Publications

Export 235 results:
Sort by: Author Title [ Type  (Asc)] Year
Book
San-Martin, L, CASTAO SEIQUER SR A, Ribas Pérez D, Ogunbodede E.  2014.  Undergraduate Geriatric Dentistry Programs in Spain, 2014/06/26. Current Research in Dentistry. 6 Abstract

Objective: Over the past few decades, the world has experienced a gradual increase in the percentage of elderly people aged 65 years and over. As this elderly population increases, evidence suggests that their demand for dental services would increase. The increasing population of the elderly population in Spain has underlined the need for the dental profession to take pay particular attention to the oral health needs of older patients. The aim of this report is to present a preliminary assessment of the undergraduate Geriatric Dentistry programs in Spanish dental schools.Method: Study participants included all the dental schools in Spain (n=19). Using a simple, 12-item questionnaire, information was collected regarding the geriatric dental education programs from the official websites of all the schools.
Results: Only 42% (n=8) of schools offered a specific geriatric dentistry course. No significant differences were found in the proportion of public and private dental schools with geriatric dentistry departments (p=0.1312).
Conclusion: More studies on the curriculum content, design, implementation and evaluation of geriatric dentistry programs at the undergraduate level should be developed. Research must also focus on assessing the access and improvement to the oral care of the elderly population. Dental schools, organizations, local and state governments need to work together, using a multidisciplinary approach, in responding to the unmet needs of the elderly population.

San-Martin, L, CASTAO SEIQUER SR A, Ribas Pérez D, Ogunbodede E.  2014.  Undergraduate Geriatric Dentistry Programs in Spain, 2014/06/26. Current Research in Dentistry. 6 Abstract

Objective: Over the past few decades, the world has experienced a gradual increase in the percentage of elderly people aged 65 years and over. As this elderly population increases, evidence suggests that their demand for dental services would increase. The increasing population of the elderly population in Spain has underlined the need for the dental profession to take pay particular attention to the oral health needs of older patients. The aim of this report is to present a preliminary assessment of the undergraduate Geriatric Dentistry programs in Spanish dental schools.Method: Study participants included all the dental schools in Spain (n=19). Using a simple, 12-item questionnaire, information was collected regarding the geriatric dental education programs from the official websites of all the schools.
Results: Only 42% (n=8) of schools offered a specific geriatric dentistry course. No significant differences were found in the proportion of public and private dental schools with geriatric dentistry departments (p=0.1312).
Conclusion: More studies on the curriculum content, design, implementation and evaluation of geriatric dentistry programs at the undergraduate level should be developed. Research must also focus on assessing the access and improvement to the oral care of the elderly population. Dental schools, organizations, local and state governments need to work together, using a multidisciplinary approach, in responding to the unmet needs of the elderly population.

San-Martin, L, Castaño A, Bravo M, Tavares M, Niederman R, Ogunbodede E.  2013.  Dental sealant knowledge, opinion, values and practice of Spanish dentists, 2013/02/08. BMC oral health. 13:12. Abstract

BackgroundMultiple guidelines and systematic reviews recommend sealant use to reduce caries risk. Yet, multiple reports also indicate that sealants are significantly underutilized. This study examined the knowledge, opinions, values, and practice (KOVP) of dentists concerning sealant use in the southwest region of Andalusia, Spain. This is a prelude to the generation of a regional plan for improving children’s oral health in Andalusia.
Methods
The survey’s target population was dentists working in western Andalusia, equally distributed in the provinces of Seville, Cadiz, and Huelva (N=2,047). A convenience sample of meeting participants and meeting participant email lists (N=400) were solicited from the annual course on Community and Pediatric Dentistry. This course is required for all public health sector dentists, and is open to all private sector dentists. Information on the dentist’s KOVP of sealants was collected using four-part questionnaire with 31, 5-point Likert-scaled questions.
Results
The survey population demographics included 190 men (48%) and 206 women (52%) with an average clinical experience of 10.6 (± 8.4) years and 9.3 (± 7.5) years, respectively. A significant sex difference was observed in the distribution of place of work (urban/suburb) (p=0.001), but no sex differences between working sector (public/private). The mean ± SD values for each of the four KOVP sections for pit and fissure sealants were: knowledge = 3.57 ± 0.47; opinion = 2.48 ± 0.47; value = 2.74 ± 0.52; and practice = 3.48 ± 0.50. No sex differences were found in KOVP (all p >0.4). Independent of sex: knowledge statistically differed by years of experience and place of work; opinion statistically differed by years of experience and sector; and practice statistically differed by years of experience and sector. Less experienced dentists tended to have slightly higher scores (~0.25 on a Likert 1–5 scale). Statistically significant correlations were found between knowledge and practice (r=0.44, p=0.00) and between opinion and value (r=0.35, p=0.00).
Conclusions
The results suggest that, similar to other countries, Andalusian dentists know that sealants are effective, have neutral to positive attitudes toward sealants; though, based on epidemiological studies, underuse sealants. Therefore, methods other than classical behavior change (eg: financial or legal mechanisms) will be required to change practice patterns aimed at improving children's oral health.

San-Martin, L, Castaño A, Bravo M, Tavares M, Niederman R, Ogunbodede E.  2013.  Dental sealant knowledge, opinion, values and practice of Spanish dentists, 2013/02/08. BMC oral health. 13:12. Abstract

BackgroundMultiple guidelines and systematic reviews recommend sealant use to reduce caries risk. Yet, multiple reports also indicate that sealants are significantly underutilized. This study examined the knowledge, opinions, values, and practice (KOVP) of dentists concerning sealant use in the southwest region of Andalusia, Spain. This is a prelude to the generation of a regional plan for improving children’s oral health in Andalusia.
Methods
The survey’s target population was dentists working in western Andalusia, equally distributed in the provinces of Seville, Cadiz, and Huelva (N=2,047). A convenience sample of meeting participants and meeting participant email lists (N=400) were solicited from the annual course on Community and Pediatric Dentistry. This course is required for all public health sector dentists, and is open to all private sector dentists. Information on the dentist’s KOVP of sealants was collected using four-part questionnaire with 31, 5-point Likert-scaled questions.
Results
The survey population demographics included 190 men (48%) and 206 women (52%) with an average clinical experience of 10.6 (± 8.4) years and 9.3 (± 7.5) years, respectively. A significant sex difference was observed in the distribution of place of work (urban/suburb) (p=0.001), but no sex differences between working sector (public/private). The mean ± SD values for each of the four KOVP sections for pit and fissure sealants were: knowledge = 3.57 ± 0.47; opinion = 2.48 ± 0.47; value = 2.74 ± 0.52; and practice = 3.48 ± 0.50. No sex differences were found in KOVP (all p >0.4). Independent of sex: knowledge statistically differed by years of experience and place of work; opinion statistically differed by years of experience and sector; and practice statistically differed by years of experience and sector. Less experienced dentists tended to have slightly higher scores (~0.25 on a Likert 1–5 scale). Statistically significant correlations were found between knowledge and practice (r=0.44, p=0.00) and between opinion and value (r=0.35, p=0.00).
Conclusions
The results suggest that, similar to other countries, Andalusian dentists know that sealants are effective, have neutral to positive attitudes toward sealants; though, based on epidemiological studies, underuse sealants. Therefore, methods other than classical behavior change (eg: financial or legal mechanisms) will be required to change practice patterns aimed at improving children's oral health.

Caleb, M.  2013.  CV. View My CV
De Vries(nci, J, Murtomaa H, Butler(com M, Cherrett(nci H, Ferrillo(nci P, Ferro M, Gadbury-Amyot C, Haden K, Manogue M, Mintz J, E. Mulvihill(nci J, Murray(nci B, Nattestad A, Nielsen(nci D, Ogunbodede E, Parkash H, Plasschaert(nci F, T. Reed(nci M, L. Rupp(com R, Shanley(nci D.  2008.  The Global Network on Dental Education: a new vision for IFDEA, 2008/02/15. European Journal of Dental Education. 12:167-175. Abstract

The advent of globalization has changed our perspectives radically. It presents increased understanding of world affairs, new challenges and exciting opportunities. The inequitable distribution and use of finite energy resources and global warming are just two examples of challenges that can only be addressed by concerted international collaboration. Globalization has become an increasingly important influence on dentistry and dental education. The International Federation for Dental Educators and Associations (IFDEA) welcomes the challenges it now faces as a player in a complex multifaceted global community. This report addresses the new circumstances in which IFDEA must operate, taking account of the recommendations made by other working groups. The report reviews the background and evolution of IFDEA and describes the extensive developments that have taken place in IFDEA over the past year with the introductions of a new Constitution and Bylaws overseen by a newly established Board of Directors. These were the consequence of a new mission, goals and objectives for IFDEA. An expanded organization is planned using http://www.IFDEA.org as the primary instrument to facilitate the exchange of knowledge, programmes and expertise between colleagues and federated associations throughout the world, thereby promoting higher standards in oral health through education in low-, middle- and high-income countries of the world. Such aspirations are modified by the reality and enormity of poverty-related global ill health.

C Mathabathe, N, Rudolph M, Ogunbodede E, Smuts B.  2004.  From didactic teaching to participatory learning. An innovative approach, 2004/04/01. SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging. 59:60-3. Abstract

A course in Public Oral Health is currently offered by the Division of Public Oral Health (POH) to students in their final (6th year) of study for the degree of Bachelor of Dental Science. A fundamental aspect of this project was to shift the teaching methods from didactic to a participatory, student-centred approach, based on current local and international trends in medical, dental and general education. In 1999 the course covering core Public Health topics was presented over a period of 20 weeks to 49 students who were divided into three groups. Staff members were trained in participatory, student-centred teaching methods. An evaluation of students and staff was conducted at the end of the course. Results show that students were satisfied with the teaching methods employed and commended the Division on the organisation of the course. Students were unhappy with the amount of reading required in preparation for weekly seminars. They felt that the course was inappropriately positioned in their final year of study, due to pressure of achieving quotas for the clinical courses. Nevertheless, the main objectives of the Public Oral Health course were achieved through the adoption of a participatory, student-centred teaching approach.

Ayoh`OMIDIRE, F[elix, dos Santos D[oredes M(MD), Castillo LE.  2004.  Contos crioulos da Bahia/Creole Tales from Bahia/Àkójopò Ìtàn Àtenudénu Ìran Omo Odùduwà ni Ilè Bahia (Brasíì). , Salvador: Núcleo Cultural Níger Okán, Projeto Cultural e Desenvolvimento Comunitário no Brasil. Salvador: Níger Okán
C Mathabathe, N, Rudolph M, Ogunbodede E.  2000.  Managed health care and dentists in the Gauteng province, 2000/04/01. SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging. 55:132-5. Abstract

Managed health care (MHC) has emerged in South Africa as an alternative system to control the cost of health care. Fears, negative perceptions and much uncertainty have surrounded this issue since its introduction in South Africa. The purpose of this study was to assess the understanding, perceptions and opinions of dentists residing in the Gauteng province about the emergence, benefits, impact, and future of MHC in South Africa. Eighty-six dentists (21.5%) out of the sample population of 400 responded to the questionnaire. The majority (66.7%) of the respondents perceived MHC to be a threat to their practices, with most feeling that MHC will interfere with the doctor-patient relationship. Forty-two per cent of the respondents were of the opinion that MHC will not succeed in South Africa. The results suggest that this sample of dentists do not consider MHC to be an alternative to the existing fee-for-service system. The introduction of MHC in South Africa is mostly based on models used in the USA, which might not be appropriate in the unique South African environment.

Mickenautsch, S, Rudolph M, Ogunbodede E, Chikte U.  1999.  Oral health among Liberian refugees in Ghana, 1999/05/01. East African medical journal. 76:206-11. Abstract

To promote community involvement in the provision of oral health services.The project consisted of a four-week training course in oral health for selected refugees, an oral health survey based on WHO guidelines and conducted by the refugees themselves and the provision of oral health care services to the community by the trained refugees.
Liberian refugee camp, Gomoa Buduburam in Ghana.
Liberian refugees of all ages.
Twelve refugees were given short term training in oral health. In the oral health survey, 196 refugees were clinically examined for dental caries, periodontal disease and malocclusion.
DMFT (for dental caries), CPITN (for periodontal disease), and malocclusion scores for selected subjects. Also clinical services rendered.
Oral health survey revealed a mean age (+/- SD) of 25.7 (+/- 9.5) years. Only thirty nine (19.9%) of the subjects were caries-free, and total DMFT was 2.5 +/- 2.2. Based on the CPITN, 107 (54.6%) required oral hygiene instructions (OHI), and 41 (20.9%) required prophylactic scaling with OHI. Forty four (22.5%) of the subjects had normal occlusion and 152 (77.5%) mild to severe malocclusion. Periodontal (75.5%), prosthetic (52.5%) interventions and extractions (34.2%) constituted the bulk of the treatment needs required. Clinical treatment was rendered by the trained refugees to 846 patients over a twelve month period.
Relief programmes for refugees should emphasise a primary health care approach, focusing on prevention, based on appropriate technology, and promoting involvement by the refugee community in the provision of services.

Book Chapter
Mary Nyasimi, Ayansina Ayanlade, Catherine Mungai, Mercy Derkyi, Jegede MO.  2018.  Inclusion of Gender in Africa’s Climate Change Policies and Strategies. Handbook of Climate Change Communication. : Springer
Peterson, K, Folayan MO, Chigwedere E, Nthete E.  2017.  Saying no to PrEP research in Malawi: what constitutes ‘failure’ in offshored HIV prevention research. Nicola Bulled (ed). Advances in Critical Medical Anthropology. Thinking through resistance: a study of public oppositions to contemporary global health practice. . , 711 Third Avenue, New York, NY10017.: Routledge.
Kehinde, LO, Chen X, Ayodele KP, Akinwale OB.  2012.  Developing Remote Labs for Challenged Educational Environments. Internet Accessible Remote Laboratories: Scalable E-Learning Tools for Engineering and Science Disciplines. , Hershey, PA
Conference Paper
Lal, C, DiSanto G, Caputo M, Panighel M, Taleatu BA, Goldoni A, Jain IP.  2014.  Electronic Structure of Fe3Si on Si(100) Substrates, Dec.. AIP Proceedings. , India
Siccardi, M, Olagunju A, Simiele M, D’Avolio A, Calcagno A, Perri GD, Bonora S, Owen A.  2014.  Relative genetic contribution to the pharmacokinetics of commonly prescribed antiretrovirals (Abstract #504), 3-6 March. 21st Conference on Retroviruses and Opportunistic Infections (CROI). , Boston, MA, USA Abstract

Background: Antiretroviral pharmacokinetics is characterised by broad variability influenced by numerous factors affecting absorption, distribution, metabolism and elimination. Recently, a relative genetic contribution (rGC) of 0.904 (0.64 – 0.97) was reported for nevirapine (NVP) AUC0-6h (Micheli et al, Pharmacogenet Genomics, 2013). The aim of this study was to assess the Cmin rGC for a panel of antiretroviral drugs to rank agents according to the degree to which heritability influences their pharmacokinetics.

Methods: Patients from the Therapeutic Drug Monitoring Registries of the University of Turin and the University of Liverpool were included in the study. Inclusion criteria for both cohorts were as follows: receiving boosted lopinavir (LPV/r, 300/100 mg twice daily), boosted atazanavir (ATV/r 300/100 mg once daily), unboosted ATV (ATV, 400mg once daily), efavirenz (EFV, 600 mg once daily), NVP (400 mg once daily) or raltegravir (RAL, 400 mg twice daily), age>18 years, not receiving drugs known to contribute to drug-drug interactions. Plasma drug concentrations were determined using validated HPLC or LC-MS/MS methods. Intrapatient (SDw) and interpatient (SDb) variability were measured in patients with plasma concentrations available from more than one occasion. The rGC was calculated using the following equation: 1-(1/F) where F= SDb2/SDw. Statistical significance for genetic contribution was calculated using F-test, α = 0.05.

Results: A total of 211 patients were included in the study, 37 receiving LPV/r, 24 receiving ATV/r, 24 receiving ATV, 82 receiving EFV, 20 receiving NVP and 24 receiving RAL. SDw and SDb were 38% and 43% for LPV/r (n = 37), 49% and 50% for ATV/r (n = 24), 54% and 104% for ATV (n = 24), 33% and 60% for EFV (n = 82), 19% and 44% for NVP (n = 20), and 81% and 95% for RAL (n = 24), respectively. Mean with 95% CI rGC was calculated to be 0.35 (0.06-0.55) for LPV/r, 0.15 (0-0.6) for ATV/r, 0.55 (0.35 – 0.7) for ATV, 0.78 (0.68 – 0.85) for EFV, 0.82 (0.62-0.91) for NVP and 0.08 (0-0.56) for RAL (Figure). Genetic contribution was statistically significant (p<0.05) for ATV, EFV and NVP.

Discussion: The rank order for genetic contribution to variability in Cmin for the study drugs was NVP > EFV > ATV > LPV/r > ATV/r > RAL indicating class specific differences exist. Interestingly, these data indicate that ritonavir reduces the genetic contribution to variability in ATV Cmin presumably through inhibition of gene products such as CYP3A4 and ABCB1. Drugs with higher rGC scores may represent better candidates for pharmacogenetic studies.

Lal, C, Jain IP, DiSanto G, Caputo M, Panighel M, Taleatu BA, Goldoni A.  2013.  XPS study of 2H-TPP at Fe/Si(111) system, Dec. 2012. AIP Proceedings. , India
Olabanji, SO, Omobuwajo OR, Adebajo AC, Ceccato D, Buoso MC, Moschini G.  2013.  PIXE analysis of some anti-diabetic medicinal plants in Nigeria, 3-8th Mar, 2013. PIXE 2013: International Conference on Particle-Induced X-Ray Emission for Technology and Global Development. , Gramado, RS (Brazil)
Siccardi, M, Olagunju A, Curley P, Hobson J, Khoo S, Back D, Owen A.  2013.  Prediction of Etravirine Pharmacogenetics Using a Physiologically Based Pharmacokinetic Approach (Abstract #888), 3-6 March. 20th Conference on Retroviruses and Opportunistic Infections (CROI). , Atlanta, GA, USA Abstract

Background: Etravirine (ETV) is metabolized by CYP3A4 and CYP2C19. A known inhibitor of CYP2C19, omeprazole increases ETV exposure by 41%. Since CYP2C19*2 (rs4244285) can affect CYP2C19 expression there is the potential to alter ETV exposure. We previously showed utility of physiologically based PK (PBPK) models for predicting genetic associations and drug-drug interactions from in vitro data in the absence of clinical data. The aim of this study was to develop a PBPK model for ETV PK and predict effects of CYP2C19*2 in virtual human subjects.

Methods: A new open-source PBPK model was developed with algorithms describing covariance between demographics and organ size, hepatic metabolism, induction of metabolic enzymes, expression, and mechanisms regulating absorption and distribution. In vitro data describing chemical properties as well as absorption, distribution, metabolism, and elimination of ETV were used to simulate ETV PK at 200 mg twice daily in 200 virtual subjects. Simulated PK parameters, such as Ctrough, Cmax, and AUC were compared with observed values from the literature. The impact of CYP2C19*2 on ETV clearance was then determined by altering CYP2C19 expression in the model. All simulations were conducted using the differential equation solver Berkeley Madonna.

Results: Simulated PK variables at steady state (mean ± SD) were Ctrough (293 ± 185 ng/mL), Cmax (363 ± 207 ng/mL), and AUC (4005 ± 2364 ng/mL.h), in agreement with previous clinical PK data: Ctrough (297 ± 391 ng/mL) and AUC (4522 ± 4710 ng/mL.h). Simulated mean ETV clearance (CL/F), volume of distribution, and ka were 59 ± 31 (L/h), 14.9 ± 3.6 L/kg, and 0.17 ± 0.011 hr–1, respectively. ETV (CL/F) was predicted to be 62 ± 35, 53 ± 31, and 41 ± 28 L/h for CYP2C19 *1/*1, *1/*2 and *2/*2, respectively.

Conclusions: The IVIVE model predicted in vivo PK of ETV in individuals with different CYP2C19 genotypes. The frequency of CYP2C19*2 has a higher frequency in Asian populations which may underpin heterogeneity in ETV exposure. Mechanistic evaluation of disposition can inform PBPK models and prediction of pharmacogenetic associations. IVIVE may be particularly helpful for the rational design of novel regimens for use in stratified populations. This includes prediction of optimal dose and dosing regimen, selection of partner drugs and validation of the likely overall pharmacological effect of discrete molecular processes, all of which can and should be tested in clinical studies.

Panighel, M, DiSanto G, Caputo M, Lal C, Taleatu BA, Goldoni A.  2013.  Review of 2H-tetraphenylporphyrins metalation in ultra-high vacuum on metal surfaces. IOP Conf. Series. , Trieste, Italy
Conference Proceedings
Panighel, M, DiSanto G, Caputo M, Lal C, Taleatu BA, Goldoni A.  2013.  Review of 2H-Tetraphenylporphyrins Metalation in Ultra-high Vacuum on Metal Surfaces. IOP Conference Series. :1088-1742., England: Journal of Physics
Akinwale, OB, Kehinde LO, Ayodele KP, Jubril AM, Jonah OP, Ilori O, Chen X.  2009.  A LabVIEW-based on-line robotic arm for students’ laboratory. 2009 ASEE Annual Conference & Exposition. :Paper2009-1179., Austin, Texas: ASEE
Database
Sartorius, B, VanderHeide J, Yang M, Goosmann E, Hon J, Haeuser E, Chowdhury MAK, Perkins S, Jahagirdar D, Schaeffer L, Serfes A, LeGrand K, Abbastabar H, Hailemariam Z, Eshete A, Abu-Gharbieh E, Accrombessi M, Adebayo O, Adegbosin A.  2021.  Subnational mapping of HIV incidence and mortality among individuals aged 15–49 years in sub-Saharan Africa, 2000–18: a modelling study, 2021/06/05. Abstract
n/a
Journal Article
Folayan, M, Arowolo O, Mapayi B, Chukwumah N, Alade M, Yassin R, El Tantawi M.  2021.  Associations between mental health problems and risky oral and sexual behaviour in adolescents in a sub-urban community in Southwest Nigeria, 2021/08/16. 21 Abstract
n/a
Amarquaye, G, Arrow P, Bansal K, Bedi R, Campus G, Chen KJ, Chibinski A, Chinzorig T, Crystal Y, Duangthip D, Ferri M, Folayan M, Garidkhuu A, Hamama H, Jirarattanasopa V, Kemoli A, Leal S, Leelataweewud P, Chu C-H.  2021.  Global Oral Health Policies and Guidelines: Using Silver Diamine Fluoride for Caries Control, 2021/07/01. 2:685557. Abstract
n/a
Chen, KJ, Duangthip D, Gao S, Huang F, Anthonappa R, Oliveira B, Turton B, Durward C, El Tantawi M, Attia D, Heima M, Muthu S, Maharani D, Folayan M, Phantumvanit P, Sitthisettapong T, Innes N, Crystal Y, Ramos-Gomez F, Chu C-H.  2021.  Oral Health Policies to Tackle the Burden of Early Childhood Caries: A Review of 14 Countries/Regions, 2021/06/01. 2:670154. Abstract
n/a