA, Adeoye MO, Adetunji AR, Oluwasegun KM, Akinluwade KJ.  2014.  Optimization of mechanical properties of age-hardened 6063 aluminium alloy via diffusion annealing. British Journal of Applied Science & Technology. 4:3360., Number 23: SCIENCEDOMAIN International Abstract
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Isadare, AD, Aremo B, Adeoye MO, Olawale OJ, Shittu MD.  2013.  Effect of heat treatment on some mechanical properties of 7075 aluminium alloy. Materials Research. 16:190–194., Number 1: SciELO Brasil Abstract
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Isadare, DA, Adeoye MO, Adetunji AR, Oluwasegun KM, Akinluwade KJ.  2015.  The Influence of Homogenization Treatment on Aging Response of 6063 Aluminium Alloy. Advances in Research. :1–11. Abstract
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Isadare, D, Adeoye M, Adetunji A, Oluwasegun K, Rominiyi A, Akinluwade K.  2015.  Effect of as-cast cooling on the microstructure and mechanical properties of agehardened 7000 series aluminium alloy. International Journal of Materials Engineering. 5:5–9. Abstract
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Ipinmoroti”, “MO, Akanmu” “OA, Iyiola” “AO, Orisasona” “O.  2017.  Performance of Clarias gariepinus juveniles fed with oven dried maggot (Musca domestica) diets. Journal of Agriculture, Forestry and Fisheries. 16(2):96-100.
Inyang EP, Taleatu BA, Oketayo OO, Mokobia CE, Adenodi RA, Balogun FA.  2011.  Characterizing Thermoluminescence Properties of calcium halophosphate fluorescent coating powder for radiation dosimetry. Journal of Environment Science & Engineering. 53(1):1-6.
Imafidon, C, Akomolafe RO, Ayodele O.  2016.  Sexually Dimorphic Proteinuria in Wistar Rats: Relevance to Clinical Models, 02. Pathophysiology. 23 Abstract
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Imafidon, C, Akomolafe RO.  2019.  Obesity-induced renal injury is associated with oxidative stress via renal ischemia reperfusion injury, 04. Obesity Reviews. 14:100093. Abstract
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Imafidon, C, Akomolafe RO, Sanusi AA, Ogundipe D, Olaoluwa S, Oladele A.  2015.  Polyphenol-rich extract of Vernonia amygdalina (Del.) leaves ameliorated cadmium-induced alterations in feeding pattern and urine volume of male Wistar rats, 12. Journal of Intercultural Ethnopharmacology. 4:284. Abstract
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Imafidon, C, Akomolafe RO, Oluwamayowa O.  2020.  Saliva Renal Function Biomarkers as Alternatives to Plasma Concentrations in Obesity-induced Kidney Injury, 02. Obesity Reviews. :100195. Abstract
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