Publications

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2022
2020
Odediran, SA, Awosode KE, Adegoke TA, Odebunmi KA, Oladunjoye BB, Obasanya AA, Omilani IM, Soyinka KT, Ugbo JU, Ogunleke AJ, Adesida SA, Adebajo AC.  2020.  Combinations of Chrysophyllum albidum and Citrus aurantifolia as Antimalarial Agents and their Effects on Orthodox Antimalarial Drugs in Mice. Ann Complement Altern Med. 2020; 2 (1). 2(1):Article1007:1-9. Abstract

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Nwafor, PA, Genesis EU, Dare ST, Adeyemi OI, Odediran SA, Adebajo AC.  2020.  Evaluation of aphrodisiac activities of four Nigerian ethnomedicinal plants. Annals of Complementary and Alternative Medicine (Ann Complement Altern Med.) . 2(1):Article1009;1-9.
2019
Ayoola, MD, Adebajo AC, Zotor FB, Pinkoane MG.  2019.  Justifying Antidiabetic Ethnomedicinal Claim of Senecio biafrae through Its Antihyperglycemic and Anti-Oxidant Activities. Ann Complement Altern Med. 2019; 1 (2). 1006 Abstract
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2017
Ayoola, MD, Adebajo AC, Obuotor EM, Oladapo TO, Fleischer TC.  2017.  Anti-hyperglycaemic and anti-oxidant activities of five Nigerian antidiabetic plants, jun. Journal of Science and Technology (Ghana). 37(2):71–84., Number 2: African Journals Online ({AJOL}) AbstractWebsite

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Adeyemi, OI, Ige OO, Agbede E, Adebajo AC.  2017.  The effect of Tardalafil on the aphrodisiac properties of Allium sativum and Allium cepa using behavioural models in rats. Nigerian Journal of Natural Products and Medicine . 21:14-20.
Aiyelabola, T, Akinkunmi E, Ojo I, Obuotor E, Adebajo C, Isabirye D.  2017.  Syntheses, Characterization, Resolution, and Biological Studies of Coordination Compounds of Aspartic Acid and Glycine. Bioinorganic Chemistry and Applications. 4(1):Article2956145:1-15. Abstract

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2016
Adeyemi, OI, Ige OO, Olowu AA, Adebajo AC.  2016.  Combination with Tadalafil reduces the aphrodiasiac activity of Cola acuminata and Garcinia cola in rats. Nigerian Journal of Natural Products and Medicine . 20:167-173.
2014
Adebajo, AC, Odediran SA, Aliyu FA, Nwafor PA, Nwoko NT, Umana US.  2014.  In vivo antiplasmodial potentials of the combinations of four Nigerian antimalarial plants. Molecules. 19(9):13136-13146., Number 9 Abstract

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Odediran, SA, Elujoba AA, Adebajo AC.  2014.  Influence of formulation ratio of the plant components on the antimalarial properties of MAMA decoction. Parasitology Research. 113(5):1977-1984., Number 5 Abstract

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Olabanji, SO, Adebajo AC, Omobuwajo OR, Ceccato D, Buoso MC, Moschini G.  2014.  PIXE analysis of some Nigerian anti-diabetic medicinal plants (II). Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms. 318:187-190., Number PART A Abstract

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Adebajo, AC, Famuyiwa FG, Aliyu FA.  2014.  Properties for sourcing Nigerian larvicidal plants. Molecules. 19(6):8363-8372., Number 6 Abstract

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2013
Olabanji, SO, Omobuwajo OR, Adebajo AC, Ceccato D, Buoso MC, Moschini G.  2013.  PIXE analysis of some anti-diabetic medicinal plants in Nigeria, 3-8th Mar, 2013. PIXE 2013: International Conference on Particle-Induced X-Ray Emission for Technology and Global Development. , Gramado, RS (Brazil)
Adebajo, AC, Ayoola MD, Obagbemi OR, Obuotor EM, Ogunsina OM, Pinkoane M, Verspohl EJ.  2013.  Antihyperglycaemic and Anti-oxidant Activities of Eugenia uniflora Leaf: Evaluation of Ethnomedical Claims {IV}, 1–5th Sept, 2013. 61st Conference of the GA, Planta Medica; 79(13): PE2. 79, Number 13, Institut für Pharmazeutische Biologie und Phytochemie, WWU, Münster, Germany: Georg Thieme Verlag {KG} Abstract

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Adebajo, AC, Famuyiwa FG, John JD, Idem ES, Aliyu AF, Adeoye AO.  2013.  Determination of Properties Useful for Sourcing Nigerian Phytolarvicides, 1–5th Sept, 2013. 61st Conference of the Gesellschaft für Arzneipflanzenforschung (GA),Planta Medica; 79(13): PE11. 79, Number 13, Institut für Pharmazeutische Biologie und Phytochemie, WWU, Münster, Germany: Georg Thieme Verlag {KG} Abstract

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Adebajo, AC, Rukunga GM, Schmidt TJ, Verspohl EJ.  2013.  Evaluation of Nigerian ethnomedical plants for anti-infective and antidiabetic properties, 1–5th Sept, 2013. 61st Conference of the Gesellschaft für Arzneipflanzenforschung (GA), Planta Medica; 79(13): SL21. 79, Number 13, Institut für Pharmazeutische Biologie und Phytochemie, WWU, Münster, Germany: Georg Thieme Verlag {KG} Abstract

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Adebajo, AC, Aliyu AF, Odediran SA, Nwafor PA, Nwoko TN, Umana SU, Adeoye AO.  2013.  In vivo antiplasmodial activities of four Nigerian medicinal plants, 1–5th Sept, 2013. 61st Conference of the Gesellschaft für Arzneipflanzenforschung (GA), Planta Medica; 79(13): PE3. 79, Number 13, Institut für Pharmazeutische Biologie und Phytochemie, WWU, Münster, Germany: Georg Thieme Verlag {KG} Abstract

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Famuyiwa, FG, Adebajo AC.  2013.  Larvicidal Activities of the Leaves of Eugenia uniflora L. (Myrtaceae), 1–5th Sept, 2013. 61st Conference of the Gesellschaft für Arzneipflanzenforschung (GA), Planta Medica; 79(13): PE12. 79, Number 13, Institut für Pharmazeutische Biologie und Phytochemie, WWU, Münster, Germany: Georg Thieme Verlag {KG} Abstract

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Adebajo, AC, Odediran SA, Rukunga GM, Ademowo OG, Schmidt TJ, Verspohl EJ.  2013.  Evaluation of ethnomedical claims: Antiplasmodial and anti-hyperglycaemic activities of Gongronema latifolium root and stem, 1-5th Sept, 2013. 61st Conference of the Gesellschaft für Arzneipflanzenforschung (GA), Planta Medica; 79(13): PE1. 79, Number 13, Institut für Pharmazeutische Biologie und Phytochemie, WWU, Münster, Germany: Georg Thieme Verlag {KG} Abstract

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Adebajo, AC, Ayoola MD, Obagbemi OR, Obuotor EM, Ogunsina MO, Verspohl EJ.  2013.  Antihyperglycaemic and antioxidant activities of Eugenia uniflora leaf: Evaluation of ethnomedical claims IV. Ife Journal of Science & Technology . 1(1):1-18.
Adebajo, AC, Ayoola MD, Odediran SA, Aladesanmi AJ, Schmidt TJ, Verspohl EJ.  2013.  Evaluation of Ethnomedical Claim III: Anti-hyperglycemic activities of Gongronema latifolium root and stem. Journal of Diabetes. 5(3):336-343., Number 3 AbstractWebsite

Abstract Background The insulinotropic activity of the combined root and stem of Gongronema latifolium (Asclepiadaceae) was evaluated to justify its African ethnomedicinal use in the management of diabetes. Methods A methanolic extract and its chromatographic fractions (A1–A6) were tested for glucose-reducing and in vitro insulin-stimulating abilities using glucose-loaded rats and INS-1 cells, respectively. In vivo insulin-releasing activities for the significantly (P < 0.05) active antihyperglycemic A5 and A6 and in vitro insulinotropic activity of the C1 fraction and its isolated constituents were also similarly determined. Results The extract (100 mg/kg) had higher in vivo antihyperglycemic activity than the individual A1–A6, indicating a synergistic effect of the plant constituents. Higher in vivo insulin release in response to A5 (100 mg/kg) than A6, agreed with their in vivo antihyperglycemic activities and confirmed insulin release as a mechanism of action of the plant. Compared with 5.6 mmol/L glucose (negative control), the extract and the A3, A6, and C1 (all at 100.0 μg/mL) elicited significantly higher in vitro insulin release that was similar to that of glibenclamide (1.0 μg/mL; P > 0.05). Fraction C1 yielded a 1:1 mixture of α-amyrin and β-amyrin cinnamates (1a:1b), lupenyl cinnamate (2), lupenyl acetate (3), and two unidentified triterpenoids, Y and Z. The 1a:1b mixture (100.0 μg/mL) demonstrated the highest insulinotropic activity that was comparable (P > 0.05) to that of glibenclamide (1.0 μg/mL). Conclusions The results confirm pancreatic activity as a mechanism underlying the antidiabetic action of G. latifolium and justify its ethnomedical use.

Adebajo, AC, Odediran SA, Nneji CM, Iwalewa EO, Rukunga GM, Aladesanmi AJ, Gathirwa JW, Ademowo OG, Olugbade TA, Schmidt TJ, Verspohl EJ.  2013.  Evaluation of Ethnomedical Claims II: Antimalarial Activities of Gongronema latifolium Root and Stem. Journal of Herbs, Spices & Medicinal Plants. 19(2):97-118., Number 2: Taylor & Francis AbstractWebsite

Methanolic extract and chromatographic fractions of Gongronema latifolium were tested against clinical isolates of Plasmodium falciparum-, P. yoelii nigeriensis-infected mice, chloroquine-sensitive (D6) and chloroquine-resistant (W2) P. falciparum clones. The isolates, characterized as a 1:1 mixture of α-amyrin and β-amyrin cinnamates (1a/1b), lupenyl cinnamate (2) and lupenyl acetate (3), were assayed using the clones. Extract, most active vacuum liquid and column chromatographic fractions had respective ED50 values of 120.85, 32.03, 25.62 mg.kg-1 and IC50 of 36.27, 9.45, 7.05 μg.mL-1, against W2 clones. Lupenyl acetate had 18.96 μg.mL-1, indicating synergistic action of the constituents. Results justified its ethnomedical use for treating malaria.

2012
Adebajo, AC, Ayoola MD, Odediran SA, Aladesanmi AJ, Schmidt TJ, Verspohl EJ.  2012.  P 29: Insulinotropic constituents and evaluation of ethnomedical claim of Gongronema latifolium root and stem, 15-17th November. 5th Annual Meeting of the Diabetes and Cardio-vascular Disease EASD Study Group, Diabetes and Metabolism; 38(Suppl. 5), S115. Poster 29 . 38:S115., Paris, France: Elsevier {BV} Abstract

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Adebajo, AC.  2012.  P28 Some Contributions to the Evaluation of Ethnomedical Antidiabetic Claims of African Medicinal Plants, 15-17th November. 5th Annual Meeting of the Diabetes and Cardio-vascular Disease EASD Study Group, Diabetes and Metabolism; 38(Suppl. 5), S114-115. Poster 28. , Paris, France