Prolonged Febrile Illness Due to {{CTX}}-{{M}}-15 Extended- Spectrum {$\beta$}-Lactamase-Producing {{Klebsiella}} Pneumoniae Infection in {{Nigeria}}

Citation:
Aboderin, A, Adefehinti O, Odetoyin B, Olotu A, Okeke I, Adeodu O.  2012.  Prolonged Febrile Illness Due to {{CTX}}-{{M}}-15 Extended- Spectrum {$\beta$}-Lactamase-Producing {{Klebsiella}} Pneumoniae Infection in {{Nigeria}}. African Journal of Laboratory Medicine. 1

Abstract:

We report on an 8-year-old patient with septicaemia unresponsive to therapy for five weeks. Undetected, extended-spectrum {$\beta$}-lactamase (ESBL) production by the infecting Klebsiella strain was regarded as responsible for treatment failure. Intravenously administered imipenem during the sixth week led to sustained resolution of fever. Resource-limited hospitals can incur prohibitive costs from ESBL-producer infections because of diagnostic limitations and consequent treatment failure involving prolonged supportive therapy.

Notes:

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