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Christianah, E, Kolawole B, Soyoye D, Adebayo J, Ikem R.  2020.  Influence of gender on the distribution of type 2 diabetic complications at the obafemi awolowo teaching hospital, Ile-Ife, Nigeria, 2020/04/20. 20:294-307. Abstract

Background:Sex specific differences appear particularly relevant in the management of type 2 DM.
We determined gender specific differences in cardio-metabolic risk, microvascular and macrovascular complications in patients with type 2 diabetes.
Four hundred type 2 diabetes patients, males and females, matched for age and disease duration were recruited from the diabetes clinic. Relevant clinical and laboratory information were obtained or performed.
190(47.5%) were male and 210 (52.5%) were female respectively. The mean age of the study population was 60.6 + 9.93 years. Women had higher prevalence of hypertension (and obesity. Mean total cholesterol was significantly higher in women but men were more likely to achieve LDL treatment goals than women (69.5% vs 59.0%, p<0.05). More women (47.1% & 31.4%) reached glycaemic goals of <10mmol/l for 2HPP and HBA1c of <7.0%.There were no gender differences in the distribution of microvascular and macrovascular complications (p>0.05) but women were more likely to develop moderate and severe diabetic retinopathy (p= 0.027).
Women with T2DM had worse cardiometabolic risk profile with regards to hypertension, obesity and lipid goals. Men achieved therapeutic goals less frequently than did women in terms of glycaemia. Microvascular and macrovascular complications occurred commonly in both sexes.

Christianah, E, Soyoye D, Adebayo J, Kolawole B, Ikem R.  2016.  Glycaemic and other treatment goals attainment in patients with type 2 diabetes mellitus at the Obafemi Awolowo University Teaching Hospital, Ile-Ife South-West, Nigeria, 2016/06/01. 10:67-79. Abstract

ABSTRACTBackground: The findings from previous studies as well as diabetes treatment guidelines show that Diabetes Mellitus (DM)
treatment extends beyond glycaemic control. This includes lowering lipids, blood pressure, and weight control with diet and
increase in physical activity. This study determined the proportion of Type 2 DM patients reaching glycaemic, blood pressure,
and lipid goals and related the presence of some complications to treatment goal attainment.
Method: This cross-sectional descriptive study involved three hundred (300) Type 2 diabetic patients consecutively recruited
from the diabetes clinic of OAUTHC, Ile-Ife. Relevant clinical information and physical examination were carried out.
Venous blood was collected to determine fasting plasma glucose, 2 hour postprandial glucose, glycated haemoglobin, total
cholesterol, low density lipoprotein, high density lipoprotein and triglycerides. Urine was collected for albumin and proteinuria.
Treatment goals were set using ADA criteria: HBA1c < 7%, blood pressure <130/80mmHg, total cholesterol < 200mg/dl,
triglycerides < 150mg/dl, LDL <100mg/dl and HDL >40mg/dl (1.1mmol/l) in males and >50mg/dl (1.3 mmol/l) in
Results: A total of 300 patients with Type 2 Diabetes mellitus were recruited into the study. One hundred and six (35.3%)
were males and 194(64.7%) were females. Their mean age was 61.17 +10.5 years (62.0+ 10.9 years for males and 60.7+10.3years
females). Majority of the patients (44%) were traders.
Of the 300 participants, 8.3% achieved the combined optimal treatment goals for HBA1c, blood pressure and lipids. Seventy
(23.3%) achieved the HBA1c targets of <7.0%, 45.0 % attained the ADA blood pressure goal of <130/80mmHg and 37.0%
achieved optimal lipid goals. Bi-variate analysis showed statistically significant relationship between treatment targets attained
and reduction in the frequency of diabetic retinopathy, neuropathy, nephropathy and peripheral vascular diseases (p <0.001).
Logistic regression analysis showed that patients with short duration of DM, good compliance with medication, and 2 hours
postprandial blood glucose of less than 10mmol/l were more likely to attain HBA1c goal of <7.0%.
Conclusions: The proportion of patients not attaining treatment goals was high and majority of these patients bore a
greater burden of chronic diabetic complications.

Chukwuani, MC, Bolaji OO, Onyeji CO, Makinde ON, Ogunbona FA.  2004.  Evidence for increased metabolism of chloroquine during the early third trimester of human pregnancy.. Tropical Medicine and International Health. 9(5):1-5.
Chukwumah, NM, Kolawole KA, Folayan MO, Oyedele TA, Oziegbe EO, Onyejaka N, Agbaje HO, Oshomoji V.  2018.  Non-nutritive oral habits, age, sex, socioeconomic status and infant feeding practices in children in sub-urban Nigeria . IOSR Journal of Medical and Dental Sciences . 17(3):7-13.
Chukwumah, NM, Folayan MO, Oziegbe E, Umweni A.  2016.  Impact of dental caries and its treatment on the quality of life of 12-15 year old adolescents in Benin, Nigeria. International Journal of Paediatric Dentistry . 26(1):66-76..doi:10.1111/ipd.12162..
CIroham, O, Ogunba OA.  2008.  Client Influence on Valuation: Its effects on Lagging of Commercial Property Investments. Journal of the Faculty of Environmental Sciences, University of Lagos . 6(2):55-71.
CIroham, O, Ogunba OA.  2010.  “A Search for an Acceptable Margin of Valuation Error: A Case Study of Valuers and their Clients in Nigeria” . Sri Lankan Journal of Real Estate. Department of Estate Management and Valuation, Faculty of Management Studies & Commerce, University of Sri Jayawardenepura, Nugegoda, Sri Lanka.. (4):54-73.
Coker, M, Folayan M, Michelow I, Oladokun R, Torbunde N, Sam-Agudu N.  2020.  Things must not fall apart: the ripple effects of the COVID-19 pandemic on children in sub-Saharan Africa, 2020/09/24. 89 Abstract
Collaborators, GBD, Murray C, Cristiana A, Abbas K, Abbasi M, Abbasi-Kangevari M, Abd-Allah F, Abdollahi M, Abedi P, Abedi A, Abolhassani H, Aboyans V, Guimarães Abreu L, Abrigo M, Abu-Gharbieh E, Haimed A, Medina-Solís CE, I. Abushouk A, Acebedo A, Bekuma T.  2020.  Five insights from the Global Burden of Disease Study 2019, 2020/10/17. 396:1135-1159. Abstract
Cooper, KA, Adelekan DA, Esimai OA, Cleves N-CA, Thuruham DT.  2002.  ) Lack of influence of red palm oil on severity on malarial infection in preschool Nigerian infants.. Transactions of the Royal Society of Tropical Medicine and Hygiene. 96:216-223.
Cyril-Olutayo, M, Ajayi D, Odunowo O.  2020.  ETHNO MEDICINAL SURVEY AND EVALUATION OF TWO RECIPES USED IN MANAGING SICKLE CELL DISEASE IN ILE-IFE COMMUNITY OF OSUN-STATE, NIGERIA, 12. African Journal of Traditional, Complementary and Alternative Medicines. 17:37-54. Abstract
Cyril-Olutayo, M, Elujoba AA, Durosinmi M.  2009.  Antisickling properties of the fermented mixture of Carica papaya Linn and Sorghum bicolor (L.) Moench, 04. African Journal of Pharmacy and Pharmacology. 3 Abstract
Cyril-Olutayo, M, Agbedahunsi J, Akinola N.  2018.  Studies on the effect of a nutritious vegetable, Telfairia occidentalis, on HbSS blood, 07. Journal of Traditional and Complementary Medicine. 9 Abstract
Cyril-Olutayo, M, Adeyemo T, Oriola A, Agbedahunsi J, Muse W.  2020.  Bioactivity directed isolation of antisickling compounds from Cnidoscolus acontifolius Mill.) I.M . Johnst leaf extract, 09. Journal of Pharmacy & Pharmacognosy Research. 8:580-590. Abstract
Cyril-Olutayo, M, Agbedahunsi JM, Akinola NO.  2018.  In vitro Evaluation of Moringa oleifera Leaf Extracts Used in Managing Sickle Cell Patients in South West Nigeria, 10. Nigerian Journal of Pharmaceutical Research. 14:69-79. Abstract


Cyril-Olutayo, M, Elujoba AA, Durosinmi M.  2008.  Antisickling properties of Carica papaya Linn, 01. 1:56-66. Abstract
Cyril-Olutayo, M, Adewoyin F, Ogunyemi A.  2018.  Evaluation of the Effects of Clerodendrum polycephalum Baker Leaf Extracts on Sickle Red Blood Cells, 06. European Journal of Medicinal Plants. 24:1-10. Abstract
Cyril-Olutayo, M, Akinola N, Adeyemo T, Oyemitan I, Bejide R, Agbedahunsi J.  2020.  In vitro Antisickling and Sub Chronic Toxicity Studies of the Ethanol Extract of Cnidoscolus aconitifolius in Wistar Rats, 05. 9:344. Abstract
Cyril-Olutayo, M, Adewoyin F, Ogunyemi A.  2018.  Evaluation of the Effects of Clerodendrum polycephalum Baker Leaf Extracts on Sickle Red Blood Cells, 06. European Journal of Medicinal Plants. 24:1-10. Abstract
Cyril-Olutayo, M, Omonkhua A, Akanbi O.  2013.  Effects of Anogeissus leiocarpus on Haematological Parameters of Mice Infected with Plasmodium berghei, 03. Journal of Plant Studies. 2 Abstract