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Journal Article
Bisi-Johnson, MA, Obi CL, Hattori T, Li S, Kambizi L, Eloff JN, Vasaikar SD.  2011.  Evaluation of the antibacterial and anticancer activities of some South African medicinal plants.. BMC Complementary and Alternative Medicine. 11:14
Omoleke, II, Salawu B, Hassan AO.  2011.  An examination of privatization policy and foreign direct investments in Nigeria. African Journal of Political Science and International Relations. 5(2):72-82.
Olukoga, A, Folayan M, Olukoga T, Harris G, Ogunbodede E.  2011.  Health workers perception of hospital’s institutional structure. American Journal of Tropical Medicine and Public Health . 1(3):79-88.
Schnittger, S, Bacher U, Zander AR, Klyuchnikov E, Haferlach T, Kröger N, Oyekunle A.  2011.  Molecular Diagnostics, Targeted Therapy, and the Indication for Allogeneic Stem Cell Transplantation in Acute Lymphoblastic Leukemia. Advances in Hematology. 2011 AbstractWebsite
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Adjalle, R, Zabelina T, Wolschke C, Zander AR, Bacher U, Held K, Arps S, Oyekunle A, Kroger N, Ayuk F, Klyuchnikov E, Ocheni S.  2011.  Second Allogeneic Stem Cell Transplantation in a Patient with Hypoplastic Myelodysplastic Syndrome following a Primary Diagnosis of Aplastic Anaemia. Acta Haematol. 125:175-178. AbstractWebsite
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Bokemeyer, C, Haferlach T, Kröger N, Zander AR, Dierlamm J, Ocheni S, Schafhausen P, Oyekunle A, Bacher U.  2011.  Unusual Course of Myelodysplastic Syndrome with Presumed Familial Origin. Acta Haematologica. 126:234-237., Number 4 AbstractWebsite

No abstract available

Olukoga, A, Folayan M, Harris G, Ajayi O.  2010.  An analysis of listening skills of healthcare students in Nigeria . West Africa Journal of Medicine . 29(2):104-108.
Tiono, AB, Dicko A, Ndububa DA, Agbenyega T, Pitmang S, Awobusuyi J, Pamba A, Duparc S, Goh LE, Harrell E, Carter N, Ward SA, Greenwood B, Winstanley PA.  2009.  Chlorproguanil-Dapsone-Artesunate versus Chlorproguanil-Dapsone: A randomized, double-blind, phase III trial in African children, adolescents and adults with uncomplicated Plasmodium falciparum malaria. . American Journal of Tropical Medicine & Hygiene. 81:969–978.
Aderemi, HO, Hassan OM, Siyanbola WO, Taiwo K.  2009.  Managing science and technology occupations of women in Nigeria. Journal of technology management & innovation. 4(3):34-45.: Universidad Alberto Hurtado. Facultad de Economía y Negocios Abstract
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Perel, PA, Olldashi F, Muzha I, Filipi N, Lede R, Copertari P, Traverso C, Copertari A, Vergara EA, Montenegro C et al..  2008.  Predicting outcome after traumatic brain injury: Practical prognostic models based on large cohort of international patients, 2008. BMJ. 336(7641) Abstract

Objective: To develop and validate practical prognostic models for death at 14 days and for death or severe disability six months after traumatic brain injury. Design: Multivariable logistic regression to select variables that were independently associated with two patient outcomes. Two models designed: "basic" model (demographic and clinical variables only) and "CT" model (basic model plus results of computed tomography). The models were subsequently developed for high and low-middle income countries separately. Setting: Medical Research Council (MRC) CRASH Trial. Subjects: 10 008 patients with traumatic brain injury. Models externally validated in a cohort of 8509. Results: The basic model included four predictors: age, Glasgow coma scale, pupil reactivity, and the presence of major extracranial injury. The CT model also included the presence of petechial haemorrhages, obliteration of the third ventricle or basal cisterns, subarachnoid bleeding, midline shift, and non-evacuated haematoma. In the derivation sample the models showed excellent discrimination (C statistic above 0.80). The models showed good calibration graphically. The Hosmer-Lemeshow test also indicated good calibration, except for the CT model in low-middle income countries. External validation for unfavourable outcome at six months in high income countries showed that basic and CT models had good discrimination (C statistic 0.77 for both models) but poorer calibration. Conclusion: Simple prognostic models can be used to obtain valid predictions of relevant outcomes in patients with traumatic brain injury.

Kuliya-Gwarzo, A, Ibegbulam OG, Mamman A, Raji AA, Akingbola TS, Mabayoje VO, Ocheni S, Tanko Y, Amusu OA, Akinyanju OO, Ndakotsu MA, Kassim DO, Arewa OP, Bolarinwa RAA, Olaniyi JA, Okocha CE, Akinola NO, Bamgbade OO, Adediran IA, Salawu L, Faluyi JO, Oyekunle AA, Okanny CC, Akanmu S, Halim DNK, Bazuaye GN, Enosolease ME, Nwauche CA, Ogbe OP, Wakama TT, Durosinmi MA.  2008.  The use of Imatinib mesylate (Glivec) in Nigerian patients with chronic myeloid leukemia.. Cellular Therapy and Transplantation. 1:10.3205/ctt-2008-en-000027.01., Number 2 Abstract

Objectives: To assess response and toxicity to Imatinib mesylate (Glivec) in Nigerian Patients with chronic myeloid leukemia. Methods: From August 2003 to August 2007, 98 consecutive, consenting patients, 56 (57%) males and 42 (43%) females, median age 36 years (range, 11-65 years) diagnosed with CML, irrespective of disease phase received Imatinib at a dose of 300-600mg/day at the OAU Teaching Hospitals, Nigeria. Response to therapy was assessed by clinical, haematological and cytogenetic parameters. Blood counts were checked every two weeks in the first three months of therapy. Chromosome analysis was repeated sixth monthly. Overall survival (OS) and frequency of complete or major cytogenetic remission (CCR/MCR) were evaluated. Results: Complete haematologic remission was achieved in 64% and 83% of patients at one and three months, respectively. With a median follow-up of 25 months, the rates of CCR and MCR were 59% and 35% respectively. At 12 months of follow-up, OS and progression- free survival (PFS) were 96% and 91%, respectively. Achievement of CR at six months was associated with significantly better survival (p = 0.043).Conclusions: Compared to treatment outcome with conventional chemotherapy and alpha interferon, as previously used in Nigeria, the results obtained with this regimen has established Imatinib as the first-line treatment strategy in patients with CML, as it is in other populations, with minimal morbidity.

Akinpelu, V, Amusa Y, Eziyi J, Haastrup AA, Ameye S.  2007.  Oesophageal denture impaction producing Horner's syndrome: A case report, 2007/10/01. 121:e17. Abstract

Dentures in the oesophagus have been associated with various complications; however, Horner's syndrome following denture impaction has not been reported in our locality.Horner's syndrome developed in a 26-year-old woman following accidental swallowing of an upper denture which then became impacted in the oesophagus. The denture was retrieved via cervical oesophagotomy. The syndrome abated completely by the seventh day post-surgery. The clinical features of Horner's syndrome are discussed.
Compression of the stellate ganglion, with resultant Horner's syndrome, can be associated with denture impaction in the cervical oesophagus.

Desa, E, Berque J, Odido M, Mazzilli, S., Holland, G., Hoguane A., Ittekkot, V., Kayak, S., Salami, A. T., Torres PO.  2007.  The Business of Capacity-Development, In: UN Group on Earth Observations (ed),. (The Full Picture, Tudor Rose, Geneva):pp.243-245.
New, M, Hewitson B, Stephenson D, Tsiga A, Kruger A, Manhique A, Gomez B, Coelho S, Masisi D, Kululanga E, Mbambalala E, Adesina F, Saleh H, Kanyanga JK, Adosi J, Bulane L, Fortunata L, Mdoka M, Lajoie R.  2006.  Evidence of trends in daily climate extremes over southern and west Africa, 2006/07/27. 111 Abstract

[ 1] There has been a paucity of information on trends in daily climate and climate extremes, especially from developing countries. We report the results of the analysis of daily temperature ( maximum and minimum) and precipitation data from 14 south and west African countries over the period 1961 - 2000. Data were subject to quality control and processing into indices of climate extremes for release to the global community. Temperature extremes show patterns consistent with warming over most of the regions analyzed, with a large proportion of stations showing statistically significant trends for all temperature indices. Over 1961 to 2000, the regionally averaged occurrence of extreme cold ( fifth percentile) days and nights has decreased by - 3.7 and - 6.0 days/decade, respectively. Over the same period, the occurrence of extreme hot (95th percentile) days and nights has increased by 8.2 and 8.6 days/decade, respectively. The average duration of warm ( cold) has increased ( decreased) by 2.4 (0.5) days/decade and warm spells. Overall, it appears that the hot tails of the distributions of daily maximum temperature have changed more than the cold tails; for minimum temperatures, hot tails show greater changes in the NW of the region, while cold tails have changed more in the SE and east. The diurnal temperature range (DTR) does not exhibit a consistent trend across the region, with many neighboring stations showing opposite trends. However, the DTR shows consistent increases in a zone across Namibia, Botswana, Zambia, and Mozambique, coinciding with more rapid increases in maximum temperature than minimum temperature extremes. Most precipitation indices do not exhibit consistent or statistically significant trends across the region. Regionally averaged total precipitation has decreased but is not statistically significant. At the same time, there has been a statistically significant increase in regionally averaged daily rainfall intensity and dry spell duration. While the majority of stations also show increasing trends for these two indices, only a few of these are statistically significant. There are increasing trends in regionally averaged rainfall on extreme precipitation days and in maximum annual 5-day and 1-day rainfall, but only trends for the latter are statistically significant.

New, M, Hewitson B, Stephenson D, Tsiga A, Kruger A, Manhique A, Gomez B, Coelho S, Masisi D, Kululanga E, Mbambalala E, Adesina F, Saleh H, Kanyanga JK, Adosi J, Bulane L, Fortunata L, Mdoka M, Lajoie R.  2006.  Evidence of trends in daily climate extremes over southern and west Africa, 2006/07/27. 111 Abstract

[ 1] There has been a paucity of information on trends in daily climate and climate extremes, especially from developing countries. We report the results of the analysis of daily temperature ( maximum and minimum) and precipitation data from 14 south and west African countries over the period 1961 - 2000. Data were subject to quality control and processing into indices of climate extremes for release to the global community. Temperature extremes show patterns consistent with warming over most of the regions analyzed, with a large proportion of stations showing statistically significant trends for all temperature indices. Over 1961 to 2000, the regionally averaged occurrence of extreme cold ( fifth percentile) days and nights has decreased by - 3.7 and - 6.0 days/decade, respectively. Over the same period, the occurrence of extreme hot (95th percentile) days and nights has increased by 8.2 and 8.6 days/decade, respectively. The average duration of warm ( cold) has increased ( decreased) by 2.4 (0.5) days/decade and warm spells. Overall, it appears that the hot tails of the distributions of daily maximum temperature have changed more than the cold tails; for minimum temperatures, hot tails show greater changes in the NW of the region, while cold tails have changed more in the SE and east. The diurnal temperature range (DTR) does not exhibit a consistent trend across the region, with many neighboring stations showing opposite trends. However, the DTR shows consistent increases in a zone across Namibia, Botswana, Zambia, and Mozambique, coinciding with more rapid increases in maximum temperature than minimum temperature extremes. Most precipitation indices do not exhibit consistent or statistically significant trends across the region. Regionally averaged total precipitation has decreased but is not statistically significant. At the same time, there has been a statistically significant increase in regionally averaged daily rainfall intensity and dry spell duration. While the majority of stations also show increasing trends for these two indices, only a few of these are statistically significant. There are increasing trends in regionally averaged rainfall on extreme precipitation days and in maximum annual 5-day and 1-day rainfall, but only trends for the latter are statistically significant.

New, M, Hewitson B, Stephenson D, Tsiga A, Kruger A, Manhique A, Gomez B, Coelho S, Masisi D, Kululanga E, Mbambalala E, Adesina F, Saleh H, Kanyanga JK, Adosi J, Bulane L, Fortunata L, Mdoka M, Lajoie R.  2006.  Evidence of trends in daily climate extremes over southern and west Africa, 2006/07/27. 111 Abstract

[ 1] There has been a paucity of information on trends in daily climate and climate extremes, especially from developing countries. We report the results of the analysis of daily temperature ( maximum and minimum) and precipitation data from 14 south and west African countries over the period 1961 - 2000. Data were subject to quality control and processing into indices of climate extremes for release to the global community. Temperature extremes show patterns consistent with warming over most of the regions analyzed, with a large proportion of stations showing statistically significant trends for all temperature indices. Over 1961 to 2000, the regionally averaged occurrence of extreme cold ( fifth percentile) days and nights has decreased by - 3.7 and - 6.0 days/decade, respectively. Over the same period, the occurrence of extreme hot (95th percentile) days and nights has increased by 8.2 and 8.6 days/decade, respectively. The average duration of warm ( cold) has increased ( decreased) by 2.4 (0.5) days/decade and warm spells. Overall, it appears that the hot tails of the distributions of daily maximum temperature have changed more than the cold tails; for minimum temperatures, hot tails show greater changes in the NW of the region, while cold tails have changed more in the SE and east. The diurnal temperature range (DTR) does not exhibit a consistent trend across the region, with many neighboring stations showing opposite trends. However, the DTR shows consistent increases in a zone across Namibia, Botswana, Zambia, and Mozambique, coinciding with more rapid increases in maximum temperature than minimum temperature extremes. Most precipitation indices do not exhibit consistent or statistically significant trends across the region. Regionally averaged total precipitation has decreased but is not statistically significant. At the same time, there has been a statistically significant increase in regionally averaged daily rainfall intensity and dry spell duration. While the majority of stations also show increasing trends for these two indices, only a few of these are statistically significant. There are increasing trends in regionally averaged rainfall on extreme precipitation days and in maximum annual 5-day and 1-day rainfall, but only trends for the latter are statistically significant.

Akanmu, MA, Olayiwola G, Ukponmwan OE, Honda K.  2005.  Acute Toxicity and Sleep-wake eeg Analysis of Stachtarpheta Cayennensis (Verbenaceae) in Rodents. Afr. J. Trad. CAM. Vol. 2(3):222-232.
i. Falade, OS, O O, Harwood CE, Adewusi SRA.  2005.  Chemical Composition and Starch Hydrolysis of Acacia-colei and Acacia-tumida Seeds. Cereal Chemistry. 82(5):479-484.1.pdf
Peterson, J, Dwyer J, Bhagwat S, Haytowitz D, Holden J, Eldridge A, Beecher G, Aladesanmi AJ.  2005.  Major flavonoids in dry tea. J.Food Composition and Analysis. 18:487-501.
Akanmu, MA, Honda K.  2005.  Selective stimulation of orexin receptor type 2 promotes wakefulness in freely behaving rats . Journal of Brain research. 1048:138-145.
Olldashi, F, Muzha I, Filipi N, Lede R, Copertari P, Traverso C, Copertari A, Vergara EA, Montenegro C, De Huidobro RR et al..  2004.  Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): Randomised placebo-controlled trial, 2004. The Lancet. 364(9442) Abstract

Background Corticosteroids have been used to treat head injuries for more than 30 years. In 1997, findings of a systematic review suggested that these drugs reduce risk of death by 1-2%. The CRASH trial—a multicentre international collaboration—aimed to confirm or refute such an effect by recruiting 20 000 patients. In May, 2004, the data monitoring committee disclosed the unmasked results to the steering committee, which stopped recruitment. Methods 10 008 adults with head injury and a Glasgow coma score (GCS) of 14 or less within 8 h of injury were randomly allocated 48 h infusion of corticosteroids (methylprednisolone) or placebo. Primary outcomes were death within 2 weeks of injury and death or disability at 6 months. Prespecified subgroup analyses were based on injury severity (GCS) at randomisation and on time from injury to randomisation. Analysis was by intention to treat. Effects on outcomes within 2 weeks of randomisation are presented in this report. This study is registered as an International Standard Randomised Controlled Trial, number ISRCTN74459797. Findings Compared with placebo, the risk of death from all causes within 2 weeks was higher in the group allocated corticosteroids (1052 [21·1%] vs 893 [17·9%] deaths; relative risk 1·18 [95% CI 1·09-1·27]; p=0·0001). The relative increase in deaths due to corticosteroids did not differ by injury severity (p=0·22) or time since injury (p=0·05). Interpretation Our results show there is no reduction in mortality with methylprednisolone in the 2 weeks after head injury. The cause of the rise in risk of death within 2 weeks is unclear.

Raji, Y, Hammed AI, Adesanwo JK, Ogunwande IA.  2000.  Antiulcerogenic Effects of Tylophora conspicua in Male Rats. PHYTOTHERAPY RESEARCH. 14:378–380. Phytotherapy Research
He, K, Timmermann BN, Aladesanmi AJ, Zeng L.  1996.  A Biflavonoid from Dysoxylum lenticellare Gillespie, Phytochemistry. 42:1199-1201.
Balogun, MO, Omotoso AB, Bell E, Lip GYH, Gemill JD, Hogg KJ, Dunn FG.  1993.  An audit of emergency echocardiography in a district general hospital. International Journal of Cardiology. 41:65-68.
Aladesanmi, AJ, Hoffmann JJ.  1991.  Grindelane Derivatives by Microbial Transformation, Phytochemistry. 30:1847-1848.